Dimethylaminopropionitrile Property

Melting point:

−43 °C(lit.)

Boiling point:

171 °C750 mm Hg(lit.)

Density 

0.87 g/mL at 25 °C(lit.)

refractive index 

n20/D 1.426(lit.)

Flash point:

145 °F

storage temp. 

2-8°C

form 

Liquid

pka

8.17±0.28(Predicted)

color 

Clear colorless to yellow

PH

10.8 (100g/l, H2O, 20℃)

explosive limit

1.6-11.4%(V)

Water Solubility 

0.5 g/L (20 ºC)

BRN 

773779

CAS DataBase Reference

1738-25-6(CAS DataBase Reference)

NIST Chemistry Reference

Propanenitrile, 3-(dimethylamino)-(1738-25-6)

EPA Substance Registry System

Dimethylaminopropionitrile (1738-25-6)

Safety

Hazard Codes 

Xn

Risk Statements 

22-36-36/38-21

Safety Statements 

26-36/37-24/25

RIDADR 

2927

WGK Germany 

1

RTECS 

UG1575000

F 

8

TSCA 

Yes

HazardClass 

6.1(a)

PackingGroup 

II

HS Code 

29269095

Hazardous Substances Data

1738-25-6(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H303May be harmfulif swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

Dimethylaminopropionitrile Chemical Properties,Usage,Production

Chemical Properties

clear colorless liquid

Uses

3-(Dimethylamino)propionitrile has been used:

• to initiate the organic polymerization during the synthesis of class I hybrid poly(N-isopropylacrylamide)/silica hydrogels
• in preparation of cysteine modifying agents based on the solvatochromic fluorophore 4-N,N-dimethylamino-1,8-naphthalimide (4-DMN)

Uses

3- Dimethylaminopropionitrile is used as a solvent, dielectric fluid, and an intermediate.

Production Methods

3-Dimethylaminopropionitrile is derived from heating barium ethyl sulfate and KCN with subsequent distillation.

General Description

Colorless liquid. Mp: -44.3°C; bp: 171-172°C. Density 0.87 g cm-3 at 20°C). Water-soluble. Used in the manufacture of polyurethane foam. Excessive exposure leads to urologic and neurologic disorders.

Reactivity Profile

Dimethylaminopropionitrile is combustible but non-flammable (flash point > 140°F), reacts with oxidizing agents (Hazardous Chemicals Desk Reference, p. 426 (1987)). Reacts violently with LIAlH4, a strong reducing agent. Emits toxic oxides of nitrogen and cyanide fumes when heated to decomposition.

Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and skin contact. A skin and eye irritant. Flammable liquid when exposed to heat, flame, or oxidizers; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of NOx and CN-. See also NITRILES.