5-NITRO-2-FUROYL CHLORIDE

Product Name: 5-NITRO-2-FUROYL CHLORIDE
CAS No.: 25084-14-4
Chemical Name: 5-NITRO-2-FUROYL CHLORIDE
Synonyms: Ai3-23633;Einecs 246-607-6;5-nitrofuroyl chloride;5-NITRO-2-FUROYL CHLORIDE;2-Furoyl chloride, 5-nitro-;5-Nitro-2-furancarbonyl chloride;5-NITROFURAN-2-CARBONYL CHLORIDE;2-Furancarbonyl chloride, 5-nitro-;5-nitrofuran-2-carboxylic chloride;N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide
CBNumber: CB3470912
Molecular Formula: C5H2ClNO4
Formula Weight: 175.53
MOL File: 25084-14-4.mol

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5-NITRO-2-FUROYL CHLORIDE Property

Melting point:: 34-41 °C
Boiling point:: 137-140°C 15mm
Density: 1.588±0.06 g/cm3(Predicted)
Flash point:: 137-140°C/15mm
Sensitive: Moisture Sensitive
BRN: 139693
CAS DataBase Reference: 25084-14-4(CAS DataBase Reference)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: 3261
WGK Germany: 3
Hazard Note: Corrosive
HazardClass: 8
PackingGroup: II
HS Code: 2932190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 683752
Product name: 5-Nitro-2-furoyl chloride
Purity: 95%
Packaging: 5g
Price: $224
Updated: 2024/03/01

Sigma-Aldrich

Product number: 683752
Product name: 5-Nitro-2-furoyl chloride
Purity: 95%
Packaging: 25g
Price: $908
Updated: 2023/06/20

TRC

Product number: N493865
Product name: 5-Nitro-2-furoyl chloride
Packaging: 5g
Price: $330
Updated: 2021/12/16

TRC

Product number: N493865
Product name: 5-Nitro-2-furoyl chloride
Packaging: 2.5g
Price: $240
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H54-5-Z8
Product name: 5-Nitrofuran-2-carbonyl chloride
Packaging: 5G
Price: $226
Updated: 2021/12/16

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5-NITRO-2-FUROYL CHLORIDE Chemical Properties,Usage,Production

Description

5-Nitrofuroyl chloride is a furan chain bound to an acyl and a nitro group. Nitrofuran derivatives have been used as antibiotic and antimicrobial drugs but the acyl group bound to furan (furoyl chloride) is an intermediate for the synthesis of pharmaceuticals (e.g. antibiotics). 5-Nitrofuroyl chloride has been used as a reagent for the synthesis of some compounds with antibacterial properties and other chemicals.

Uses

5-Nitrofuroyl chloride has been used in the synthesis of certain ureides of furanmonocarboxylic acid and in the synthesis of two salts of the mesoionic compound with an influence on the effectiveness of norfloxacin, tetracycline, and erythromycin. There is a study on the antibacterial effects of some 5-nirtofuroyl derivatives but not on 5-nitrofuroyl chloride. There are no reports on its commercial use.

Uses

5-Nitro-2-furoyl Chloride is used as reactant in the synthesis of several therapeutic agents.

Environmental Fate

5-Nitrofuroyl chloride is a colorless crystal with molecular weight of 175.53 g mol^-1. It is stable under normal temperature and pressure on the basis of its melting point (38–14℃). There are no available data on its solubility in water. The bioaccumulation factor (BCF) for this compound is 4.29 at pH 7.4, which indicates low accumulation in aquatic organisms. The soil adsorption coefficient normalized to the content of organic carbon (Koc value) is 98.92 at pH 7.4, which indicates high mobility in soil.

5-NITRO-2-FUROYL CHLORIDE Preparation Products And Raw materials

Raw materials

Sodium hypochlorite 5-Nitrofurfural N,N-Dimethylformamide Sodium phosphate monobasic Benzene Hydrochloric acid Sodium bicarbonate Dichloromethane Dimethyl sulfoxide Thionyl chloride

Preparation Products

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5-NITRO-2-FUROYL CHLORIDE Suppliers

Belgium 1 China 20 Germany 2 Ukraine 1 United Kingdom 6 United States 10 Global 40

Meryer (Shanghai) Chemical Technology Co., Ltd.

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Sigma-Aldrich

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Shaanxi Dideu Medichem Co. Ltd

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Shanghai Aladdin Biochemical Technology Co.,Ltd.

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25084-14-4, 5-NITRO-2-FUROYL CHLORIDERelated Search:

5-Chloro-2-Nitroacetanilide 2-Furoyl chloride 5-NITRO-2-METHYLFURAN 2-NITROFURAN 5-Nitrofurfural 5-NITRO-2-FUROYL CHLORIDE 2-Chloromethylfuran 2-(chloromethyl)-5-nitro-furan (2-METHYL-PYRIDIN-3-YL)-METHANOL furoyl chloride

5-NITROFURAN-2-CARBONYL CHLORIDE

5-NITRO-2-FUROYL CHLORIDE

2-Furancarbonyl chloride, 5-nitro-

2-Furoyl chloride, 5-nitro-

5-nitrofuroyl chloride

Ai3-23633

Einecs 246-607-6

5-Nitro-2-furancarbonyl chloride

5-Nitro-2-furoyl chloride, predominantly trans, 97%

5-nitrofuran-2-carboxylic chloride

N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide

25084-14-4

C5H2ClNO4

ACID CHLORIDE

Building Blocks

C4 to C7

Chemical Synthesis

Furans

Heterocyclic Building Blocks