HUMAN VEGF165
Description Source Background- Product Name
- HUMAN VEGF165
- CAS No.
- 127464-60-2
- Chemical Name
- HUMAN VEGF165
- Synonyms
- VPF;VEGF;MVCD1;mVEGF;RHVPF;RHVEGF;Vegf188;VEGF112;L VEGFA;MGC70609
- CBNumber
- CB3470679
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
HUMAN VEGF165 Property
- storage temp.
- -20°C
- form
- powder
- color
- white
- biological source
- rat
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- V7259
- Product name
- Vascular Endothelial Growth Factor human
- Purity
- VEGF, recombinant, expressed in E. coli, powder, suitable for cell culture
- Packaging
- 10μg
- Price
- $225
- Updated
- 2025/07/31
- Product number
- V3388
- Product name
- Vascular Endothelial Growth Factor (aa 207-318) human
- Purity
- ≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder
- Packaging
- 5μG
- Price
- $672.49
- Updated
- 2025/07/31
- Product number
- SRP4365
- Product name
- VEGF165 from rat
- Purity
- recombinant, expressed in E. coli, ≥98% (SDS-PAGE)
- Packaging
- 10μG
- Price
- $356
- Updated
- 2025/07/31
- Product number
- SRP3182
- Product name
- VEGF human
- Purity
- Animal-component free, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
- Packaging
- 10μG
- Price
- $439
- Updated
- 2025/07/31
- Product number
- SAB2502119
- Product name
- Anti-VEGFA antibody produced in goat
- Purity
- affinity isolated antibody, buffered aqueous solution
- Packaging
- 100μG
- Price
- $586
- Updated
- 2025/07/31
HUMAN VEGF165 Chemical Properties,Usage,Production
Uses
VEGF human has been used as a chemoattractant for HUVECs (human umbilical vein endothelial cells) migration assay.
General Description
VEGF (vascular endothelial growth factor) signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant human VEGF is a 38.2kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.
Biochem/physiol Actions
VEGF (vascular endothelial growth factor) is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intraocular neovascular syndromes. Polymorphism in VEGF at C(-634)G is linked with diabetic retinopathy in type 2 diabetes.
Description
Vascular Endothelial Growth Factor Human Recombinant produced in E.Coli is a double, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 38.2kDa.
The VEGF is purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Vascular endothelial growth factor (VEGF) is an important signaling protein involved in vessel formation As its name implies, VEGF activity has been mostly studied on cells of the vascular endothelium, although it does have effects on a number of other cell types (e.g. stimulation monocyte/macrophage migration, neurons, cancer cells, kidney epithelial cells ). VEGF mediates increased vascular permeability, induces vasculogenesis and endothelial cell production, promotes cell migration, and inhibits apoptosis. In vitro, VEGF has been shown to stimulate endothelial cell mitogenesis and cell migration. VEGF is also a vasodilator and increases microvascular permeability and was originally referred to as vascular permeability factor. VEGF is located in normal cartilage though only osteoarthritic cartilage expresses the VEGF receptors, NP1, VEGFR1 and VEGFR2. The VEGF level in the culture media from OA chondrocytes was more than 3 folds higher than in media from normal chondrocytes
HUMAN VEGF165 Preparation Products And Raw materials
Raw materials
Preparation Products
HUMAN VEGF165 Suppliers
- Tel
- --
- Fax
- --
- jaeger@biotrend.com
- Country
- Germany
- ProdList
- 6115
- Advantage
- 76