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METHYL 1-METHYLPYRROLE-2-CARBOXYLATE

Product Name
METHYL 1-METHYLPYRROLE-2-CARBOXYLATE
CAS No.
37619-24-2
Chemical Name
METHYL 1-METHYLPYRROLE-2-CARBOXYLATE
Synonyms
RARECHEM AL BF 0084;2-Methoxycarbonyl-1-methylpyrrole;Methyl 1-Methyl-2-pyrrolecarboxylate;methyl N-methylpyrrole-2-carboxylate;Methyl-4-methylpyrrole-2-carboxylate;METHYL 1-METHYLPYRROLE-2-CARBOXYLATE;Methyl1-methylpyrrole-2-carboxylate,98%;METHYL 1-METHYL-1H-PYRROLE-2-CARBOXYLATE;1-METHYLPYRROLE-2-CARBOXYLIC ACID METHYL ESTER;1-Methyl-1H-pyrrole-2-carboxylic acid methyl ester
CBNumber
CB3407697
Molecular Formula
C7H9NO2
Formula Weight
139.15
MOL File
37619-24-2.mol
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METHYL 1-METHYLPYRROLE-2-CARBOXYLATE Property

Melting point:
80 °C (sublm)(Press: 0.2 Torr)
Boiling point:
96-98°C 15mm
Density 
1.07±0.1 g/cm3(Predicted)
refractive index 
1.5220
Flash point:
96-98°C/15mm
storage temp. 
Sealed in dry,Room Temperature
pka
-7.04±0.70(Predicted)
Appearance
Light yellow to brown Liquid
Water Solubility 
Slightly soluble in water.
BRN 
116477
CAS DataBase Reference
37619-24-2(CAS DataBase Reference)
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Safety

HazardClass 
IRRITANT
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B451520
Product name
Methyl1-Methylpyrrole-2-carboxylate
Packaging
100mg
Price
$75
Updated
2021/12/16
Matrix Scientific
Product number
045456
Product name
Methyl 1-methyl-1H-pyrrole-2-carboxylate
Purity
>95%
Packaging
5g
Price
$59
Updated
2021/12/16
SynQuest Laboratories
Product number
4H23-1-4S
Product name
Methyl 1-methyl-1H-pyrrole-2-carboxylate
Packaging
1g
Price
$96
Updated
2021/12/16
Matrix Scientific
Product number
045456
Product name
Methyl 1-methyl-1H-pyrrole-2-carboxylate
Purity
>95%
Packaging
500mg
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
045456
Product name
Methyl 1-methyl-1H-pyrrole-2-carboxylate
Purity
>95%
Packaging
1g
Price
$14
Updated
2021/12/16
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METHYL 1-METHYLPYRROLE-2-CARBOXYLATE Chemical Properties,Usage,Production

Uses

Methyl 1-methylpyrrole-2-carboxylate is used as chemical and organic Intermediates.

Synthesis

1193-62-0

74-88-4

37619-24-2

Methyl-1H-pyrrole-2-carboxylate (10 g, 79.9 mmol) was dissolved in anhydrous THF (200 mL) at 0 °C and NaH (3.52 g, 60% w/w, 87.9 mmol) was slowly added. The reaction mixture was stirred at 20 °C for 30 min before CH3I (13.62 g, 95.9 mmol) was added dropwise. The reaction was continued to be stirred at 20 °C for 17 hours. After completion of the reaction, the reaction was quenched by slowly pouring the mixture into aqueous NH4Cl (200 mL). The aqueous phase was extracted with EtOAc (200 mL x 2), the organic layers were combined and washed with brine (150 mL), dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: EtOAc/petroleum ether=1/20) to afford methyl 1-methyl-1H-pyrrole-2-carboxylate (9.88 g, 71 mmol, 89% yield) as a yellow oil. Mass spectrum (EI+, m/z): 140.1 [M+H]+.

