(5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID
- Product Name
- (5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID
- CAS No.
- 20876-29-3
- Chemical Name
- (5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID
- Synonyms
- 5-Methoxy-2-nitrobenzeneacetic acid;2-(5-methoxy-2-nitrophenyl)aceticaci;(5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID;Benzeneacetic acid, 5-Methoxy-2-nitro-;(5-Methoxy-2-nitro-phenyl)-acetic acid ,97%
- CBNumber
- CB3416057
- Molecular Formula
- C9H9NO5
- Formula Weight
- 211.17
- MOL File
- 20876-29-3.mol
(5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID Property
- Melting point:
- 176 °C
- Boiling point:
- 404.7±30.0 °C(Predicted)
- Density
- 1.382±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 3.83±0.10(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M219743
- Product name
- 2-(5-Methoxy-2-nitrophenyl)aceticAcid
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CHM0290210
- Product name
- (5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID
- Purity
- 98.00%
- Packaging
- 5MG
- Price
- $502.57
- Updated
- 2021/12/16
- Product number
- 0675AB
- Product name
- 2-(5-Methoxy-2-nitrophenyl)aceticacid
- Packaging
- 250mg
- Price
- $113
- Updated
- 2021/12/16
- Product number
- 0675AB
- Product name
- 2-(5-Methoxy-2-nitrophenyl)aceticacid
- Packaging
- 25g
- Price
- $1108
- Updated
- 2021/12/16
- Product number
- 132365
- Product name
- 2-(5-Methoxy-2-nitrophenyl)aceticacid
- Purity
- 97%
- Packaging
- 10g
- Price
- $1684
- Updated
- 2021/12/16
(5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID Chemical Properties,Usage,Production
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 670, 1955 DOI: 10.1021/ja01608a039
Synthesis
89302-15-8
20876-29-3
General procedure for the synthesis of 2-nitro-5-methoxyphenylacetic acid from 5-methoxy-2-nitrophenylacetonitrile: 1 equivalent of 5-methoxy-2-nitrophenylacetonitrile was dissolved in a mixture of acetic acid (AcOH) and concentrated hydrochloric acid (HCl) (1:5, v/v), and the reaction mixture was heated for 4 hr under reflux conditions. Upon completion of the reaction, the target product 2-nitro-5-methoxyphenylacetic acid was extracted with ethyl acetate and the organic phase was dried with anhydrous sodium sulfate (Na2SO4), followed by removal of solvent by rotary evaporator to give the product.
References
[1] Tetrahedron Letters, 2014, vol. 56, # 1, p. 89 - 94
[2] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 4, p. 1482 - 1496
(5-METHOXY-2-NITRO-PHENYL)-ACETIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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