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5-NITRO-2-FUROYL CHLORIDE

Product Name
5-NITRO-2-FUROYL CHLORIDE
CAS No.
25084-14-4
Chemical Name
5-NITRO-2-FUROYL CHLORIDE
Synonyms
Ai3-23633;Einecs 246-607-6;5-nitrofuroyl chloride;5-NITRO-2-FUROYL CHLORIDE;2-Furoyl chloride, 5-nitro-;5-Nitro-2-furancarbonyl chloride;5-NITROFURAN-2-CARBONYL CHLORIDE;2-Furancarbonyl chloride, 5-nitro-;5-nitrofuran-2-carboxylic chloride;N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide
CBNumber
CB3470912
Molecular Formula
C5H2ClNO4
Formula Weight
175.53
MOL File
25084-14-4.mol
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5-NITRO-2-FUROYL CHLORIDE Property

Melting point:
34-41 °C
Boiling point:
137-140°C 15mm
Density 
1.588±0.06 g/cm3(Predicted)
Flash point:
137-140°C/15mm
Sensitive 
Moisture Sensitive
BRN 
139693
CAS DataBase Reference
25084-14-4(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
3261
WGK Germany 
3
Hazard Note 
Corrosive
HazardClass 
8
PackingGroup 
II
HS Code 
2932190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
683752
Product name
5-Nitro-2-furoyl chloride
Purity
95%
Packaging
5g
Price
$224
Updated
2024/03/01
Sigma-Aldrich
Product number
683752
Product name
5-Nitro-2-furoyl chloride
Purity
95%
Packaging
25g
Price
$908
Updated
2023/06/20
TRC
Product number
N493865
Product name
5-Nitro-2-furoyl chloride
Packaging
2.5g
Price
$240
Updated
2021/12/16
TRC
Product number
N493865
Product name
5-Nitro-2-furoyl chloride
Packaging
5g
Price
$330
Updated
2021/12/16
SynQuest Laboratories
Product number
4H54-5-Z8
Product name
5-Nitrofuran-2-carbonyl chloride
Packaging
5G
Price
$226
Updated
2021/12/16
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5-NITRO-2-FUROYL CHLORIDE Chemical Properties,Usage,Production

Description

5-Nitrofuroyl chloride is a furan chain bound to an acyl and a nitro group. Nitrofuran derivatives have been used as antibiotic and antimicrobial drugs but the acyl group bound to furan (furoyl chloride) is an intermediate for the synthesis of pharmaceuticals (e.g. antibiotics). 5-Nitrofuroyl chloride has been used as a reagent for the synthesis of some compounds with antibacterial properties and other chemicals.

Uses

5-Nitrofuroyl chloride has been used in the synthesis of certain ureides of furanmonocarboxylic acid and in the synthesis of two salts of the mesoionic compound with an influence on the effectiveness of norfloxacin, tetracycline, and erythromycin. There is a study on the antibacterial effects of some 5-nirtofuroyl derivatives but not on 5-nitrofuroyl chloride. There are no reports on its commercial use.

Uses

5-Nitro-2-furoyl Chloride is used as reactant in the synthesis of several therapeutic agents.

Environmental Fate

5-Nitrofuroyl chloride is a colorless crystal with molecular weight of 175.53 g mol-1. It is stable under normal temperature and pressure on the basis of its melting point (38–14℃). There are no available data on its solubility in water. The bioaccumulation factor (BCF) for this compound is 4.29 at pH 7.4, which indicates low accumulation in aquatic organisms. The soil adsorption coefficient normalized to the content of organic carbon (Koc value) is 98.92 at pH 7.4, which indicates high mobility in soil.

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25084-14-4, 5-NITRO-2-FUROYL CHLORIDERelated Search:


  • 5-NITROFURAN-2-CARBONYL CHLORIDE
  • 5-NITRO-2-FUROYL CHLORIDE
  • 2-Furancarbonyl chloride, 5-nitro-
  • 2-Furoyl chloride, 5-nitro-
  • 5-nitrofuroyl chloride
  • Ai3-23633
  • Einecs 246-607-6
  • 5-Nitro-2-furancarbonyl chloride
  • 5-Nitro-2-furoyl chloride, predominantly trans, 97%
  • 5-nitrofuran-2-carboxylic chloride
  • N-[bis(2-chloroethyl)aminomethyl]-4-methylbenzamide
  • 25084-14-4
  • C5H2ClNO4
  • ACID CHLORIDE
  • Building Blocks
  • C4 to C7
  • Chemical Synthesis
  • Furans
  • Heterocyclic Building Blocks