2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98
Application Application- Product Name
- 2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98
- CAS No.
- 913835-94-6
- Chemical Name
- 2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98
- Synonyms
- ETHYL 4-BORONO-3-CHLOROBENZOATE;2-CHLORO-4-(ETHOXYCARBONYL)PHENYLBORONIC ACID;2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID;Benzoic acid, 4-borono-3-chloro-, 1-ethyl ester;2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98;2-Chloro-4-(ethoxycarbonyl)benzeneboronic acid 98%
- CBNumber
- CB3501038
- Molecular Formula
- C9H10BClO4
- Formula Weight
- 228.44
- MOL File
- 913835-94-6.mol
2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98 Property
- Melting point:
- 115-118
- storage temp.
- Sealed in dry,2-8°C
Safety
- Hazard Codes
- Xi
- Hazard Note
- Irritant/Keep Cold
- HS Code
- 2931900090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- E926203
- Product name
- Ethyl4-borono-3-chlorobenzoate
- Packaging
- 250mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- 093172
- Product name
- (2-Chloro-4-(ethoxycarbonyl)phenyl)boronic acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $152
- Updated
- 2021/12/16
- Product number
- X1454
- Product name
- 2-Chloro-4-(ethoxycarbonyl)phenylboronicacid
- Packaging
- 1g
- Price
- $177
- Updated
- 2021/12/16
- Product number
- 6660-5-10
- Product name
- 2-Chloro-4-(ethoxycarbonyl)benzeneboronic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $200
- Updated
- 2021/12/16
- Product number
- 093172
- Product name
- (2-Chloro-4-(ethoxycarbonyl)phenyl)boronic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $336
- Updated
- 2021/12/16
2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98 Chemical Properties,Usage,Production
Application
Ethyl 4-boron-3-chlorobenzoate can be used as a pharmaceutical synthesis intermediate in the Suzuki coupling reaction. CN107207488 reports that ethyl 4-boron-3-chlorobenzoate can be used to prepare 3-chloro-4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-thiadiazol-3-yl)benzoic acid, which selectively activates retinoic acid receptor β (RARβ) (e.g., RARβ2) in vitro or in vivo.
Application
Preparation of methyl 3-chloro-4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-thiadiazole-3-yl)benzoate: 0.323 mmol of 3-bromo-5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-thiadiazole, ethyl 4-boron-3-chlorobenzoate, 0.388 mmol of K3PO4·H2O, 0.647 mmol of Pd(Ph3P)4, 0.03 mmol of DMF (2 mL), and 0.5 mL of H2O were added to a sealed tube. The mixture was heated in a microwave reactor at 130 °C for 15 min. The mixture was cooled to RT and partitioned between DCM (10 mL) and H2O (3 mL). The organic solution was washed with water (3 mL), passed through a phase separation column, and concentrated under vacuum. The residue was purified by silica gel chromatography in isohexane (0-10% EtOAc) to give methyl 3-chloro-4-(5-(4,7-dimethylbenzofuran-2-yl)-1,2,4-thiadiazol-3-yl)benzoate.
2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98 Preparation Products And Raw materials
Raw materials
Preparation Products
2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98 Suppliers
- Tel
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- Fax
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- sales@apolloscientific.co.uk
- Country
- United Kingdom
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View Lastest Price from 2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98 manufacturers
- Product
- 2-CHLORO-4-(ETHOXYCARBONYL)BENZENEBORONIC ACID 98 913835-94-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-100%
- Supply Ability
- 1
- Release date
- 2018-08-12