SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
- Product Name
- SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
- CAS No.
- 206986-87-0
- Chemical Name
- SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9
- Synonyms
- Sodium cholate hydrate;Sodium cholate[C6445];Sodium cholate[C1254];Cholic aicd sodiuM Salt;Cholalic acid sodium salt;SODIUM CHOLATE HYDRATE, 98 %;Sodium cholate hydrate, 99.5%;Cholic aicd sodium Salt hydrate;SODIUM CHOLATE HYDRATE, SIGMAULTRA;SODIUM CHOLATE HYDRATE, BIOCHEMIKA
- CBNumber
- CB3497588
- Molecular Formula
- C24H43NaO6
- Formula Weight
- 450.59
- MOL File
- 206986-87-0.mol
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Property
- RTECS
- FZ9600000
- storage temp.
- Store at RT.
- solubility
- H2O: 0.1 M, clear
- form
- Powder
- color
- White
- biological source
- bovine bile
ovine bile - optical activity
- [α]20/D +36±2°, c = 0.6% in ethanol (dry matter)
- Water Solubility
- Soluble in water.
- BRN
- 3582354
- InChIKey
- WPVYVBXDAUNXSZ-WQYDRJRFNA-N
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H303May be harmfulif swallowed
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 27029
- Product name
- Sodium cholate hydrate
- Purity
- ≥97.0% (dried material, NT)
- Packaging
- 100g
- Price
- $213
- Updated
- 2025/07/31
- Product number
- 27029
- Product name
- Sodium cholate hydrate
- Purity
- ≥97.0% (dried material, NT)
- Packaging
- 500g
- Price
- $855
- Updated
- 2025/07/31
- Product number
- S1702
- Product name
- Sodium cholate hydrate
- Purity
- PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production.
- Packaging
- 100g
- Price
- $408
- Updated
- 2025/07/31
- Product number
- S1702
- Product name
- Sodium cholate hydrate
- Purity
- PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production.
- Packaging
- 1kg
- Price
- $2077
- Updated
- 2025/07/31
- Product number
- C6445
- Product name
- Sodium cholate hydrate
- Purity
- BioXtra, ≥99%
- Packaging
- 10g
- Price
- $75.5
- Updated
- 2025/07/31
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Chemical Properties,Usage,Production
Uses
Biochemical solubilizing agent Sodium cholate hydrate is a non-denaturing detergent used for the extraction of membrane proteins. It is involved in the study to assess infiltration of pressurized promoter solutions in a mesoporous silica. Further, it serves as a biochemical solubilizing agent.
Uses
Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.
Uses
Non-denaturing detergent used for extraction of membrane proteins.
General Description
Sodium cholate hydrate is a non-denaturing, anionic detergent.
Biochem/physiol Actions
Reduction in 12-α hydroxylase activity leads to low levels of cholic acid in liver disease.
in vivo
Cholic acid (1% (w/w) Cholic acid-supplemented diet; p.o.; 14 days) decreases SHP (small heterodimer partner) protein expression, potentially via the upregulation of miR142-3p. Cholic acid increases CYP2D6 expression and activity[2].
| Animal Model: | Tg-CYP2D6 adult male mice (8 weeks of age and weighing 20–25 g)[2] |
| Dosage: | 1% (w/w) Cholic acid-supplemented diet |
| Administration: | Oral, 14 days |
| Result: | Decreases SHP expression and increased CYP2D6 activity. |
IC 50
Human Endogenous Metabolite
SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from SODIUM CHOLATE HYDRATE, BIOCHEMIKA, >= 9 manufacturers
- Product
- Sodium cholate hydrate 206986-87-0
- Price
- US $23.00-16.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 75000kg/month
- Release date
- 2023-03-08
- Product
- sodium cholate hydrate 206986-87-0
- Price
- US $100.00/bag
- Min. Order
- 1bag
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-09-05
- Product
- SODIUM CHOLATE HYDRATE, BIOCHEMIKA 206986-87-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-09