Methoxypolyethylene glycol amine

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Methoxypolyethylene glycol amine

Product Name: Methoxypolyethylene glycol amine
CAS No.: 80506-64-5
Chemical Name: Methoxypolyethylene glycol amine
Synonyms: mPEG-NH2;PEG NH2;methoxyPEG amine;mPEG-NH2,MW:1000;AMINOPOLYETHYLENE;mPEG-NH2，M.W. 2000;mPEG-NH2，M.W. 4000;mPEG-amine (MW 550);MPEG-NH2 (Mn= 2,000);mPEG-amine (MW 5000)
CBNumber: CB3442508
Molecular Formula: C5H13NO2
Formula Weight: 119.16222
MOL File: 80506-64-5.mol

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Methoxypolyethylene glycol amine Property

Melting point:: 58-61 °C(lit.)
Flash point:: >110℃
storage temp.: 2-8°C
solubility: Chloroform (Slightly), MEtanol (Slightly)
form: Granular Solid
color: White to off-white
Water Solubility: Soluble in water.
EPA Substance Registry System: Poly(oxy-1,2-ethanediyl), .alpha.-(2-aminoethyl)-.omega.-methoxy- (80506-64-5)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
F: 2-9
TSCA: Yes
HS Code: 39072090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 06679
Product name: Methoxypolyethylene glycol amine
Purity: 5,000, extent of labeling: ≥0.17 mmol/g NH2 loading
Packaging: 1g
Price: $151
Updated: 2024/03/01

Sigma-Aldrich

Product number: 06676
Product name: Methoxypolyethylene glycol amine
Purity: 2,000, extent of labeling: ≥0.4 mmol/g NH2 loading
Packaging: 1g
Price: $306
Updated: 2024/03/01

Alfa Aesar

Product number: 046433
Product name: Methoxypolyethylene glycol amine, M.W. 13,000
Packaging: 1g
Price: $173
Updated: 2024/03/01

Alfa Aesar

Product number: 046433
Product name: Methoxypolyethylene glycol amine, M.W. 13,000
Packaging: 5g
Price: $702.65
Updated: 2024/03/01

Sigma-Aldrich

Product number: 767565
Product name: Poly(ethylene glycol) methyl ether amine
Purity: average Mn 500
Packaging: 1ml
Price: $341
Updated: 2024/03/01

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Methoxypolyethylene glycol amine Chemical Properties,Usage,Production

Description

m-PEG15-amine is a PEG linker containing an amino group and 15 PEG units. It is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

PEG functionalized with amine for ligation and coupling reactions.

Uses

MPEG-NH2 is a reactant in synthesis of pH-sensitive polymeric micelles for intracellular drug delivery.

Uses

Methoxypolyethylene glycol amine is generally used for the chemical modification of biologically active compounds and therapeutic agents. It has been used to increase the aqueous solubility of long-wavelength voltage-sensitive dyes and to prepare the PEG-coated fluorescent beads in studying large-scale rotational cytoplasmic flow.

Application

Methoxypolyethylene glycol amine is used in the reduction of immunogenicity and increasing serum half life.Methoxypolyethylene glycol amine can:
Form dendritic micelles to enhance the solubility of hydrophobic compounds.
Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
PEG functionalized with amine for ligation and coupling reactions.

Methoxypolyethylene glycol amine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methoxypolyethylene glycol amine manufacturers

HebeiShuoshengImportandExportco.,Ltd

Product: AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER 80506-64-5
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000KG/Month
Release date: 2024-08-05

Hebei Longbang Technology Co., Ltd

Product: AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER 80506-64-5
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20TONS
Release date: 2024-05-24

Hebei Jingbo New Material Technology Co., Ltd

Product: Methoxypolyethylene glycol amine 80506-64-5
Price: US $8.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 200000
Release date: 2023-12-28

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