ChemicalBook > CAS DataBase List > 4-Bromophenylboronic acid

4-Bromophenylboronic acid

Product Name
4-Bromophenylboronic acid
CAS No.
5467-74-3
Chemical Name
4-Bromophenylboronic acid
Synonyms
4-bromophenylboric acid;4-BROMOBENZENEBORONIC ACID;p-BBBA;NSC 25407;AKOS BRN-0005;RARECHEM AH PB 0075;4-Bromophenylboronic;p-bromophenylboricacid;Flortaucipir Impurity 25;4-BROMOPHENYLBORONIC ACID
CBNumber
CB3361760
Molecular Formula
C6H6BBrO2
Formula Weight
200.83
MOL File
5467-74-3.mol
More
Less

4-Bromophenylboronic acid Property

Melting point:
284-288 °C (lit.)
Boiling point:
315.0±44.0 °C(Predicted)
Density 
1.67±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Crystalline Powder
pka
8.32±0.10(Predicted)
color 
Off-white to light beige
Water Solubility 
Soluble in methanol. Insoluble in water.
BRN 
2936347
InChI
InChI=1S/C6H6BBrO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4,9-10H
InChIKey
QBLFZIBJXUQVRF-UHFFFAOYSA-N
SMILES
B(C1=CC=C(Br)C=C1)(O)O
CAS DataBase Reference
5467-74-3(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-22
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
CY8650000
TSCA 
T
HazardClass 
IRRITANT
HS Code 
29319090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B75956
Product name
4-Bromophenylboronic acid
Purity
≥95.0%
Packaging
5g
Price
$88.2
Updated
2025/07/31
TCI Chemical
Product number
B1858
Product name
4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
1g
Price
$20
Updated
2025/07/31
TCI Chemical
Product number
B1858
Product name
4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
5g
Price
$51
Updated
2025/07/31
TCI Chemical
Product number
B1858
Product name
4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
25g
Price
$143
Updated
2025/07/31
TRC
Product number
B686545
Product name
4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
Packaging
100g
Price
$1075
Updated
2021/12/16
More
Less

4-Bromophenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

suzuki reaction

Uses

4-Bromobenzeneboronic acid is a reagent used for Palladium catalyzed Suzuki-Miyaura cross-couplings, Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence. It is also used in the preparation of Protein modulators and enzymatic and kinase inhibitors, Gallate-based obovatol analogs with potential anti-tumor activity. It is used as a reagent for Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, Pd-catalyzed arylative cyclization of alkyne-tethered enals or enones via carbopalladation of alkynes, Copper-catalyzed cross-couplings.

Uses

Labelled 4-Bromophenylboronic Acid (B686545). 4-Bromophenylboric acid is used in the preparation of arylboronates as inhibitors of fatty acid amide hydrolase.

Synthesis

106-40-1

5467-74-3

GENERAL METHOD: 4-Bromoaniline (0.5 mmol, 1.0 eq.) was dissolved in methanol (1.0 mL), hydrochloric acid (0.5 mL, 1.5 mmol, 3.0 eq.) and water (0.5 mL) were added. The reaction mixture was stirred for 2 min and then sodium nitrite solution (0.25 mL, prepared by dissolving 35 mg of sodium nitrite in 0.25 mL of water) was added. Stir at 0-5 °C for 30 min, followed by the addition of hydrochloric acid (135 mg, 1.5 mmol, 3.0 equiv) in methanol (1.0 mL). Stirring was continued for 60 min. After completion of the reaction, it was diluted with water (10 mL) and extracted with dichloromethane (50 mL, 3 times). The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 4-bromophenylboronic acid.

References

[1] Synlett, 2014, vol. 25, # 11, p. 1577 - 1584
[2] Chemistry - A European Journal, 2014, vol. 20, # 22, p. 6608 - 6612

4-Bromophenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-Bromophenylboronic acid Suppliers

Americas 1 Belgium 5 China 394 Europe 4 France 4 Germany 20 India 36 Japan 5 Jordan 1 Russia 1 Slovakia 1 South Korea 1 Switzerland 2 Ukraine 1 United Kingdom 24 United States 71 Global 571
Beijing Green Guardee Technology CO,.LTD
Tel
010-69706062-8011 15045616674
Fax
+86-10-69706062
Email
zhangr@greenguardee.com
Country
China
ProdList
291
Advantage
56
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2805
Advantage
65
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Puyang Huicheng Electronic Material Co. Ltd.
Tel
0393-0393-0393-8910800 15039333257
Fax
0393-8912775
Email
info@huichengchem.com
Country
China
ProdList
569
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16075
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527621225
Email
1791901229@qq.com
Country
China
ProdList
6945
Advantage
52
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Xi’an chemsoar Medical Technology Co., ltd
Tel
029-86538357
Fax
029-87871708
Country
China
ProdList
234
Advantage
57
shanghai Rainbow MediTech.Co.Ltd.
Tel
021-64968085,64968086-5815,5812; 13472757003
Fax
+86 21 64968087
Email
xiaoxia.zeng@rainbowpharma.cn
Country
China
ProdList
961
Advantage
65
HANSHANG CHEMICAL SCIENTIFIC LIMITED
Tel
021-50521775 15800962688
Fax
86-21-58306291
Email
sales@hanshangchem.com
Country
China
ProdList
471
Advantage
57
DKD Shijiazhuang Chemical Co., Ltd.
Tel
0311-0311-67790228 15531158659
Fax
66571013
Email
1257738041@qq.com
Country
China
ProdList
297
Advantage
62
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Xuchang Haofeng Chemical Co., Ltd.
Tel
0374-5695198
Fax
0374-5695198
Email
haofengchemical@163.com
Country
China
ProdList
50
Advantage
62
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Wuhan Kemi-Works Chemical Co., Ltd
Tel
027-85736489
Fax
86-27-85736485
Email
info@kemiworks.net
Country
China
ProdList
540
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
7247
Advantage
62
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4378
Advantage
65
Springchem New Material Technology Co.,Limited
Tel
+86-021-62885108 +8613917661608
Email
info@spring-chem.com
Country
China
ProdList
2068
Advantage
57
Explovisual Technology Incorporation
Tel
+86 (519) 8829-2061
Fax
+86 (519) 8829-2061
Email
explovisual@hotmail.com
Country
China
ProdList
296
Advantage
60
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 17550508557
Fax
QQ：3470079902
Email
675141927@qq.com
Country
China
ProdList
3199
Advantage
55
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4000
Advantage
55
Wuhan Fortuna Chemical Co., Ltd
Tel
027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2744
Advantage
58
Wuhan Haizheng Industry & Trade Development Co. Ltd
Tel
027-8866 0053/88660577/88660578
Fax
027-8899 1911
Country
China
ProdList
1073
Advantage
55
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
Yurui (Shanghai) Chemical Co., Ltd.
Tel
+86-02150456736 +86-18602143071
Fax
021-50761379
Email
xin@riyngroup.com
Country
China
ProdList
500
Advantage
30
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq：2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
Candia Thamtech Company Limited
Tel
0371-86615086 18203638366 0371-86159066 13526786601
Fax
0371-86159066
Country
China
ProdList
2015
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
More
Less

