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Methoxypolyethylene glycol amine

Product Name
Methoxypolyethylene glycol amine
CAS No.
80506-64-5
Chemical Name
Methoxypolyethylene glycol amine
Synonyms
mPEG-NH2;PEG NH2;methoxyPEG amine;mPEG-NH2,MW:1000;AMINOPOLYETHYLENE;mPEG-NH2,M.W. 2000;mPEG-NH2,M.W. 4000;mPEG-amine (MW 550);MPEG-NH2 (Mn= 2,000);mPEG-amine (MW 5000)
CBNumber
CB3442508
Molecular Formula
C5H13NO2
Formula Weight
119.16222
MOL File
80506-64-5.mol
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Methoxypolyethylene glycol amine Property

Melting point:
58-61 °C(lit.)
Flash point:
>110℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), MEtanol (Slightly)
form 
Granular Solid
color 
White to off-white
Water Solubility 
Soluble in water.
EPA Substance Registry System
Poly(oxy-1,2-ethanediyl), .alpha.-(2-aminoethyl)-.omega.-methoxy- (80506-64-5)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
2-9
TSCA 
Yes
HS Code 
39072090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
06679
Product name
Methoxypolyethylene glycol amine
Purity
5,000, extent of labeling: ≥0.17 mmol/g NH2 loading
Packaging
1g
Price
$151
Updated
2024/03/01
Sigma-Aldrich
Product number
06676
Product name
Methoxypolyethylene glycol amine
Purity
2,000, extent of labeling: ≥0.4 mmol/g NH2 loading
Packaging
1g
Price
$306
Updated
2024/03/01
Alfa Aesar
Product number
046433
Product name
Methoxypolyethylene glycol amine, M.W. 13,000
Packaging
1g
Price
$173
Updated
2024/03/01
Alfa Aesar
Product number
046433
Product name
Methoxypolyethylene glycol amine, M.W. 13,000
Packaging
5g
Price
$702.65
Updated
2024/03/01
Sigma-Aldrich
Product number
767565
Product name
Poly(ethylene glycol) methyl ether amine
Purity
average Mn 500
Packaging
1ml
Price
$341
Updated
2024/03/01
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Methoxypolyethylene glycol amine Chemical Properties,Usage,Production

Description

m-PEG15-amine is a PEG linker containing an amino group and 15 PEG units. It is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

PEG functionalized with amine for ligation and coupling reactions.

Uses

MPEG-NH2 is a reactant in synthesis of pH-sensitive polymeric micelles for intracellular drug delivery.

Uses

Methoxypolyethylene glycol amine is generally used for the chemical modification of biologically active compounds and therapeutic agents. It has been used to increase the aqueous solubility of long-wavelength voltage-sensitive dyes and to prepare the PEG-coated fluorescent beads in studying large-scale rotational cytoplasmic flow.

Application

Methoxypolyethylene glycol amine is used in the reduction of immunogenicity and increasing serum half life.Methoxypolyethylene glycol amine can:
Form dendritic micelles to enhance the solubility of hydrophobic compounds.
Conjugate with an anticancer drug methotrexate (MTX) to form MTX-PEG with potential application as drug carriers.
Couple with polyethylenimine (PEI) to form graft copolymers which can be used as nonviral gene vectors.
PEG functionalized with amine for ligation and coupling reactions.

Methoxypolyethylene glycol amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Methoxypolyethylene glycol amine Suppliers

SIGMA-RBI
Tel
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Fax
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Country
Switzerland
ProdList
6896
Advantage
91
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View Lastest Price from Methoxypolyethylene glycol amine manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER 80506-64-5
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-05
Hebei Longbang Technology Co., Ltd
Product
AMINOPOLYETHYLENE GLYCOL 5'000 MONOMETHYL ETHER 80506-64-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-05-24
Hebei Jingbo New Material Technology Co., Ltd
Product
Methoxypolyethylene glycol amine 80506-64-5
Price
US $8.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200000
Release date
2023-12-28

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