ChemicalBook > CAS DataBase List > 1-BOC-2-METHYL-PIPERIDIN-4-ONE

1-BOC-2-METHYL-PIPERIDIN-4-ONE

Product Name
1-BOC-2-METHYL-PIPERIDIN-4-ONE
CAS No.
190906-92-4
Chemical Name
1-BOC-2-METHYL-PIPERIDIN-4-ONE
Synonyms
TERT-BUTYL 2-METHYL-4-OXOPIPERIDINE-1-CARBOXYLATE;N-Boc-2-methyl-piperidone;1-Boc-2-Methyl-Piperidinone;1-Boc-2-methyl-4-piperidi...;1-Boc-2-methyl-4-piperidinone;1-BOC-2-METHYL-PIPERIDIN-4-ONE;2-Methyl-4-oxo-piperidine-1-Boc;1-N-BOC-2-METHYL-PIPERIDIN-4-ONE;N-Boc-(+/-)-2-methyl-4-piperidone;2-Methyl-4-oxo-piperidine-1-Boc 97%
CBNumber
CB3358791
Molecular Formula
C11H19NO3
Formula Weight
213.27
MOL File
190906-92-4.mol
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1-BOC-2-METHYL-PIPERIDIN-4-ONE Property

Boiling point:
298.8±33.0 °C(Predicted)
Density 
1.060±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-1.52±0.40(Predicted)
form 
solid
color 
White to light yellow
InChI
InChI=1S/C11H19NO3/c1-8-7-9(13)5-6-12(8)10(14)15-11(2,3)4/h8H,5-7H2,1-4H3
InChIKey
HQMYWQCBINPHBB-UHFFFAOYSA-N
SMILES
N1(C(OC(C)(C)C)=O)CCC(=O)CC1C
CAS DataBase Reference
190906-92-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
Hazard Note 
Irritant
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H310Fatal in contact with skin

H341Suspected of causing genetic defects

H351Suspected of causing cancer

H360May damage fertility or the unborn child

H362May cause harm to breast-fed children

H370Causes damage to organs

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B423308
Product name
tert-Butyl2-Methyl-4-oxopiperidine-1-carboxylate
Packaging
50mg
Price
$45
Updated
2021/12/16
Apolloscientific
Product number
OR9058
Product name
2-Methylpiperidin-4-one,N-BOCprotected
Purity
97%
Packaging
1g
Price
$22
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-1-P7
Product name
2-Methylpiperidin-4-one, N-Boc protected
Packaging
1g
Price
$24
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140300
Product name
tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate
Packaging
250mg
Price
$50
Updated
2021/12/16
AK Scientific
Product number
S954
Product name
1-Boc-2-methyl-4-piperidinone
Packaging
250mg
Price
$78
Updated
2021/12/16
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1-BOC-2-METHYL-PIPERIDIN-4-ONE Chemical Properties,Usage,Production

Uses

1-Boc-2-methyl-piperidin-4-one s a crucial compound that could be used as a pharmaceutical intermediate in pharmaceutical synthesis and scientific research.

Synthesis

126503-08-0

190906-92-4

1-tert-butoxycarbonyl-2-methyl-4-piperidone vinyl acetal (6.00 g) was used as starting material and dissolved in acetone (150 mL). To this solution, p-toluenesulfonic acid monohydrate (4.40 g) was slowly added under ice bath cooling and stirring conditions. After addition, the reaction mixture was gradually warmed to room temperature with continuous stirring overnight. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate and the organic layer was subsequently washed with saturated sodium bicarbonate solution and saturated aqueous sodium chloride solution sequentially. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent to afford 1-tert-butoxycarbonyl-2-methyl-piperidone (2.40 g, 48% yield) as a yellow oil. Its 1H NMR (500 MHz, CDCl3) data were as follows: δ 1.18 (3H, d, J=7.0 Hz), 1.49 (9H, s), 2.20-2.30 (1H, m), 2.30-2.40 (1H, m), 2.45-2.55 (1H, m), 2.65-2.70 (1H, m), 3.25-3.35 ( 1H, m), 3.90-4.05 (1H, m), 4.20-4.30 (1H, m).

