ChemicalBook > CAS DataBase List > 5-FLUOROOROTIC ACID HYDRATE 98

5-FLUOROOROTIC ACID HYDRATE 98

Product Name
5-FLUOROOROTIC ACID HYDRATE 98
CAS No.
220141-70-8
Chemical Name
5-FLUOROOROTIC ACID HYDRATE 98
Synonyms
Fluoroorotic Monohydrate;5-FLUOROOROTIC ACID HYDRATE 98;5-FOA (5-Fluoroorotic acid), Monohydrate;5-Fluoroorotic Acid Monohydrate (Ultra Pure);5-fluoro-2,4-dioxo-1H-pyrimidine-6-carboxylic acid;5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyriMidine-4-carboxylic acid hydrate;5-Fluoroorotic Acid Monohydrate (5-FOA Monohydrate) for molecular biology, 98%
CBNumber
CB3499289
Molecular Formula
C5H5FN2O5
Formula Weight
192.1020032
MOL File
220141-70-8.mol
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5-FLUOROOROTIC ACID HYDRATE 98 Property

Melting point:
278 °C (dec.)(lit.)
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
Aqueous Base (Heated), DMSO (Sparingly, Heated), Methanol (Sparingly), Water (Sl
form 
Solid
color 
Must be White
Water Solubility 
Soluble in water, dimethyl sulfoxide, 50mg in 1ml (1:1 ammonium hydroxide: water) with gentle heating.
Merck 
14,4176
BRN 
181933
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Safety

Hazard Codes 
Xn
Risk Statements 
22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
UV7800000
HazardClass 
IRRITANT
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0382
Product name
5-Fluoroorotic Acid Monohydrate
Purity
>95.0%(HPLC)(T)
Packaging
100mg
Price
$16
Updated
2024/03/01
TCI Chemical
Product number
F0382
Product name
5-Fluoroorotic Acid Monohydrate
Purity
>95.0%(HPLC)(T)
Packaging
1g
Price
$49
Updated
2024/03/01
Alfa Aesar
Product number
B21290
Product name
5-Fluoroorotic acid monohydrate, 98%
Packaging
50mg
Price
$32.1
Updated
2021/12/16
Alfa Aesar
Product number
B21290
Product name
5-Fluoroorotic acid monohydrate, 98%
Packaging
1g
Price
$266
Updated
2021/12/16
Cayman Chemical
Product number
17318
Product name
5-fluoro Orotic Acid (hydrate)
Purity
≥95%
Packaging
500mg
Price
$61
Updated
2024/03/01
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5-FLUOROOROTIC ACID HYDRATE 98 Chemical Properties,Usage,Production

Description

5-fluoro Orotic acid (5-FOA) is used to detect URA3 gene expression in yeast molecular genetic constructs. Yeast with an active URA3 gene, which encodes orotine-5''-monophosphate decarboxylase, converts 5-FOA to fluorodeoxyuridine, which is toxic to cells. Resistant strains of yeast that carry a mutation in the URA3 gene grow in the presence of 5-FOA if the media is supplemented with uracil.

Uses

5-Fluoroorotic Acid, Monohydrate (5-FOA) has become a valuable tool for research in the field of molecular genetics and has been employed in the selection of resistant strains of Saccharomyces cerevisiae that possess a mutant URA3 gene which renders them orotidine-5í-phosphate decarboxylation.

5-FLUOROOROTIC ACID HYDRATE 98 Preparation Products And Raw materials

Raw materials

Preparation Products

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220141-70-8, 5-FLUOROOROTIC ACID HYDRATE 98Related Search:

Orotic acid 5-Fluoroorotic acid 5-FLUOROOROTIC ACID HYDRATE, 98

  • 5-FLUOROOROTIC ACID HYDRATE 98
  • 5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyriMidine-4-carboxylic acid hydrate
  • 5-FOA (5-Fluoroorotic acid), Monohydrate
  • Fluoroorotic Monohydrate
  • 5-Fluoroorotic Acid Monohydrate (Ultra Pure)
  • 5-Fluoroorotic Acid Monohydrate (5-FOA Monohydrate) for molecular biology, 98%
  • 5-fluoro-2,4-dioxo-1H-pyrimidine-6-carboxylic acid
  • 220141-70-8