(+)-PULEGONE

Product Name: (+)-PULEGONE
CAS No.: 89-82-7
Chemical Name: (+)-PULEGONE
Synonyms: PULEGONE;(R)-PULEGONE;PULEGON;P-MENTH-4(8)-EN-3-ONE;2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE;FEMA 2963;NSC 15334;D-PULEGONE;d-Puregone;(+)-PULEONE
CBNumber: CB3448348
Molecular Formula: C10H16O
Formula Weight: 152.23
MOL File: 89-82-7.mol

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(+)-PULEGONE Property

Melting point:: <=25°C
alpha: D20 +21°; 20546 +28.2°
Boiling point:: 224 °C(lit.)
Density: 0.937 g/mL at 25 °C(lit.)
vapor pressure: 138 mm Hg ( 25 °C)
refractive index: n20/D 1.488
FEMA: 2963 | PULEGONE
Flash point:: 185 °F
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), Methanol (Slightly)
form: Liquid
color: Clear colorless to yellow
Specific Gravity: 0.94
Odor: at 100.00 %. peppermint camphor fresh herbal buchu
Odor Type: minty
optical activity: [α]20/D +23.5°, neat
λmax: 255nm(lit.)
Merck: 14,7937
JECFA Number: 753
BRN: 2040703
Dielectric constant: 9.5（20℃）
InChIKey: NZGWDASTMWDZIW-MRVPVSSYSA-N
LogP: 2.56
CAS DataBase Reference: 89-82-7(CAS DataBase Reference)
IARC: 2B (Vol. 108) 2016
EPA Substance Registry System: d-Pulegone (89-82-7)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 23-24/25
RIDADR: 2810
WGK Germany: 3
RTECS: OT0261000
F: 10-23
HS Code: 2914 29 00
HazardClass: 6.1(b)
PackingGroup: III
Hazardous Substances Data: 89-82-7(Hazardous Substances Data)
Toxicity: LD50 orally in Rabbit: 470 mg/kg LD50 dermal Rabbit 3090 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H351Suspected of causing cancer

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W296309
Product name: (R)-(+)-Pulegone
Purity: ≥90%
Packaging: 100g
Price: $132
Updated: 2024/03/01

Sigma-Aldrich

Product number: W296309
Product name: (R)-(+)-Pulegone
Purity: ≥90%
Packaging: 1kg
Price: $968
Updated: 2024/03/01

Sigma-Aldrich

Product number: CRM40371
Product name: (+)-Pulegone solution
Purity: certified reference material, 2000?μg/mL in methanol, ampule of 1?mL
Packaging: 1mL
Price: $82.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.18665
Product name: (R)-(+)-Pulegone
Purity: for synthesis
Packaging: 10ml
Price: $135
Updated: 2024/03/01

Sigma-Aldrich

Product number: 04620590
Product name: (+)-Pulegone
Purity: primary pharmaceutical reference standard
Packaging: 100mg
Price: $384
Updated: 2024/03/01

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(+)-PULEGONE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellow liquid

Chemical Properties

Pulegone.has.a.pleasant.odor,somewhat.similar.to.peppermint.and.camphor.

Occurrence

The l-form is found in the essential oils of Agastache formosana, Israeli orange, Barosma betulina and Barosma crenulata; the d-form is the most abundant and is found in pennyroyal oils. Also reported found in rabbiteye blueberry, black currants (buds), fresh blackberry, heated blackberry, peppermint oil, corn mint oil, spearmint oil, Scotch spearmint oil, other Mentha oils, thyme, black tea, origanum, Ocimum basilicum varieties, rosemary, lemon balm, buchu oil, anise hyssop, sweet grass oil and German chamomile oil.

Uses

A monoterpene, commonly found in the essential oils of Nepeta cataria (Catnip).

Definition

ChEBI: The (5R)-enantiomer of p-menth-4(8)-en-3-one.

Aroma threshold values

Detection:.130.ppb..Aroma.characteristics.at.1.0%:.minty.cooling,.herbal.green,.sweet,.clean.spicy,.with. wintergreen.nuances.

Taste threshold values

Taste characteristics at 20 ppm: minty, terpy, cooling, woody pine, citrus lime, with fresh green peppermint notes.

General Description

(R)-(+)-Pulegone, a monoterpene ketone found in the essential oil of pennyroyal, can induce abortion.

Biochem/physiol Actions

Taste at 20 ppm

Synthesis

Isolated.from.pennyroyal.oil.(Moroccan.or.Spanish);.synthesis.from.3-methyl.cyclohexanone..The.structure.has.been.defined. by.the.work.of.several.authors;.the.d-,.l-.and.dl-forms.are.known;.the.dl-form.is.prepared.synthetically.and.is.not.found.in.nature.

target

GABA Receptor

Purification Methods

Purify pulegone via the semicarbazone which has m 174o (from MeOH) and [] D +68.2o (c 1, CHCl3). Fractionally distil it in vacuo. [Short & Read J Chem Soc 1309 1939]. [Erskine & Waight J Chem Soc 3425 1960, cf Ort Org Synth 65 203 1987, Beilstein 7 III 334, 7 IV 188.]

