12-HYDROXYDODECANOIC ACID

Product Name: 12-HYDROXYDODECANOIC ACID
CAS No.: 505-95-3
Chemical Name: 12-HYDROXYDODECANOIC ACID
Synonyms: 12-HYDROXYLAURIC ACID;12-hydroxydodecanic acid;12-HYDROXYDODECANOIC ACID;Dodecanoic acid, 12-hydroxy-;12-Hydroxydodecanoic acid 97%;12-Hydroxydodecanoic acid - [H94813];12-Hydroxydodecanoic acid, 10 mM in DMSO;12-Hydroxydodecanoic acid, 97% white powder;2-[(5-Methylfuran-2-yl)methyl]-2,3-dihydro-1H-pyrazol-3-imine hydrochloride
CBNumber: CB7405020
Molecular Formula: C12H24O3
Formula Weight: 216.32
MOL File: 505-95-3.mol

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12-HYDROXYDODECANOIC ACID Property

Melting point:: 85-88 °C(lit.)
Boiling point:: 296.74°C (rough estimate)
Density: 0.988±0.06 g/cm3 (20 ºC 760 Torr)
refractive index: 1.4410 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 4.78±0.10(Predicted)
form: Solid
color: White
BRN: 1238370
Stability:: Stable. Incompatible with bases, reducing agents and oxidizing agents. Combustible. May cause dust explosion when mixed with air.
InChI: 1S/C12H24O3/c13-11-9-7-5-3-1-2-4-6-8-10-12(14)15/h13H,1-11H2,(H,14,15)
InChIKey: ZDHCZVWCTKTBRY-UHFFFAOYSA-N
SMILES: OCCCCCCCCCCCC(O)=O
LogP: 2.866 (est)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 198781
Product name: 12-Hydroxydodecanoic acid
Purity: 97%
Packaging: 1g
Price: $126
Updated: 2026/03/19

Sigma-Aldrich

Product number: 198781
Product name: 12-Hydroxydodecanoic acid
Purity: 97%
Packaging: 5g
Price: $328
Updated: 2026/03/19

TCI Chemical

Product number: H1092
Product name: 12-Hydroxydodecanoic Acid
Purity: min. 95.0 %
Packaging: 1G
Price: $70
Updated: 2026/03/19

TCI Chemical

Product number: H1092
Product name: 12-Hydroxydodecanoic Acid
Purity: min. 95.0 %
Packaging: 5G
Price: $210
Updated: 2026/03/19

Cayman Chemical

Product number: 28494
Product name: 12-hydroxy Lauric Acid
Packaging: 1g
Price: $44
Updated: 2024/03/01

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12-HYDROXYDODECANOIC ACID Chemical Properties,Usage,Production

Chemical Properties

white to off-white powder

Uses

12-Hydroxylauric Acid is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum.

Uses

12-Hydroxydodecanoic acid was used in the synthesis of high molecular weight poly[(12-hydroxydodecanoate)-co-(12-hydroxystearate)] [poly(12HD-co-12HS)] samples with variable monomer ratios using methyl 12-hydroxystearate.

Definition

ChEBI: 12-hydroxylauric acid is a medium-chain fatty acid that is the 12-hydroxylated derivative of lauric acid. It has a role as a human metabolite. It is functionally related to a dodecanoic acid. It is a conjugate acid of a 12-hydroxylaurate.

Synthesis

In the hydrothermal reactor, terminal chlorinated dodecanoic acid and NaOH solution were added, and the reaction was stopped after hydrothermal alkaline hydrolysis at the specified temperature for a specified time, and the crude product of terminal hydroxydodecanoic acid was obtained by filtration. The pure product of terminal hydroxydodecanoic acid used for structure and purity identification was obtained by acidifying the crude product of terminal chlorinated 12-acid, and then purified by recrystallization with petroleum ether (60-90 ), and the pure product of terminal hydroxydodecanoic acid used for application performance testing was obtained by neutralization of the above. The crude product was derivatized by methyl esterification with boron trifluoride - ether/methanol solution, extracted with anhydrous ether, and the upper ether layer was analyzed by GC for the content of each component (area normalization method), and the yield (Y) of terminal hydroxy12 acid was calculated.

IC 50

Human Endogenous Metabolite

Purification Methods

Crystallise the acid from toluene [Sadowik et al. J Am Chem Soc 108 7789 1986]. [Beilstein 3 III 658.]

12-HYDROXYDODECANOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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12-HYDROXYDODECANOIC ACID Suppliers

China 125 France 1 Germany 1 India 3 Switzerland 1 Ukraine 1 United Kingdom 2 United States 19 Global 153

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View Lastest Price from 12-HYDROXYDODECANOIC ACID manufacturers

Honest Joy Holdings Limited

Product: 12-hydroxydodecanoic acid 505-95-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 97.2%
Supply Ability: 100 tons
Release date: 2022-02-18

Zhuozhou Wenxi import and Export Co., Ltd

Product: 12-Hydroxydodecanoic acid 97% 505-95-3
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

Career Henan Chemical Co

Product: 12-HYDROXYDODECANOIC ACID 505-95-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

505-95-3, 12-HYDROXYDODECANOIC ACIDRelated Search:

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Dodecanoic acid, 12-hydroxy-

12-HYDROXYLAURIC ACID

12-HYDROXYDODECANOIC ACID

12-Hydroxydodecanoic acid, 97% white powder

12-Hydroxydodecanoic acid 97%

12-hydroxydodecanic acid

2-[(5-Methylfuran-2-yl)methyl]-2,3-dihydro-1H-pyrazol-3-imine hydrochloride

12-Hydroxydodecanoic acid, 10 mM in DMSO

12-Hydroxydodecanoic acid - [H94813]

505-95-3

HOCH211COOH

Organic Building Blocks

C11 to C12

Carbonyl Compounds

Carboxylic Acids

Building Blocks

CARBOXYLIC ACID