3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide

Product Name: 3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide
CAS No.: 26723-60-4
Chemical Name: 3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide
Synonyms: 3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol;3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-...;3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-ol;3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide;3-CHLORO-6,11-DIHYDRO-5,5-DIOXO-11-HYDROXY-6-METHYLDIBENZO[C,F][1,2]THIAZEPINE;Dibenzo[c,f][1,2]thiazepin-11-ol, 3-chloro-6,11-dihydro-6-methyl-, 5,5-dioxide;3-Chloro-6,11-dihydro-6-methyl-11-hydroxydibenzo[c,f][1,2]thiazepine 5,5-dioxide;3-Chloro-11-hydroxy-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepine 5,5-dioxide
CBNumber: CB3455067
Molecular Formula: C14H12ClNO3S
Formula Weight: 309.77
MOL File: 26723-60-4.mol

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3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide Property

Melting point:: 196-198°C
Boiling point:: 482.8±55.0 °C(Predicted)
Density: 1.472±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 12.60±0.20(Predicted)
color: White
Water Solubility: 30mg/L at 25℃
LogP: 2.78

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: C374795
Product name: 3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine
Packaging: 100mg
Price: $1110
Updated: 2021/12/16

AK Scientific

Product number: X0078
Product name: 3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine
Packaging: 100g
Price: $1190
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0027747
Product name: 3-CHLORO-6,11-DIHYDRO-5,5-DIOXO-11-HYDROXY-6-METHYLDIBENZO[C,F][1,2]THIAZEPINE
Purity: 95.00%
Packaging: 10G
Price: $1531.53
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC140279
Product name: 3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine
Packaging: 10g
Price: $161.3
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC140279
Product name: 3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine
Packaging: 5G
Price: $93
Updated: 2021/12/16

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3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide Chemical Properties,Usage,Production

Uses

3-Chloro-6,11-dihydro-5,5-dioxo-11-hydroxy-6-methyldibenzo[c,f][1,2]thiazepine, can beused in the synthesis of Dibenzo[c,f][1,2]thiazepine derivatives.

Synthesis

26638-53-9

26723-60-4

The general procedure for the synthesis of 3-chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepin-11(6H)-one 5,5-dioxide from 3-chloro-6-methyl-dibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide was as follows: to a solution of 3-chloro-6-methyl-dibenzo[c,f][1,2]thiazepin- 11(6H)-one 5,5-dioxide (62.5 g) to a solution of methanol (500 ml), sodium borohydride (15.04 g) was slowly added at 0-5 °C. The reaction mixture was stirred at 0-5 °C for 30 min, followed by continued stirring at room temperature for 30-60 min. After completion of the reaction, the solid product was collected by filtration and washed with methanol. The resulting solid was dried under constant weight to afford 3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide in 90-95% yield.

References

[1] Patent: WO2010/70667, 2010, A2. Location in patent: Page/Page column 5
[2] Journal of Medicinal Chemistry, 1992, vol. 35, # 13, p. 2481 - 2496

3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide Preparation Products And Raw materials

Raw materials

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3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide Suppliers

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View Lastest Price from 3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide manufacturers

Career Henan Chemical Co

Product: 3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-ol 26723-60-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-25

26723-60-4, 3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxideRelated Search:

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3-CHLORO-6,11-DIHYDRO-5,5-DIOXO-11-HYDROXY-6-METHYLDIBENZO[C,F][1,2]THIAZEPINE

3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol 5,5-dioxide

3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-ol

3-Chloro-11-hydroxy-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepine 5,5-dioxide

3-chloro-6-methyl-5,5-dioxo-11H-benzo[c][2,1]benzothiazepin-11-ol

3-Chloro-6,11-dihydro-6-methyl-11-hydroxydibenzo[c,f][1,2]thiazepine 5,5-dioxide

Dibenzo[c,f][1,2]thiazepin-11-ol, 3-chloro-6,11-dihydro-6-methyl-, 5,5-dioxide

3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-...

26723-60-4

26623-60-4

C14H12CINO3S