Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI)
- Product Name
- Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI)
- CAS No.
- 173340-26-6
- Chemical Name
- Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI)
- Synonyms
- (S)-3-(Boc-aminomethyl)py...;(S)-tert-butyl pyrrolidin-3-ylmethylcarbamate;tert-butyl ((S)-pyrrolidin-3-yl)MethylcarbaMate;tert-butyl N-[(3S)-pyrrolidin-3-ylmethyl]carbamate;(S)-3-N-Boc-aminomethyl pyrrolidine, CAS 173340-26-6;Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl es...;(S)-(3-Pyrrolidinylmethyl)-carbamic acid 1,1-dimethylethyl ester;Carbamic acid, N-[(3S)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester;Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI)
- CBNumber
- CB31051644
- Molecular Formula
- C10H20N2O2
- Formula Weight
- 200.28
- MOL File
- 173340-26-6.mol
Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI) Property
- Boiling point:
- 303.9±15.0 °C(Predicted)
- Density
- 0.997
- storage temp.
- 2-8°C(protect from light)
- pka
- 12.71±0.46(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- B124263
- Product name
- (S)-tert-butylpyrrolidin-3-ylmethylcarbamate
- Packaging
- 500mg
- Price
- $265
- Updated
- 2021/12/16
- Product number
- FB144351
- Product name
- (S)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate
- Packaging
- 500mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB144351
- Product name
- (S)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate
- Packaging
- 1g
- Price
- $140
- Updated
- 2021/12/16
- Product number
- AS51128
- Product name
- (S)-3-(N-Boc-aminomethyl)pyrrolidine
- Purity
- 95+% ee
- Packaging
- 1g
- Price
- $214
- Updated
- 2021/12/16
- Product number
- 070421
- Product name
- (S)-Pyrrolidin-3-ylmethyl-carbamic acid tert-butyl ester
- Purity
- 97%
- Packaging
- 1g
- Price
- $225
- Updated
- 2021/12/16
Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI) Chemical Properties,Usage,Production
Synthesis
173340-24-4
173340-26-6
General procedure for the synthesis of (S)-3-N-Boc-aminomethylpyrrolidine from (3R)-1-[(1S)-1-phenylethyl]-3-pyrrolidinylmethyl]carbamic acid,1,1-dimethylethyl ester (9CI): tert-butyl [1-(1-phenylethyl)-pyrrolidin-3-ylmethyl]-carbamate (3.50 g, 11.5 mmol) was dissolved in methanol in methanol, 20% Pd/C catalyst was added and the hydrogenation reaction was carried out under hydrogen pressure of 50 psi.After 24 h, the reaction mixture was filtered and concentrated to afford 1.75 g (S)-3-N-Boc-aminomethylpyrrolidine (yield: 76%). Mass spectrometry analysis (APCI+): m/z 201 ([M+H]+).
References
[1] Patent: WO2005/49602, 2005, A1. Location in patent: Page/Page column 88; 89; 124
[2] Patent: WO2005/49605, 2005, A1. Location in patent: Page/Page column 116; 117; 152
Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Carbamic acid, (3-pyrrolidinylmethyl)-, 1,1-dimethylethyl ester, (S)- (9CI) manufacturers
- Product
- (S)-tert-Butyl (pyrrolidin-3-ylmethyl)carbamate 173340-26-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-09