References

[1] Organic Letters, 2015, vol. 17, # 11, p. 2652 - 2655
[2] Patent: WO2018/89493, 2018, A1. Location in patent: Paragraph 00214
[3] Bioorganic and Medicinal Chemistry Letters, 2008, vol. 18, # 11, p. 3219 - 3223

METHYL 1-METHYLPYRROLE-2-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHYL 1-METHYLPYRROLE-2-CARBOXYLATE Suppliers

China 97 Germany 3 India 3 United Kingdom 7 United States 11 Global 121
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
Rare Chemicals GmbH
Tel
--
Fax
--
Email
sales@rarechem.de
Country
Germany
ProdList
6297
Advantage
38
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View Lastest Price from METHYL 1-METHYLPYRROLE-2-CARBOXYLATE manufacturers

Career Henan Chemical Co
Product
METHYL 1-METHYLPYRROLE-2-CARBOXYLATE 37619-24-2
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2019-12-25

37619-24-2, METHYL 1-METHYLPYRROLE-2-CARBOXYLATERelated Search:

TERT-BUTYL 1-METHYL-4-NITRO-1H-PYRROLE-2-CARBOXYLATE METHYL 1-METHYLPYRROLE-2-CARBOXYLATE methyl 1-methyl-1H-indole-2-carboxylate METHYL 2,5-DIMETHYLPYRROLE-3-CARBOXYLATE Methyl 2-pyrrolecarboxylate ETHYL 1-(4-CHLOROBENZYL)-3-(1H-PYRROL-1-YL)-1H-INDOLE-2-CARBOXYLATE ETHYL 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRROLE-2-CARBOXYLATE ETHYL 4-CHLORO-5-METHYL-7-PHENYL-7H-PYRROLO[2,3-D]PYRIMIDINE-6-CARBOXYLATE METHYL 4-(2,4-DICHLOROBENZOYL)-1-METHYL-1H-PYRROLE-2-CARBOXYLATE METHYL 4-ACETYL-1-METHYL-1H-PYRROLE-2-CARBOXYLATE ETHYL 1-(4-METHYLBENZYL)-3-(1H-PYRROL-1-YL)-1H-INDOLE-2-CARBOXYLATE METHYL 4-(2,3-DICHLOROBENZOYL)-1-METHYL-1H-PYRROLE-2-CARBOXYLATE ETHYL 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3-(1H-PYRROL-1-YL)-1H-INDOLE-2-CARBOXYLATE 3-OXO-1-CYCLOHEXENYL 1-[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-1H-PYRROLE-2-CARBOXYLATE ETHYL 1-(2-CHLOROBENZYL)-3-(1H-PYRROL-1-YL)-1H-INDOLE-2-CARBOXYLATE 4H,6H-BENZO[E]PYRROLO[2,1-C][1,4]OXAZEPINE-4,6-DIONE METHYL 5-[2-(4-CHLOROPHENYL)-1-CYANOVINYL]-1-METHYL-1H-PYRROLE-2-CARBOXYLATE ETHYL 1-BENZYL-3-(1H-PYRROL-1-YL)-1H-INDOLE-2-CARBOXYLATE

  • RARECHEM AL BF 0084
  • 1-METHYLPYRROLE-2-CARBOXYLIC ACID METHYL ESTER
  • METHYL 1-METHYL-1H-PYRROLE-2-CARBOXYLATE
  • METHYL 1-METHYLPYRROLE-2-CARBOXYLATE
  • Methyl-4-methylpyrrole-2-carboxylate
  • 1-Methyl-1H-pyrrole-2-carboxylic acid methyl ester
  • methyl N-methylpyrrole-2-carboxylate
  • 1H-Pyrrole-2-carboxylicacid, 1-methyl-, methyl ester
  • Methyl 1-Methyl-2-pyrrolecarboxylate
  • Methyl1-methylpyrrole-2-carboxylate,98%
  • 2-Methoxycarbonyl-1-methylpyrrole
  • 37619-24-2