(+)-PULEGONE Preparation Products And Raw materials

Raw materials

Preparation Products

Menthone p-Mentha-8-thiol-3-one

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(+)-PULEGONE Suppliers

Belgium 1 Canada 1 China 162 France 1 Germany 7 India 5 Japan 5 Spain 1 Switzerland 2 United Kingdom 9 United States 34 USA 1 Global 229

Taizhou Synhigher Biomedical Co., Ltd.

Tel: 0523-86819336; 13357797105
Email: contact@synhigher.com
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
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Email: Sales-CN@TCIchemicals.com
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Energy Chemical

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Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
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Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
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Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
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Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
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View Lastest Price from (+)-PULEGONE manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: (+)-PULEGONE 89-82-7
Price: US $20.00-1.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10 tons
Release date: 2023-11-03

Hebei Mojin Biotechnology Co., Ltd

Product: (+)-PULEGONE 89-82-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-10-09

Hebei Guanlang Biotechnology Co., Ltd.

Product: (+)-PULEGONE 89-82-7
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2023-02-02

89-82-7, (+)-PULEGONERelated Search:

DL-Menthol benzoylpaeoniflorin RehMapicroside Borneol (+)-MENTHOL alpha-Terpineol benzoyloxypaeoniflorin Cantharidin 1,8-Cineole Albiflorin Menthone p-Mentha-8-thiol-3-one S-(-)-PULEGONE Pennyroyal,NLT84%Pulegone,Pennyroyal84%min.Pulegone Z(+)-Pulegone Pulegone semicarbazone (+)-PULEGONE = R-P-MENTH-4(8)-EN-3-ONE trans-Pulegone oxide,cis-Pulegone oxide

(R)-(+)-P-MENTH-4(8)-EN-3-ONE

(R)-P-MENTH-4(8)-EN-3-ONE

(R)-(+)-PULEGONE

(R)-PULEGONE

(R)-(+)-5-METHYL-2-ISOPROPYLIDENCYCLOHEXANONE

(R)-2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE

R-(+)-2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE

PULEGON

(+)-PULEGONE

PULEGONE

PULEGONE, R-(+)-

P-METNH-4(8)-EN-3-ONE

(+)-P-MENTH-4(8)-EN-3-ONE

P-MENTH-4(8)-EN-3-ONE

(r)-(+)-p-menth-4(8)-en-3-on

(r)-cyclohexanon

(+)-1-ISOPROPYLIDENE-4-METHYL-2-CYCLOHEXANONE

2-ISOPROPYLIDENE-5-METHYLCYCLOHEXANONE

(+)-1-METHYL-4-ISOPROPYLIDENE-3-CYCLOHEXANONE

(R)-(+)-PULEGONE, TECH., 85%

(R)-(+)-PULEGONE 85+%

(+)-PULEGONE, TERPENE STANDARD

(+)-4(8)-Para-menthen-3-one

(1R)-(+)-p-Menth-4(8)-en-3-one

Pulegone, pract., 92%

PULEGONE, S-(-)-(SG)

DELTA-PULEGONE

DEXTRO-PULEGONE

R-(+)-PARA-MENTH-4(8)-EN-3-ONE

R-(+)-PULEGONE WITH GC

d-PULEGONE, NATURAL

(+)-Pulegone, (R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one, p-Menth-4(8)-en-3-one

(R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one

(R)-5-Methyl-2-(1-methylethylidene)cyclohexan-1-one

(R)-5-Methyl-2-(1-methylethylidene)cyclohexanone

Pulegone,92%,pract.

PULEGONE, R-(+)-(SG)

(+)-Pulegone ,98%

Pulegone, pract., 92% 100GR

(+)-Pulegone,(R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one

(R)-(+)-Pulegone,(+)-Pulegone, (R)-2-Isopropylidene-5-methylcyclohexanone, (R)-p-Menth-4(8)-en-3-one, p-Menth-4(8)-en-3-one

PULEGONE, TECH

(+)-Pulegone ,90%

(theta)-cyclohexanon

3-Methyl-6-isopropylidenecyclohexanone

4(8)-p-Menthen-3-one

5-methyl-2-(1-methylethylidene)-,(5R)-Cyclohexanone

Cyclohexanone, 5-methyl-2-(1-methylethylidene)-, (R)-

Cyclohexanone,5-methyl-2-(1-methylethylidene)-,(5R)-

Cyclohexanone,5-methyl-2-(1-methylethylidene)-,(R)-

d-p-Menth-4(8)-en-3-one

p-Menth-4(8)-en-3-one, (R)-(+)-

p-Menth-4(8)-en-3-one,(R)-(+)-

Pulegone, (d)

D-PULEGONE

FEMA 2963

(5R)-5-Methyl-2-(1-Methylethylidene)cyclohexanone

NSC 15334