ChemicalBook > CAS DataBase List > (R)-(+)-Tetrahydro-2-furoic acid

(R)-(+)-Tetrahydro-2-furoic acid

Product Name
(R)-(+)-Tetrahydro-2-furoic acid
CAS No.
87392-05-0
Chemical Name
(R)-(+)-Tetrahydro-2-furoic acid
Synonyms
(R)-TETRAHYDROFURAN-2-CARBOXYLIC ACID;R-TETRAHYDRO-2-FUROIC ACID;R-THFC;BAL THF ACID;RARECHEM AL BO 2359;Faropenem side chain;Baloxavir Impurity 43;R(+)-2-Tetrahydrofuroic;Faropenem Intermediates;(R)-2-TETRAHYDROFUROIC ACID
CBNumber
CB3465646
Molecular Formula
C5H8O3
Formula Weight
116.12
MOL File
87392-05-0.mol
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(R)-(+)-Tetrahydro-2-furoic acid Property

Boiling point:
128-129 °C13 mm Hg(lit.)
alpha 
+19.6±0.2°(neat) (D/20℃)
Density 
1.209 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.46(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
clear liquid
pka
3.60±0.20(Predicted)
color 
Colorless to Light yellow
optical activity
[α]23/D +4°, c = 1 in methanol
BRN 
4658739
InChI
InChI=1S/C5H8O3/c6-5(7)4-2-1-3-8-4/h4H,1-3H2,(H,6,7)/t4-/m1/s1
InChIKey
UJJLJRQIPMGXEZ-SCSAIBSYSA-N
SMILES
O1CCC[C@@H]1C(O)=O
CAS DataBase Reference
87392-05-0(CAS DataBase Reference)
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Safety

Hazard Codes 
C,Xi
Risk Statements 
22-34-36/37/38
Safety Statements 
26-36/37/39-45-36
RIDADR 
UN 3265 8/PG 3
WGK Germany 
3
HazardClass 
8
PackingGroup 
III
HS Code 
29321900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
479292
Product name
(R)-(+)-Tetrahydro-2-furoic acid
Purity
99%
Packaging
5g
Price
$161
Updated
2024/03/01
TCI Chemical
Product number
T1740
Product name
(R)-(+)-Tetrahydrofuran-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$126
Updated
2024/03/01
TCI Chemical
Product number
T1740
Product name
(R)-(+)-Tetrahydrofuran-2-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$379
Updated
2024/03/01
Alfa Aesar
Product number
L19410
Product name
(R)-(+)-Tetrahydro-2-furoic acid, 98+%, ee 98%
Packaging
1g
Price
$35.65
Updated
2024/03/01
Alfa Aesar
Product number
L19410
Product name
(R)-(+)-Tetrahydro-2-furoic acid, 98+%, ee 98%
Packaging
5g
Price
$102.65
Updated
2024/03/01
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(R)-(+)-Tetrahydro-2-furoic acid Chemical Properties,Usage,Production

Description

(R)-(+)-2-Tetrahydrofuroic acid is an important pharmaceutical intermediate compound used in the preparation of β-lactam antibiotics (Faropenem sodium), influenza antiviral drugs (Baloxavir Marboxil), hypertension drugs (Terazosin), and anticancer drugs.

Chemical Properties

Colorless to light yellow liquid

Uses

(R)-(+)-2-Tetrahydrofuroic acid is a heterocyclic derivative and can be used as a pharmaceutical intermediate.

(R)-(+)-Tetrahydro-2-furoic acid Preparation Products And Raw materials

Raw materials

acetonitrile Acetone BRUCINE DIHYDRATE Sodium sulfate Sodium chloride Chromium(VI) oxide Tetrahydrofurfuryl alcohol Diethyl ether Ethyl acetate

Preparation Products

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(R)-(+)-Tetrahydro-2-furoic acid Suppliers

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View Lastest Price from (R)-(+)-Tetrahydro-2-furoic acid manufacturers

Hubei Lidu New Material Technology Co., Ltd
Product
(R)-(+)-Tetrahydro-2-furoic acid 87392-05-0
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
20tons
Release date
2024-10-30
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(R)-(+)-2-Tetrahydrofuroic acid 87392-05-0
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
5000kg/month
Release date
2021-12-27
Hebei Weibang Biotechnology Co., Ltd
Product
Afatinib (BIBW 2992) 439081-18-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-11

87392-05-0, (R)-(+)-Tetrahydro-2-furoic acidRelated Search:

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  • 87392-05-0
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  • CARBOXYLIC ACID
  • Asymmetric Synthesis
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