View Lastest Price from 4-Bromophenylboronic acid manufacturers

Shaanxi Didu New Materials Co. Ltd
Product
4-Bromophenylboronic acid 5467-74-3
Price
US $1.50/g
Min. Order
1g
Purity
99.0% Min
Supply Ability
10 Tons
Release date
2025-06-24
Hebei Zhuanglai Chemical Trading Co Ltd
Product
4-Bromophenylboronic acid 5467-74-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-25
Hebei Chuanghai Biotechnology Co,.LTD
Product
4-Bromophenylboronic acid 5467-74-3
Price
US $9.00/KG
Min. Order
1KG
Purity
99.9
Supply Ability
1 ton
Release date
2024-08-21

5467-74-3, 4-Bromophenylboronic acidRelated Search:

2-Bromobenzonitrile 4-Bromobenzaldehyde Bromoxynil octanoate Phenylboronic acid 3-Bromoanisole Zinc borate Fluoroboric acid 4'-Bromopropiophenone Triphenylphosphine 2-Phenylphenol 2-Bromofluorobenzene 4-BROMO-2 6-DIFLUOROPHENYLBORONIC ACID 4-BROMO-2-FLUOROBENZENEBORONIC ACID 4-BROMO-3-FLUOROBENZENEBORONIC ACID 4-Bromo-2,5-dimethylphenylboronic acid 4-BROMOPHENYLBORONIC ACID N-METHYL DIETHANOLAMI,4-BROMOPHENYLBORONIC ACID N-METHYL DIETHANOLAMINE CYCLIC ESTER 4-BROMOPHENYLBORONIC ACID NEOPENTYL GLYCOL CYCLIC ESTER Phenylacetone

  • AKOS BRN-0005
  • 4-BROMOPHENYLBORIC ACID ANHYDRIDE
  • 4-BROMOPHENYLBORONIC ACID
  • 4-BROMOBENZENEBORONIC ACID
  • 4-BROMOBENZENEBORONIC ACID/ANHYDRIDE
  • RARECHEM AH PB 0075
  • P-BROMO BENZENE BORONIC ACID
  • P-BROMOPHENYLBORONIC ACID
  • (4-bromophenyl)-boronicaci
  • p-bromo-benzeneboronicaci
  • p-bromophenylboricacid
  • p-BBBA
  • NSC 25407
  • 4-Bromophenylboronic acid >=95.0%
  • Boronic acid,B-(4-bromophenyl)-
  • 4-Bromobenzeneboronic acid4-Bromobenzene
  • dihydroxy-4-bromophenylborane
  • 4-Bromobenzeneboronicacid,97+%
  • 4-Bromophenylboronic
  • Boronic acid, (4-bromophenyl)-
  • 4-bromophenylboric acid
  • 4-Bromobenzeneboronic acid4-Bromobenzeneboronic acid
  • (4-Bromophenyl)boranediol
  • (4-Bromophenyl)boranic acid
  • 4-Bromophenylboranic acid
  • 4-Bromophenylboron dihydoxide
  • 4-Bromophenylboronic acid,98%
  • 4-Bromophenylboronic Acid (contains varying amounts of Anhydride)
  • 4-Bromophenylboronic acid , May contain varying amounts of anhydride, 97%
  • Boronic acid, B-(4-bromopheny)-
  • 4-Bromophenylboronic Acid-d4 (contains varying amounts of Anhydride)
  • 5467-74-3 4-Bromophenylboronic acid
  • 4-Bromophenylboronic acid extrapure, 97%
  • Flortaucipir Impurity 25
  • 4-Bromophenylboronic acid, 97%
  • 4-Bromophenylboronic acid - [B1940]
  • (4-Bromopheny|)boronic acid
  • 5467-74-3
  • 5467-74-6
  • 5467-73-3
  • 5467-76-3
  • 5464-74-3
  • BrC6H4BOH2
  • BORONIC ACID
  • Boronic Acids
  • Aryl
  • Boronic Acids and Derivatives
  • B (Classes of Boron Compounds)
  • Organometallic Reagents
  • Boronate Ester
  • Potassium Trifluoroborate
  • OLED materials,pharm chemical,electronic
  • B (Classes of Boron Compounds)
  • Boronic acids
  • Boronic Acid
  • Aryl
  • Halogenated
  • Organoborons