4-Chloroindoline
- Product Name
- 4-Chloroindoline
- CAS No.
- 41910-64-9
- Chemical Name
- 4-Chloroindoline
- Synonyms
- 4-CHLOROINDOLINE;BUTTPARK 120\07-96;4-Chloroindoline 97%;4-CHLOROINDOLINE ,99%;D-3-Chlorophenylglycine;4-CHLORO-2,3-DIHYDRO-1H-INDOLE;1H-Indole, 4-chloro-2,3-dihydro-;4-CHLORO-2,3-DIHYDRO-1H-INDOLE HYDROCHLORIDE;4-Chloroindoline 4-Chloro-2,3-dihydro-1H-indole in stock Factory
- CBNumber
- CB3366093
- Molecular Formula
- C8H8ClN
- Formula Weight
- 153.61
- MOL File
- 41910-64-9.mol
4-Chloroindoline Property
- Boiling point:
- 135 °C(Press: 10 Torr)
- Density
- 1.214±0.06 g/cm3(Predicted)
- refractive index
- 1.603
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 4.26±0.20(Predicted)
- CAS DataBase Reference
- 41910-64-9(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C349505
- Product name
- 4-Chloroindoline
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- C349505
- Product name
- 4-Chloroindoline
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FC51061
- Product name
- 4-Chloroindoline
- Packaging
- 2g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 38144
- Product name
- 4-Chloroindoline
- Purity
- 95+%
- Packaging
- 1g
- Price
- $331
- Updated
- 2021/12/16
- Product number
- 38144
- Product name
- 4-Chloroindoline
- Purity
- 95+%
- Packaging
- 5G
- Price
- $404
- Updated
- 2021/12/16
4-Chloroindoline Chemical Properties,Usage,Production
Synthesis
25235-85-2
41910-64-9
GENERAL STEPS: The synthesis of 4-chloroindoline from 4-chloroindole was carried out as follows: 4-chloroindole (20.0 g, 148 mmol) was dissolved in acetic acid (60 mL), followed by the addition of sodium cyanoborohydride (18.7 g, 296 mmol) in batches. The reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the mixture was slowly poured into 1500 mL of a 2 M NaOH aqueous solution. The aqueous phase was extracted with dichloromethane (CH2Cl2) and the organic layers were combined. The organic layer was washed with saturated brine, dried over anhydrous magnesium sulfate (MgSO4) and concentrated under reduced pressure to give 4-chloroindoline (20.0 g, 98% yield). The product was confirmed by 1H NMR (400MHz, CDCl3): δ3.08 (2H, triple peak, J=8.4Hz), 3.62 (2H, triple peak, J=8.4Hz), 6.62-6.66 (1H, multiple peaks), 6.78-6.83 (1H, multiple peaks), 6.90 (1H, double double peaks, J=7.6,0.4Hz).
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 5, p. 1649 - 1666
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 166 - 178
[3] Journal of Medicinal Chemistry, 1998, vol. 41, # 10, p. 1598 - 1612
[4] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 21, p. 3105 - 3109
[5] Patent: US2008/27014, 2008, A1. Location in patent: Page/Page column 39
4-Chloroindoline Preparation Products And Raw materials
Raw materials
Preparation Products
4-Chloroindoline Suppliers
- Tel
- 0535-6385396
- Fax
- +86 (535) 638-9971
- info@carbottpharm.com
- Country
- China
- ProdList
- 957
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- Fax
- E-Mail Inquiry
- info@syntechem.com
- Country
- China
- ProdList
- 12984
- Advantage
- 57
- Tel
- 18270980682
- Fax
- 021 51613951
- mlcheng@sunwaypharm.cn
- Country
- China
- ProdList
- 8669
- Advantage
- 57
- Tel
- Please Send Email 18652950785
- Fax
- 025-87193546
- chemweiao@163.com
- Country
- China
- ProdList
- 4378
- Advantage
- 65
- Tel
- 027-8866 0053/88660577/88660578
- Fax
- 027-8899 1911
- Country
- China
- ProdList
- 1073
- Advantage
- 55
- Tel
- 028-85114309 18982182443
- yangli@happysyn.com
- Country
- China
- ProdList
- 2150
- Advantage
- 55
- Tel
- +91-11-26135922 or +91-11-46160359
- Fax
- +91-11-26124735
- labex@labex.net
- Country
- India
- ProdList
- 391
- Advantage
- 55
View Lastest Price from 4-Chloroindoline manufacturers
- Product
- 4-Chloroindoline 4-Chloro-2,3-dihydro-1H-indole in stock Factory 41910-64-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- TOP 3 Factory in China
- Supply Ability
- Top 3 production capacity Factory
- Release date
- 2019-04-03
- Product
- 4-Chloroindoline 41910-64-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kgs
- Release date
- 2020-01-09