ChemicalBook > CAS DataBase List > 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE

2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE

Product Name
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
CAS No.
34486-06-1
Chemical Name
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
Synonyms
Picoxystrobin M3;2-Hydroxy-6-(trifL;2-Hydroxy-6-trifluoromethyl;2(1H)-Pyridinone, 6-(trifluor;6-TRIFLUOROMETHYLPYRIDIN-2-ONE;6-(Trifluoromethyl)pyrid-2-one;6-TRIFLUOROMETHYL-PYRIDINE-2-OL;6-(Trifluoromethyl)pyridin-ylol;6-trifluoromethyl-1H-pyridin-2-one;2-HYDROXY-6-TRIFLUOROMETHYLPRIDINE
CBNumber
CB3433719
Molecular Formula
C6H4F3NO
Formula Weight
163.1
MOL File
34486-06-1.mol
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2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Property

Melting point:
124-126°
Boiling point:
223.7±40.0 °C(Predicted)
Density 
1.398±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
8.03±0.10(Predicted)
color 
White to Off-White
InChI
InChI=1S/C6H4F3NO/c7-6(8,9)4-2-1-3-5(11)10-4/h1-3H,(H,10,11)
InChIKey
XXRUAAOADAPPII-UHFFFAOYSA-N
SMILES
C1(=O)NC(C(F)(F)F)=CC=C1
CAS DataBase Reference
34486-06-1(CAS DataBase Reference)
EPA Substance Registry System
2(1H)-Pyridinone, 6-(trifluoromethyl)- (34486-06-1)
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Safety

Hazard Codes 
T,Xi
Risk Statements 
36/37/38-36-25
Safety Statements 
26-36/37/39-45
RIDADR 
2811
HazardClass 
IRRITANT
PackingGroup 
Ⅲ
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
H977575
Product name
2-Hydroxy-6-trifluoromethylpyridine
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
024690
Product name
2-Hydroxy-6-(trifluoromethyl)pyridine
Purity
98%
Packaging
5g
Price
$55
Updated
2021/12/16
Apolloscientific
Product number
PC9263
Product name
2-Hydroxy-6-(trifluoromethyl)pyridine
Packaging
1g
Price
$12
Updated
2021/12/16
AK Scientific
Product number
J97316
Product name
2-Hydroxy-6-trifluoromethylpyridine
Packaging
1g
Price
$15
Updated
2021/12/16
Matrix Scientific
Product number
024690
Product name
2-Hydroxy-6-(trifluoromethyl)pyridine
Purity
98%
Packaging
1g
Price
$18
Updated
2021/12/16
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2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Chemical Properties,Usage,Production

Uses

2-Hydroxy-6-trifluoromethylpyridine

Synthesis

39890-95-4

34486-06-1

(3) 1500 g of tert-butanol, 140 g of potassium hydroxide and 2-chloro-6-trifluoromethylpyridine prepared in step (2) were added to a 3 L reaction flask, heated up to 70 °C, and the reaction was held for 8 hours. After completion of the reaction, tert-butanol was removed by distillation under reduced pressure, 550 g of ethyl acetate and 550 g of water were added and mixed with stirring. The organic layer was washed with 370 g of saturated brine and dried by adding 100 g of anhydrous sodium sulfate. The ethyl acetate was removed by rotary evaporation to obtain 172.4 g of crude product; (4) The crude product prepared in step (3) was dissolved in 150 g of ethyl acetate, heated to 70 °C and stirred. 1200 g of petroleum ether was added slowly dropwise and the mixture was cooled to 2°C after the dropwise addition was completed, solid crystals were precipitated and the solid was collected by filtration. The solid was washed with 50 g of petroleum ether and dried at 70 °C to give 131.2 g of 2-hydroxy-6-trifluoromethylpyridine as a light yellow solid powder in 80.8% yield.

