IDRA 21
- Product Name
- IDRA 21
- CAS No.
- 22503-72-6
- Chemical Name
- IDRA 21
- Synonyms
- AMPAKINE;DRA 21;IDRA 21;IDRA 21,98%;S-18986 IDRA-21 AMPAKINE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE;7-chloro-3-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-...;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE S,S-DIOXIDE;7-CHLORO-3-METHYL-3,4-DIHYDRO-2H-1,2,4-BENZOTHIADIAZINE 1,1-DIOXIDE;7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
- CBNumber
- CB3468324
- Molecular Formula
- C8H9ClN2O2S
- Formula Weight
- 232.69
- MOL File
- 22503-72-6.mol
IDRA 21 Property
- Melting point:
- 209 °C(Solv: acetic acid (64-19-7))
- Boiling point:
- 405.1±55.0 °C(Predicted)
- Density
- 1.394±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly), Methanol (Slightly, Sonicated)
- form
- Solid
- pka
- 9.78±0.40(Predicted)
- color
- Off-White to Pale Yellow
- InChIKey
- VZRNTCHTJRLTMU-UHFFFAOYSA-N
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- I5773
- Product name
- IDRA 21
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $210
- Updated
- 2024/03/01
- Product number
- 1219
- Product name
- IDRA 21
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $183
- Updated
- 2021/12/16
- Product number
- 1219
- Product name
- IDRA 21
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $770
- Updated
- 2021/12/16
- Product number
- 255490
- Product name
- IDRA 21
- Packaging
- 10mg
- Price
- $423
- Updated
- 2021/12/16
- Product number
- I232500
- Product name
- IDRA 21
- Packaging
- 250mg
- Price
- $1540
- Updated
- 2021/12/16
IDRA 21 Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline powder
Uses
IDRA-21 is a benzothiadiazine derivative and a positive allosteric modulator of glutamate AMPA receptors (1,2,3,4). It is able to increase excitatory synaptic strength by inhibiting AMPA receptor desensitization. IDRA 21 may exhibit therapeutic effects to ameliorate memory deficits in patients with cognitive impairments such as Alzheimer''s disease.
Uses
IDRA-21 inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).
Definition
ChEBI: 7-chloro-3-methyl-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine 1,1-dioxide is a benzothiadiazine.
Biological Activity
Inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. More able to cross the blood-brain barrier than cyclothiazide (6-Chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiazidiazine-7-sulfonamide-1,1-dioxide ).
storage
Room temperature
IDRA 21 Preparation Products And Raw materials
Raw materials
Preparation Products
IDRA 21 Suppliers
- Tel
- --
- Fax
- --
- sales@chemos-group.com
- Country
- Germany
- ProdList
- 6350
- Advantage
- 71
View Lastest Price from IDRA 21 manufacturers
- Product
- IDRA21 22503-72-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99.0%min. HPLC
- Supply Ability
- 1000kg
- Release date
- 2022-11-08
- Product
- Idra-21 22503-72-6
- Price
- US $150.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2024-11-29
- Product
- IDRA 21 22503-72-6
- Price
- US $12.00-10.00/Grams
- Min. Order
- 50Grams
- Purity
- 99.99%
- Supply Ability
- 100Tons
- Release date
- 2023-03-17