CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE

Product Name: CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE
CAS No.: 370879-56-4
Chemical Name: CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE
Synonyms: CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE;cis-tert-Butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate;(3aR,6aS)-tert-butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate;tert-butyl (3aR,6aS)-2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate;Pyrrolo[3,4-c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-(phenylmethyl)-, 1,1-dimethylethyl ester, (3aR,6aS)-rel-
CBNumber: CB3449709
Molecular Formula: C18H26N2O2
Formula Weight: 302.41
MOL File: 370879-56-4.mol

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CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE Property

Boiling point:: 393.4±35.0 °C(Predicted)
Density: 1.117±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 8.97±0.20(Predicted)
Appearance: Colorless to light yellow Liquid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FB148772
Product name: cis-5-Benzyl-2-boc-hexahydropyrrolo[3,4-c]pyrrole
Packaging: 100mg
Price: $197
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148772
Product name: cis-5-Benzyl-2-boc-hexahydropyrrolo[3,4-c]pyrrole
Packaging: 25mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148772
Product name: cis-5-Benzyl-2-boc-hexahydropyrrolo[3,4-c]pyrrole
Packaging: 50mg
Price: $113
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148772
Product name: cis-5-Benzyl-2-boc-hexahydropyrrolo[3,4-c]pyrrole
Packaging: 250mg
Price: $395
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB148772
Product name: cis-5-Benzyl-2-boc-hexahydropyrrolo[3,4-c]pyrrole
Packaging: 500mg
Price: $685
Updated: 2021/12/16

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CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE Chemical Properties,Usage,Production

Synthesis

172739-04-7

24424-99-5

370879-56-4

To a solution of (3aR,6aS)-2-benzyl octahydropyrrolo[3,4-c]pyrrole (10 g, 49.5 mmol) in tetrahydrofuran (THF, 100 mL) was sequentially added N,N-diisopropylethylamine (DIPEA, 12.8 g, 99 mmol) and di-tert-butyl dicarbonate (Boc2O, 10.8 g, 49.5 mmol). The reaction mixture was stirred at room temperature for 5 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate and washed sequentially with water, saturated sodium bicarbonate (NaHCO3) solution and saturated saline. The organic layer was dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to afford tert-butyl (3aR,6aS)-5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate as a yellow oil (12 g, 80%).

References

[1] Patent: WO2015/120049, 2015, A1. Location in patent: Page/Page column 139
[2] Patent: WO2016/191172, 2016, A1. Location in patent: Page/Page column 85
[3] Patent: US2002/19388, 2002, A1
[4] Patent: US2009/281118, 2009, A1. Location in patent: Page/Page column 10
[5] Journal of Medicinal Chemistry, 2009, vol. 52, # 14, p. 4126 - 4141

CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE Preparation Products And Raw materials

Raw materials

Preparation Products

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CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE Suppliers

China 17 India 1 Switzerland 1 United Kingdom 3 United States 6 Global 28

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370879-56-4, CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLERelated Search:

3-Benzyl-3,7-diazabicyclo[3.3.0]octane 2-BOC-HEXAHYDRO-PYRROLO[3,4-C]PYRROLE Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI) cis-2-Boc-hexahydropyrrolo[3,4-c]pyrrole (R)-N-Boc-3-(aminomethyl)pyrrolidine (R)-1-BENZYL-3-N-BOC-AMINOMETHYL PYRROLIDINE (R)-1-Boc-3-((dimethylamino)methyl)pyrrolidine (S)-1-BENZYL-3-N-BOC-AMINOMETHYLPYRROLIDINE (R)-1-Boc-3-(aminomethyl)pyrrolidine 3-Boc-aminomethylpyrrolidine 1-Benzyl-3-Boc-aminomethylpyrrolidine CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE (S)-1-BOC-3-((DIMETHYLAMINO)METHYL)PYRROLIDINE (S)-3-AMINOMETHYL-1-BENZYLPYRROLIDINE 1-BOC-3-(ETHYLAMINOMETHYL)-PYRROLIDINE (3R)-3-Aminomethyl-1-benzylpyrrolidine C-(1-BENZYL-PYRROLIDIN-3-YL)-METHYLAMINE

CIS-5-BENZYL-2-BOC-HEXAHYDROPYRROLO[3,4-C]PYRROLE

cis-tert-Butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

(3aR,6aS)-tert-butyl 5-benzylhexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

tert-butyl (3aR,6aS)-2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrole-5-carboxylate

Pyrrolo[3,4-c]pyrrole-2(1H)-carboxylic acid, hexahydro-5-(phenylmethyl)-, 1,1-dimethylethyl ester, (3aR,6aS)-rel-

370879-56-4

C18H26N2O2

pharmacetical