2-Methoxypyridine

Product Name: 2-Methoxypyridine
CAS No.: 1628-89-3
Chemical Name: 2-Methoxypyridine
Synonyms: 2-METHOXYPYRIDINE;2-Methoxyl pyridine;2-Methoxypyridine>2-Methoxypyridine98%;2-Methoxypyridine 99%;2-Pyridol methyl ether;METHYL 2-PYRIDYL ETHER;Methyl pyridin-2-yl ether;2-METHOXY PYRIDINE FEMA NO.--------;2-Methoxypyridine ISO 9001：2015 REACH
CBNumber: CB3396719
Molecular Formula: C6H7NO
Formula Weight: 109.13
MOL File: 1628-89-3.mol

More

Less

2-Methoxypyridine Property

Boiling point:: 142 °C (lit.)
Density: 1.038 g/mL at 25 °C (lit.)
refractive index: n20/D 1.503(lit.)
FEMA: 4639 | 2-METHOXYPYRIDINE
Flash point:: 90 °F
storage temp.: Inert atmosphere,Room Temperature
form: Liquid
pka: 3.28(at 20℃)
color: Clear colorless to slightly yellow
Odor: at 0.10?%?in?propylene glycol. green fermented tea
Appearance: Colorless to Light yellow clear liquid
Water Solubility: INSOLUBLE
JECFA Number: 2156
BRN: 108189
InChIKey: IWTFOFMTUOBLHG-UHFFFAOYSA-N
LogP: 1.32
CAS DataBase Reference: 1628-89-3(CAS DataBase Reference)
NIST Chemistry Reference: Pyridine, 2-methoxy-(1628-89-3)

More

Less

Safety

Hazard Codes: Xi,F
Risk Statements: 10-36/37/38
Safety Statements: 26-36-16
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
HazardClass: 3
PackingGroup: III
HS Code: 29339900

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W463901
Product name: 2-Methoxypyridine
Purity: ≥98%
Packaging: 100G
Price: $109
Updated: 2025/07/31

Sigma-Aldrich

Product number: W463901
Product name: 2-Methoxypyridine
Purity: ≥98%
Packaging: 1 unit
Price: $174
Updated: 2025/07/31

Sigma-Aldrich

Product number: W463901
Product name: 2-Methoxypyridine
Purity: ≥98%
Packaging: 1 unit
Price: $174
Updated: 2025/07/31

Sigma-Aldrich

Product number: W463901
Product name: 2-Methoxypyridine
Purity: ≥98%
Packaging: 1KG
Price: $428
Updated: 2025/07/31

Sigma-Aldrich

Product number: M25406
Product name: 2-Methoxypyridine
Purity: 98%
Packaging: 25g
Price: $41.9
Updated: 2025/07/31

More

Less

2-Methoxypyridine Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to slightly yellow liquid

Uses

2-Methoxypyridine can be used as an intermediate to synthesize 2-methoxy-3-pyridinesulfonyl chloride which is patented as a reactant used to prepare erythromycin macrolide antibiotics as antibacterial and antiprotozoal agents. It can also be used to prepare bicyclic iminopyrimidinones as Beta Amyloid Cleaving Enzyme-1 (BACE1) inhibitors.

Synthesis

CsSO4F may be used to fluorinate pyridine directly, but the reaction is very sensitive to the solvents employed. When solvents such as pentane and diethyl ether were used, 2-fluoropyridine was the major product, but use of nucleophilic solvents, such as methanol gave 2-methoxypyridine.

References

[1] DAI W, LIU S, ZHANG Z, et al. Conformational preferences and isomerization upon excitation/ionization of 2-methoxypyridine and 2-N-methylaminopyridine†[J]. Physical Chemistry Chemical Physics, 2018, 9: 6211-6226. DOI:10.1039/C7CP07854D.
[2] Singh, Avtar, et al. "Synthesis of C-6 and C-3 substituted chalcogen derivatives of 2-methoxypyridine through lithiation of 2-methoxypyridine: An experimental and quantum chemical study." Inorganica Chimica Acta 432 (2015): 109-114.
[3] Trécourt, F., et al. "Catalyzed metalation applied to 2-methoxypyridine." The Journal of Organic Chemistry 53.7 (1988): 1367-1371.
[4] Ahipa, T. N., and Airody Vasudeva Adhikari. "2-Methoxypyridine derivatives: synthesis, liquid crystalline and photo-physical properties." New Journal of Chemistry 38.10 (2014): 5018-5029.
[5] WANYING CHENG . Conformation and bonding of 2-methoxypyridine and its monohydrate from rotational spectra[J]. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2020, 239: Article 118434. DOI:10.1016/j.saa.2020.118434.

