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Nitrefazole

Product Name
Nitrefazole
CAS No.
21721-92-6
Chemical Name
Nitrefazole
Synonyms
bt-985;ALTIMOL;EMD 15700;NITREFAZOLE;1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE;2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol;2-methyl-4-nitro-1-(4-nitrophenyl)imidazole;2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol;2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole;1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)-
CBNumber
CB3356045
Molecular Formula
C10H8N4O4
Formula Weight
248.19
MOL File
21721-92-6.mol
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Nitrefazole Property

Melting point:
185-187°
storage temp. 
Refrigerator
solubility 
Chloroform (Slightly, Heated), DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
color 
Light Yellow to Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
N490125
Product name
Nitrefazole
Packaging
2.5g
Price
$1060
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
60642
Product name
Nitrefazole
Packaging
1g
Price
$640
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001431
Product name
ALTIMOL
Purity
95.00%
Packaging
10MG
Price
$641.55
Updated
2021/12/16
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Nitrefazole Chemical Properties,Usage,Production

Description

Nitrefazole is an inhibitor of aldehyde dehydrogenase useful in the management of alcoholism. Cited advantages over disulfiram include longer duration of action, higher specificity (no inhibition of dopamine β-hydroxylase) and fewer side effects. It is generally recognized that the efficacy of such agents with respect to permanent abstinence is low. However, temporary abstinence and/or controlled drinking may facilitate supportive psychotherapy and/or delay the onset of severe alcoholic diseases.

Originator

E. Merck (W. Germany)

Uses

Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase, and enzyme crucial to the metabolism of alcohol. This compound is suitable for aldehyde dehydrogenase (ALDH) related research.

Definition

ChEBI: Nitrefazole is a member of imidazoles.

brand name

ALTIMOL

World Health Organization (WHO)

Nitrefazole, which is used in the treatment of alcoholism, was introduced in the early 1980s. By 1984 its use had been associated with hepatotoxic reactions, some of which were fatal. This led to its withdrawal in at least two countries. WHO has no information to suggest that preparations containing nitrefazole remain commercially available.

Nitrefazole Preparation Products And Raw materials

Raw materials

Preparation Products

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Nitrefazole Suppliers

ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
6270
Advantage
58
Hefei Hirisun Pharmatech Co., Ltd
Tel
+8615056975894
Fax
86-0551-62678551
Email
shawn@hirisunpharm.com
Country
CHINA
ProdList
9911
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44806
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Dongyang Qiusuo Medical Technology Co., LTD
Tel
17502510579
Email
2785299132@qq.com
Country
China
ProdList
1558
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19885
Advantage
58

21721-92-6, NitrefazoleRelated Search:


  • ALTIMOL
  • 1-(4-NITROPHENYL)-2-METHYL-4-NITROIMIDAZOLE
  • EMD 15700
  • 2-methyl-4-nitro-1-(4-nitrophenyl)-1h-imidazol
  • 2-methyl-4-nitro-1-(4-nitrophenyl)imidazole
  • 2-methyl-4-nitro-1-(p-nitrophenyl)-imidazol
  • bt-985
  • NITREFAZOLE
  • 2-Methyl-4-nitro-1-(4-nitrophenyl)-1H-imidazole
  • 1H-Imidazole,2-methyl-4-nitro-1-(4-nitrophenyl)-
  • 21721-92-6
  • C10H8N4O4