3,5-Difluoro-2-nitrophenol
- Product Name
- 3,5-Difluoro-2-nitrophenol
- CAS No.
- 151414-46-9
- Chemical Name
- 3,5-Difluoro-2-nitrophenol
- Synonyms
- 3,5-DIFLUORO-2-NITROPHENOL;Phenol, 3,5-difluoro-2-nitro-;2,4-Difluoro-6-hydroxynitrobenzene
- CBNumber
- CB3493939
- Molecular Formula
- C6H3F2NO3
- Formula Weight
- 175.09
- MOL File
- 151414-46-9.mol
3,5-Difluoro-2-nitrophenol Property
- Melting point:
- 46.1-46.5
- Boiling point:
- 241.6±35.0 °C(Predicted)
- Density
- 1.619±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- crystalline solid
- pka
- 2.60±0.20(Predicted)
- color
- Yellow
- InChI
- InChI=1S/C6H3F2NO3/c7-3-1-4(8)6(9(11)12)5(10)2-3/h1-2,10H
- InChIKey
- LIQHPNDCQUCZKL-UHFFFAOYSA-N
- SMILES
- C1(O)=CC(F)=CC(F)=C1[N+]([O-])=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P272Contaminated work clothing should not be allowed out of the workplace.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P391Collect spillage. Hazardous to the aquatic environment
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D447218
- Product name
- 3,5-Difluoro-2-nitrophenol
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- PC9743
- Product name
- 3,5-Difluoro-2-nitrophenol
- Purity
- 98%
- Packaging
- 1g
- Price
- $56
- Updated
- 2021/12/16
- Product number
- 4654-3-58
- Product name
- 3,5-Difluoro-2-nitrophenol
- Purity
- 99%
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
- Product number
- AMTH174
- Product name
- 3,5-Difluoro-2-nitrophenol
- Packaging
- 5g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- CS-0036890
- Product name
- 3,5-Difluoro-2-nitrophenol
- Purity
- 99.17%
- Packaging
- 5g
- Price
- $142
- Updated
- 2021/12/16
3,5-Difluoro-2-nitrophenol Chemical Properties,Usage,Production
Synthesis
315-14-0
62018-65-9
151414-46-9
(Step 1) Synthesis of 3,5-difluoro-2-nitrophenol: Dimethyl sulfoxide (DMSO, 50 mL) and 10 N sodium hydroxide solution (12 mL, 120 mmol) were added to a reaction flask, followed by 1,3,5-trifluoro-2-nitrobenzene (10.0 g, 56.5 mmol). The reaction mixture was stirred at room temperature for 15 hours. Upon completion of the reaction, water (100 mL) and ether (200 mL) were added for stratification. The aqueous layer was collected, acidified with 1 N hydrochloric acid and extracted with ether (2 x 200 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, and the solvent was removed by distillation under reduced pressure. The crude product was purified by silica gel column chromatography using chloroform-ethyl acetate (10:1, v/v) as eluent to afford the title compound 3,5-difluoro-2-nitrophenol (7.97 g, 81% yield) as a yellow crystalline powder.1H-NMR (CDCl3) δ: 6.53-6.59 (m, 1H), 6.66-6.70 (m, 1H), and 10.87 (d, J = 1.2 Hz, 1H).
References
[1] Patent: EP1346982, 2003, A1
3,5-Difluoro-2-nitrophenol Preparation Products And Raw materials
Raw materials
Preparation Products
3,5-Difluoro-2-nitrophenol Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88
View Lastest Price from 3,5-Difluoro-2-nitrophenol manufacturers
- Product
- 3,5-Difluoro-2-nitrophenol 151414-46-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 97.2%
- Supply Ability
- 100 tons
- Release date
- 2022-02-08
- Product
- 3,5-Difluoro-2-nitrophenol 151414-46-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-02