2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
- Product Name
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
- CAS No.
- 34486-06-1
- Chemical Name
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
- Synonyms
- Picoxystrobin M3;2-Hydroxy-6-(trifL;2-Hydroxy-6-trifluoromethyl;2(1H)-Pyridinone, 6-(trifluor;6-TRIFLUOROMETHYLPYRIDIN-2-ONE;6-(Trifluoromethyl)pyrid-2-one;6-TRIFLUOROMETHYL-PYRIDINE-2-OL;6-(Trifluoromethyl)pyridin-ylol;6-trifluoromethyl-1H-pyridin-2-one;2-HYDROXY-6-TRIFLUOROMETHYLPRIDINE
- CBNumber
- CB3433719
- Molecular Formula
- C6H4F3NO
- Formula Weight
- 163.1
- MOL File
- 34486-06-1.mol
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Property
- Melting point:
- 124-126°
- Boiling point:
- 223.7±40.0 °C(Predicted)
- Density
- 1.398±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 8.03±0.10(Predicted)
- color
- White to Off-White
- InChI
- InChI=1S/C6H4F3NO/c7-6(8,9)4-2-1-3-5(11)10-4/h1-3H,(H,10,11)
- InChIKey
- XXRUAAOADAPPII-UHFFFAOYSA-N
- SMILES
- C1(=O)NC(C(F)(F)F)=CC=C1
- CAS DataBase Reference
- 34486-06-1(CAS DataBase Reference)
- EPA Substance Registry System
- 2(1H)-Pyridinone, 6-(trifluoromethyl)- (34486-06-1)
Safety
- Hazard Codes
- T,Xi
- Risk Statements
- 36/37/38-36-25
- Safety Statements
- 26-36/37/39-45
- RIDADR
- 2811
- HazardClass
- IRRITANT
- PackingGroup
- Ⅲ
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- H977575
- Product name
- 2-Hydroxy-6-trifluoromethylpyridine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- PC9263
- Product name
- 2-Hydroxy-6-(trifluoromethyl)pyridine
- Packaging
- 1g
- Price
- $12
- Updated
- 2021/12/16
- Product number
- J97316
- Product name
- 2-Hydroxy-6-trifluoromethylpyridine
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 024690
- Product name
- 2-Hydroxy-6-(trifluoromethyl)pyridine
- Purity
- 98%
- Packaging
- 1g
- Price
- $18
- Updated
- 2021/12/16
- Product number
- 4H01-3-26
- Product name
- 2-Hydroxy-6-(trifluoromethyl)pyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Chemical Properties,Usage,Production
Uses
2-Hydroxy-6-trifluoromethylpyridine
Synthesis
39890-95-4
34486-06-1
(3) 1500 g of tert-butanol, 140 g of potassium hydroxide and 2-chloro-6-trifluoromethylpyridine prepared in step (2) were added to a 3 L reaction flask, heated up to 70 °C, and the reaction was held for 8 hours. After completion of the reaction, tert-butanol was removed by distillation under reduced pressure, 550 g of ethyl acetate and 550 g of water were added and mixed with stirring. The organic layer was washed with 370 g of saturated brine and dried by adding 100 g of anhydrous sodium sulfate. The ethyl acetate was removed by rotary evaporation to obtain 172.4 g of crude product; (4) The crude product prepared in step (3) was dissolved in 150 g of ethyl acetate, heated to 70 °C and stirred. 1200 g of petroleum ether was added slowly dropwise and the mixture was cooled to 2°C after the dropwise addition was completed, solid crystals were precipitated and the solid was collected by filtration. The solid was washed with 50 g of petroleum ether and dried at 70 °C to give 131.2 g of 2-hydroxy-6-trifluoromethylpyridine as a light yellow solid powder in 80.8% yield.
References
[1] Patent: CN106866512, 2017, A. Location in patent: Paragraph 0014
[2] Patent: US5973159, 1999, A
[3] Patent: CN107759513, 2018, A. Location in patent: Paragraph 0017
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Suppliers
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View Lastest Price from 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE manufacturers
- Product
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE 34486-06-1
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kgs
- Release date
- 2025-09-18
- Product
- 2-Hydroxy-6-trifluoromethylpyridine 34486-06-1
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- Purity: 99%
- Supply Ability
- 1000
- Release date
- 2025-07-18
- Product
- 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE 34486-06-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-10-24