References

[1] Patent: CN106866512, 2017, A. Location in patent: Paragraph 0014
[2] Patent: US5973159, 1999, A
[3] Patent: CN107759513, 2018, A. Location in patent: Paragraph 0017

2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE Suppliers

China 251 Europe 1 Germany 3 India 2 United Kingdom 7 United States 18 Global 282
Pure Chemistry Scientific Inc.
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View Lastest Price from 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE 34486-06-1
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kgs
Release date
2025-09-18
Shandong Jihui Chemical Co., Ltd.
Product
2-Hydroxy-6-trifluoromethylpyridine 34486-06-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
Purity: 99%
Supply Ability
1000
Release date
2025-07-18
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE 34486-06-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-24

34486-06-1, 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINERelated Search:

2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE 3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine98%,3-CHLORO-2-HYDROXY-5-(TRIFLUOROMETHYL)PYRIDINE,3-Chloro-2-hydroxy-5-(trifluoromethyl)pyridine 98% N'-HYDROXY-4-(TRIFLUOROMETHYL)PYRIDINE-3-CARBOXIMIDAMIDE 3-Bromo-2-hydroxy-5-(trifluoromethyl)pyridine 98%,3-Bromo-2-hydroxy-5-(trifluoromethyl)pyridine,3-Bromo-2-hydroxy-5-(trifluoromethyl)pyridine98% 2-HYDROXY-4-(TRIFLUOROMETHYL)PYRIDINE 3-Cyano-2-hydroxy-6-(trifluoromethyl)pyridine N'-hydroxy-5-(trifluoromethyl)pyridine-2-carboximidamide 2-Hydroxy-6-(trifluoromethyl)pyridine-3-carboxamide 3-Hydroxy-6-(trifluoromethyl) pyridine 2-Hydroxy-5-(trifluoromethyl)pyridine 97%,2-HYDROXY-5-(TRIFLUOROMETHYL)PYRIDINE,2-Hydroxy-5-(trifluoromethyl)pyridine97% 2-HYDROXY-3-(TRIFLUOROMETHYL)PYRIDINE,2-Hydroxy-3-(trifluoromethyl)pyridine97%,2-Hydroxy-3-(trifluoromethyl)pyridine 97% 2-OXO-6-(TRIFLUOROMETHYL)-1-[4-(TRIFLUOROMETHYL)BENZYL]-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE 1-(2,6-DICHLOROBENZYL)-2-OXO-6-(TRIFLUOROMETHYL)-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE 1-(3,4-DICHLOROBENZYL)-2-OXO-6-(TRIFLUOROMETHYL)-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE 1-(4-CHLOROBENZYL)-2-OXO-6-(TRIFLUOROMETHYL)-1,2-DIHYDRO-3-PYRIDINECARBOXAMIDE 2-Hydroxy-5-trifluoromethyl-pyridine-3-carbaldehyde 3-FLUORO-2-HYDROXY-5-(TRIFLUOROMETHYL)PYRIDINE 3,5-Dibromo-2-hydroxy-6-trifluoromethyl-pyridine

  • 6-TRIFLUOROMETHYLPYRIDIN-2-ONE
  • 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
  • 6-TRIFLUOROMETHYL-PYRIDINE-2-OL
  • 6-trifluoromethyl-1H-pyridin-2-one
  • 2(1H)-Pyridinone, 6-(trifluoromethyl)-
  • 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE
  • 2-HYDROXY-6-TRIFLUOROMETHYLPRIDINE
  • 2-Hydroxy-6-trifluoromethylpyridine 6-Trifluoromethyl-1H-pyridin-2-one
  • 2-Hydroxy-6-(trifloromethyl)pyridine
  • 6-(TrifluoroMethyl)pyridin-2(1H)-one
  • 6-(Trifluoromethyl)pyridin-2-ol, 6-Hydroxy-alpha,alpha,alpha-trifluoro-2-picoline
  • 6-(Trifluoromethyl)pyridin-ylol
  • 2-Hydroxy-6-trifluoromethylpyridine AldrichCPR
  • 2-Hydroxy-6-trifluoromerthylpyridine
  • 2(1H)-Pyridinone, 6-(trifluor
  • Picoxystrobin M3
  • 2-Hydroxy-6-(trifL
  • 2-HYDROXY-6-(TRIFLUOROMETHYL)PYRIDINE ISO 9001：2015 REACH
  • 6-(Trifluoromethyl)pyrid-2-one
  • 6-(Trifluoromethyl)-2(1H)-pyridinone
  • 2-Hyxdroxy-6-(trifluoromethyl)pyridine
  • 12-Hydroxy-6-(trifluoromethyl)pyridine
  • 2-Hydroxy-6-trifluoromethyl
  • 34486-06-1
  • 34486-03-1
  • Building Blocks
  • C6 to C7
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • New Products for Chemical Synthesis
  • Pyridines
  • alcohol
  • Fluorine series
  • john's