2-Methoxypyridine Preparation Products And Raw materials

Raw materials

Preparation Products

2-Pyridinol-1-oxide 6-Methoxynicotinaldehyde 7-CHLORO-10-(4-HYDROXYANILINO)-2-METHOXY BENZO(B)-1,5-NAPHTHY RIDINE 2-Methoxypyridine-3-boronic acid 2-METHOXY-3-PYRIDINECARBOXALDEHYDE 4-Amino-2-methoxypyridine

More

Less

2-Methoxypyridine Suppliers

Americas 2 Belgium 3 China 270 Europe 4 France 1 Germany 9 India 47 Ireland 1 Japan 3 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 17 United States 49 USA 1 Global 411

Weifang Siyuan Chemical Co., Ltd.

Tel: 0536-8888106 17663601818
Fax: 0536-8888106
Email: 2354379876@qq.com
Country: China
ProdList: 245
Advantage: 58

Wuhan EnTai Technology Development Co,.Ltd

Tel: 86-27-82330560
Fax: 86-27-82330547
Email: 2536851935@qq.com
Country: China
ProdList: 347
Advantage: 69

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

More

Less

View Lastest Price from 2-Methoxypyridine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 2-Methoxypyridine 1628-89-3
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 1000kg
Release date: 2025-09-09

Shanghai Yongzeng Technology Co.,Ltd

Product: 2-methoxypyridine 1628-89-3
Price: US $0.00/gm
Min. Order: 100gm
Purity: 99%min
Supply Ability: 100kgs
Release date: 2024-09-04

JINING XINHE CHEMICAL CO., LTD

Product: 2-Methoxypyridine 1628-89-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10ton
Release date: 2024-07-17

1628-89-3, 2-MethoxypyridineRelated Search:

2,6-Dimethoxypyridine 2-Methoxy-3-nitropyridine 6-Chloro-2-methoxypyridine 2-PHENOXYNICOTINONITRILE 3-AMINO-2,6-DIMETHOXYPYRIDINE MONOHYDROCHLORIDE 2-Methoxypyridine 2-PHENOXYNICOTINIC ACID 2-ALLYLOXYPYRIDINE 2-N-BUTOXYPYRIDINE 2-CHLORO-6-ETHOXYPYRIDINE 2-Ethoxypyridine 2-Methoxy-5-nitropyridine Pyridine,3,4-dimethoxy-(9CI) 5-FLUORO-2-METHOXYPYRIDINE 6-METHOXYPYRIDINE-2-CARBOXYLIC ACID 2-(2-FORMYL-1H-PYRROL-1-YL)-4-METHOXYNICOTINONITRILE 5-FLUORO-4-FORMYL-2-METHOXYPYRIDINE 6-methoxypyridine-2,3-diamine dihydrochloride

METHYL 2-PYRIDYL ETHER

2-METHOXYPYRIDINE

2-Methoxypyridine98%

2-Methoxypyridine 99%

Methyl pyridin-2-yl ether

2-Methoxyl pyridine

2-Pyridol methyl ether

2-METHOXY PYRIDINE FEMA NO.--------

2-Methoxypyridine&gt

2-Methoxypyridine ISO 9001：2015 REACH

1628-89-3

Building Blocks

Heterocyclic Building Blocks

Pyridines

C6

Pyridines, Pyrimidines, Purines and Pteredines

Pyridines derivates

Pyridines

Anisoles, Alkyloxy Compounds & Phenylacetates

Miscellaneous Compounds

Heterocyclic Building Blocks

Pyridine

bc0001

C6