ChemicalBook > CAS DataBase List > 5-FLUOROOROTIC ACID HYDRATE 98

5-FLUOROOROTIC ACID HYDRATE 98

Product Name: 5-FLUOROOROTIC ACID HYDRATE 98
CAS No.: 220141-70-8
Chemical Name: 5-FLUOROOROTIC ACID HYDRATE 98
Synonyms: Fluoroorotic Monohydrate;5-FLUOROOROTIC ACID HYDRATE 98;5-FOA (5-Fluoroorotic acid), Monohydrate;5-Fluoroorotic Acid Monohydrate (Ultra Pure);5-fluoro-2,4-dioxo-1H-pyrimidine-6-carboxylic acid;5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyriMidine-4-carboxylic acid hydrate;5-Fluoroorotic Acid Monohydrate (5-FOA Monohydrate) for molecular biology, 98%
CBNumber: CB3499289
Molecular Formula: C5H5FN2O5
Formula Weight: 192.1020032
MOL File: 220141-70-8.mol

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5-FLUOROOROTIC ACID HYDRATE 98 Property

Melting point:: 278 °C (dec.)(lit.)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: Aqueous Base (Heated), DMSO (Sparingly, Heated), Methanol (Sparingly), Water (Sl
form: Solid
color: Must be White
Water Solubility: Soluble in water, dimethyl sulfoxide, 50mg in 1ml (1:1 ammonium hydroxide: water) with gentle heating.
Merck: 14,4176
BRN: 181933

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26-36
WGK Germany: 3
RTECS: UV7800000
HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: F0382
Product name: 5-Fluoroorotic Acid Monohydrate
Purity: >95.0%(HPLC)(T)
Packaging: 100mg
Price: $16
Updated: 2025/07/31

TCI Chemical

Product number: F0382
Product name: 5-Fluoroorotic Acid Monohydrate
Purity: >95.0%(HPLC)(T)
Packaging: 1g
Price: $49
Updated: 2025/07/31

Cayman Chemical

Product number: 17318
Product name: 5-fluoro Orotic Acid (hydrate)
Purity: ≥95%
Packaging: 500mg
Price: $61
Updated: 2024/03/01

Cayman Chemical

Product number: 17318
Product name: 5-fluoro Orotic Acid (hydrate)
Purity: ≥95%
Packaging: 1g
Price: $112
Updated: 2024/03/01

TRC

Product number: F595000
Product name: 5-FluorooroticAcidMonohydrate(UltraPure)
Packaging: 1g
Price: $90
Updated: 2021/12/16

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5-FLUOROOROTIC ACID HYDRATE 98 Chemical Properties,Usage,Production

Description

5-fluoro Orotic acid (5-FOA) is used to detect URA3 gene expression in yeast molecular genetic constructs. Yeast with an active URA3 gene, which encodes orotine-5''-monophosphate decarboxylase, converts 5-FOA to fluorodeoxyuridine, which is toxic to cells. Resistant strains of yeast that carry a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil.

Uses

5-Fluoroorotic Acid, Monohydrate (5-FOA) has become a valuable tool for research in the field of molecular genetics and has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5í-phosphate decarboxylation.

References

[1] F WINSTON. Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae.[J]. Genetics, 1984, 107 2: 179-197. DOI: 10.1093/genetics/107.2.179

5-FLUOROOROTIC ACID HYDRATE 98 Preparation Products And Raw materials

Raw materials

Preparation Products

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220141-70-8, 5-FLUOROOROTIC ACID HYDRATE 98Related Search:

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220141-70-8