References

[1] Patent: EP1375482, 2004, A1. Location in patent: Page 153

1-BOC-2-METHYL-PIPERIDIN-4-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-2-METHYL-PIPERIDIN-4-ONE Suppliers

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View Lastest Price from 1-BOC-2-METHYL-PIPERIDIN-4-ONE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
1-BOC-2-METHYL-PIPERIDIN-4-ONE 190906-92-4
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27
Career Henan Chemical Co
Product
1-BOC-2-METHYL-PIPERIDIN-4-ONE 190906-92-4
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-08-05

190906-92-4, 1-BOC-2-METHYL-PIPERIDIN-4-ONERelated Search:

1-BOC-2-PHENYL-PIPERIDIN-4-ONE N-Boc-Nortropinone 1-BOC-2-BENZYL-PIPERIDIN-4-ONE 1-BOC-2-METHYL-PIPERIDIN-4-ONE 2-Methyl-4-piperidone 1-BOC-2-ETHYL-PIPERIDIN-4-ONE TERT-BUTYL 5-OXO-2-AZABICYCLO[2.2.1]HEPTANE-2-CARBOXYLATE 1-Piperidinecarboxylicacid,2-methyl-4-oxo-,1,1-dimethylethylester,(2R)-(9CI) 1-Piperidinecarboxylicacid,2-methyl-4-oxo-,1,1-dimethylethylester,(2S)-(9CI) TERT-BUTYL 4-OXO-1-AZASPIRO[5.5]UNDECANE-1-CARBOXYLATE 1-BOC-2-ISOPROPYL-PIPERIDIN-4-ONE TERT-BUTYL (2S)-2-BENZYL-4-OXOPIPERIDINE-1-CARBOXYLATE 1-BOC-2-TERT-BUTYL-PIPERIDIN-4-ONE tert-butyl 8-oxo-5-azaspiro[3.5]nonane-5-carboxylate TERT-BUTYL (2R)-2-BENZYL-4-OXOPIPERIDINE-1-CARBOXYLATE 1-BOC-2-PROPYL-PIPERIDIN-4-ONE 1-BOC-3-METHYL-PIPERIDIN-4-ONE (2S)-N-BOC-4-OXOPIPECOLIC ACID

  • 1-BOC-2-METHYL-PIPERIDIN-4-ONE
  • 2-METHYL-4-OXOPIPERIDINE, N-BOC PROTECTED
  • 1-N-BOC-2-METHYL-PIPERIDIN-4-ONE
  • 1-TERT-BUTOXYCARBONYL-2-METHYL-4-PIPERIDONE
  • TERT-BUTYL 2-METHYL-4-OXOPIPERIDINE-1-CARBOXYLATE
  • 1-Boc-2-methyl-4-piperidinone
  • 1-Boc-2-Methyl-Piperidinone
  • 2-Methyl-4-oxopiperidine, N-BOC protected 97%
  • N-Boc-2-methyl-piperidone
  • 1-(tert-Butoxycarbonyl)-2-methylpiperidin-4-one
  • 2-Methyl-4-oxo-piperidine-1-carboxylic acid tert-butyl ester
  • 1-Boc-2-methyl-4-piperidi...
  • 2-Methyl-4-oxo-piperidine-1-Boc
  • 2-Methyl-4-oxopiperidine, N-BOC protected, tert-Butyl 2-methyl-4-oxopiperidine-1-carboxylate, 1-(tert-Butoxycarbonyl)-2-methylpiperidin-4-one
  • 2-Methylpiperidin-4-one, N-BOC protected 97%
  • 1-Piperidinecarboxylicacid,2-Methyl-4-oxo-,1,1-diMethylethylester
  • tert-butyl 2-Methyl-3-oxopiperidine-1-carboxylate
  • 2-Methyl-4-oxo-piperidine-1-Boc 97%
  • utyl 2-Methyl-4-oxopiperidine-1-carboxylate
  • 1-Boc-2-Methyl-4-piperidinone/tert-butyl 2-Methyl-4-oxopiperidine-1-carboxylate
  • 2-Methylpiperidin-4-one, N-BOC protected
  • N-Boc-(+/-)-2-methyl-4-piperidone
  • 190906-92-4
  • Pyrans, Piperidines & Piperazines
  • pharmacetical
  • Pyrans, Piperidines &Piperazines
  • Piperidine
  • Piperidines