FOLIC ACID DIHYDRATE
- Product Name
- FOLIC ACID DIHYDRATE
- CAS No.
- 75708-92-8
- Chemical Name
- FOLIC ACID DIHYDRATE
- Synonyms
- FolicAcidB.P.;PGA DIHYDRATE;FOLIC ACID pure;FOLIC ACID DIHYDRATE;PTEROYLGLUTAMIC ACID;FOLIC ACID, 500MG, NEAT;VitaMin M or VitaMin Bc;FOLIC ACID DIHYDRATE 97%;PGA, Pteroylglutamic acid;PTEROYLGLUTAMIC ACID DIHYDRATE
- CBNumber
- CB3453412
- Molecular Formula
- C19H23N7O8
- Formula Weight
- 477.43
- MOL File
- 75708-92-8.mol
FOLIC ACID DIHYDRATE Property
- Melting point:
- 250°C
- storage temp.
- Store at RT.
- solubility
- Aqueous Acid (Slightly), Aqueous Base (Slightly), DMSO (Slightly)
- pka
- pK1:8.26 (25°C)
- form
- Solid
- color
- Yellow to Dark Yellow
- Water Solubility
- Miscible with water.
- Merck
- 14,4221
- BRN
- 100781
- CAS DataBase Reference
- 75708-92-8
Safety
- WGK Germany
- 3
- RTECS
- LP5425000
- TSCA
- Yes
N-Bromosuccinimide Price
- Product number
- A14300
- Product name
- Folic acid dihydrate, 97%
- Packaging
- 25g
- Price
- $67.65
- Updated
- 2024/03/01
- Product number
- A14300
- Product name
- Folic acid dihydrate, 97%
- Packaging
- 100g
- Price
- $231
- Updated
- 2024/03/01
- Product number
- F680328
- Product name
- FolicAcidDihydrate
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 01422
- Product name
- Folicaciddihydrate,97.0-102.0%(Assay),meetsUSPspecifications
- Purity
- 97.0-102.0%(Assay)
- Packaging
- 250G
- Price
- $104.83
- Updated
- 2021/12/16
- Product number
- 01422
- Product name
- Folic acid dihydrate
- Purity
- 97.0-102.0% (Assay)
- Packaging
- 1KG
- Price
- $260
- Updated
- 2021/12/16
FOLIC ACID DIHYDRATE Chemical Properties,Usage,Production
Chemical Properties
Yellow to yellow-orange crystalline powd
Uses
Vitamin B9. A B-complex vitamin necessary for the body to produce red blood cellsFolic acid dehydrate is used to form non-covalent complexes with polyethylenimine. It is used for the delivery of genes, which finds application in gene therapy. It is a B-complex vitamin, which is necessary for the body to produce red blood cells.
Purification Methods
If paper chromatography indicates impurities, then recrystallise it from hot H2O or from dilute acid [Walker et al. J Am Chem Soc 70 19 1948]. Impurities may be removed by repeated extraction with n-BuOH of a neutral aqueous solution of folic acid (by suspending in H2O and adding N NaOH dropwise till the solid dissolves, then adjusting the pH to ~7.0-7.5) followed by precipitation with acid, filtration, or better collected by centrifugation and recrystallised form hot H2O. [Blakley Biochem J 65 331 1975, Kalifa et al. Helv Chim Acta 6 1 2739 1978.] Chromatography on cellulose followed by filtration through charcoal has also been used to obtain pure acid. [Sakami & Knowles Science 129 274 1959.] UV: max 247 and 296nm ( 12,800 and 18,700) in H2O pH 1.0; 282 and 346nm ( 27.600 and 7,200) in H2O pH 7.0; 256, 284 and 366nm ( 24600, 24,500 and 86,00) in H2O pH 13 [Rabinowitz in The Enzymes (Boyer et al. Eds), 2 185 1960]. [Beilstein 26 III/IV 3944.]
FOLIC ACID DIHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
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