ChemicalBook > CAS DataBase List > 8-HYDROXYOCTANOIC ACID

8-HYDROXYOCTANOIC ACID

Product Name
8-HYDROXYOCTANOIC ACID
CAS No.
764-89-6
Chemical Name
8-HYDROXYOCTANOIC ACID
Synonyms
8-hydroxyoctanoate;8-HYDROXYOCTANSURE;8-hydroxyoctanoicaci;8-HYDROXYCAPRYLIC ACID;8-HYDROXYOCTANOIC ACID;Octanoic acid, 8-hydroxy-;8-Hydroxyoctanoic acid,90%;8-Hydroxyoctanoic acid 98% (T)
CBNumber
CB3458316
Molecular Formula
C8H16O3
Formula Weight
160.21
MOL File
764-89-6.mol
More
Less

8-HYDROXYOCTANOIC ACID Property

Melting point:
59-63 °C
Boiling point:
130°C/1mm
Density 
1.0227 (rough estimate)
refractive index 
1.4370 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
pka
4.77±0.10(Predicted)
form 
crystalline powder
color 
White
BRN 
1237092
LogP
0.900 (est)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
10-21
HS Code 
2918199890
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
55999
Product name
8-Hydroxyoctanoic acid
Purity
98% (T)
Packaging
100mg
Price
$103
Updated
2023/01/07
TCI Chemical
Product number
H1818
Product name
8-Hydroxyoctanoic Acid
Purity
min. 98.0 %
Packaging
250MG
Price
$64
Updated
2025/07/31
TCI Chemical
Product number
H1818
Product name
8-Hydroxyoctanoic Acid
Purity
min. 98.0 %
Packaging
1G
Price
$159
Updated
2025/07/31
TRC
Product number
H950885
Product name
8-Hydroxyoctanoic acid
Packaging
2.5g
Price
$160
Updated
2021/12/16
Matrix Scientific
Product number
004853
Product name
8-Hydroxyoctanoic acid
Purity
95%
Packaging
1g
Price
$132
Updated
2021/12/16
More
Less

8-HYDROXYOCTANOIC ACID Chemical Properties,Usage,Production

Chemical Properties

light yellow powder

Uses

8-Hydroxyoctanoic Acid is an intermediate in the synthesis of mono-carboxy-isooctyl-phthalate (M525590). 8-Hydroxyoctanoic Acid is also used as a reagent in the synthesis of histone deacetylases (HDAC) inhibitors with an N-formyl hydroxylamine head group which are promising targets for cancer chemotherapy.

Definition

ChEBI: An omega-hydroxy fatty acid that is caprylic acid in which one of the hydrogens of the terminal methyl group is replaced by a hydroxy group.

General Description

8-Hydroxyoctanoic acid is one of the constituents of ‘‘Royal jelly′′ acid found in herbhoneys and genuine honeys.

Synthesis

629-41-4

764-89-6

GENERAL PROCEDURE: All catalytic activity testing experiments were carried out in Schlenk tubes (50 mL) equipped with a condenser. 8-Hydroxycaprylic acid (HCA) was prepared by HDO oxidation reaction in alkaline aqueous medium using H2O2 as oxidant. The typical reaction procedure was as follows: first, the aliphatic diol (0.5 mmol) was weighed and dispersed with catalyst (25 mg) in deionized water (3.5 mL) in a Schlenk tube. Subsequently, 30% H2O2 (0.75 mL) and 0.5 M NaOH (0.75 mL) were added to the above mixture. The Schlenk tubes were placed in an oil bath preheated to 353 K and reacted for different time intervals under continuous magnetic stirring (500 rpm). After completion of the reaction, a portion of the reaction solution was taken and diluted 20-fold with 10 mM aqueous H2SO4 and the catalyst was removed by passing it through a 0.20 μm filter (Milex-LG). The resulting filtrate was analyzed by high performance liquid chromatography (HPLC, WATERS 600) on an Aminex HPX-87H column (Bio-Rad Laboratories, Inc.) with a refractive index detector. An aqueous solution of 10 mM H2SO4 was used as the eluent at a flow rate of 0.5 mL/min, and the column temperature was maintained at 323 K. The conversion and yield were determined by the calibration curve method for commercial products.

References

[1] Catalysis Today, 2016, vol. 265, p. 231 - 239

8-HYDROXYOCTANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

8-HYDROXYOCTANOIC ACID Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11598
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2150
Advantage
55
Hangzhou Sage Chemical Co., Ltd.
Tel
+86057186818502 13588463833
Fax
Pls mail us for more information!
Email
info@sagechem.com
Country
China
ProdList
10266
Advantage
58
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
More
Less

View Lastest Price from 8-HYDROXYOCTANOIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
8-Hydroxyoctanoic acid 764-89-6
Price
US $2.20-8.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
50kg
Release date
2025-06-24
PNP Biotech Co. Ltd
Product
8-Hydroxyoctanoic acid 764-89-6
Price
US $0.00/KG
Min. Order
25KG
Purity
95%
Supply Ability
Inquiry
Release date
2022-09-28
Honest Joy Holdings Limited
Product
8-hydroxyoctanoicacid 764-89-6
Price
US $0.00/KG
Min. Order
1KG
Purity
97.5%
Supply Ability
100 tons
Release date
2022-01-14

764-89-6, 8-HYDROXYOCTANOIC ACIDRelated Search:


  • 8-HYDROXYOCTANOIC ACID
  • 8-HYDROXYCAPRYLIC ACID
  • 8-hydroxyoctanoate
  • 8-HYDROXYOCTANSURE
  • 8-Hydroxyoctanoic acid,90%
  • Octanoic acid, 8-hydroxy-
  • 8-Hydroxyoctanoic acid 98% (T)
  • 8-hydroxyoctanoicaci
  • 764-89-6
  • C8H16O3
  • Organic Building Blocks
  • Building Blocks
  • Carbonyl Compounds
  • Carboxylic Acids
  • C8
  • Building Blocks
  • C8
  • Carbonyl Compounds
  • Carboxylic Acids
  • Chemical Synthesis
  • Organic Building Blocks