TRAM-34

Product Name: TRAM-34
CAS No.: 289905-88-0
Chemical Name: TRAM-34
Synonyms: RAM-34;CS-1574;TRAM34;TRAM 34;Triarylmethane-34;TRAM-34 USP/EP/BP;Clotrimazole Impurity 8;Des Imidazole 1-pyrazole;Clotrimazole TRAM-34 Impurity;TRAM34;TRAM 34;TRIARYLMETHANE-34;1-[(2-Chlorophenyl)diphenylmethyl]-
CBNumber: CB3505056
Molecular Formula: C22H17ClN2
Formula Weight: 344.84
MOL File: 289905-88-0.mol

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TRAM-34 Property

Melting point:: 145-147°C
storage temp.: 2-8°C
solubility: DMSO: ~11 mg/mL
form: solid
color: off-white
Water Solubility: Soluble in DMSO at 2mg/ml. Insoluble in water
CAS DataBase Reference: 289905-88-0

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T6700
Product name: TRAM 34
Purity: ≥98% (HPLC), solid
Packaging: 5mg
Price: $194
Updated: 2024/03/01

Sigma-Aldrich

Product number: T6700
Product name: TRAM 34
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $610
Updated: 2024/03/01

Alfa Aesar

Product number: J60019
Product name: TRAM 34
Packaging: 25mg
Price: $286
Updated: 2023/06/20

Cayman Chemical

Product number: 23385
Product name: TRAM 34
Purity: ≥98%
Packaging: 5mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 23385
Product name: TRAM 34
Purity: ≥98%
Packaging: 10mg
Price: $68
Updated: 2024/03/01

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TRAM-34 Chemical Properties,Usage,Production

Chemical Properties

Yellow Solid

Definition

ChEBI: TRAM-34 is an organochlorine compound.

Biological Activity

Highly selective blocker of intermediate conductance Ca 2+ -activated K + channels (IK Ca 1, K Ca 3.1) (K d = 20 nM). Exhibits 200-1500-fold selectivity over K V , BK Ca , SK Ca , Na + , CRAC and Cl - channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.

Biochem/physiol Actions

TRAM-34 exhibits 100-fold selectivity (Kd = 20 nM) for IKCa1 channels over other K+ channels (Charybdotoxin, Kd = 5 nM, Clotrimazole, Kd = 70 nM; Nitrendipine Kd = 900 nM). Furthermore, TRAM-34 is known to suppress the activation of human T lymphocytes,.

storage

+4°C

TRAM-34 Preparation Products And Raw materials

Raw materials

Preparation Products

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TRAM-34 Suppliers

Canada 1 China 101 France 1 India 2 Switzerland 1 United Kingdom 2 United States 22 Global 130

SIGMA-RBI

Tel: --
Fax: --
Country: Switzerland
ProdList: 6896
Advantage: 91

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View Lastest Price from TRAM-34 manufacturers

Career Henan Chemical Co

Product: TRAM-34 289905-88-0
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-01-30

289905-88-0, TRAM-34Related Search:

Glibenclamide CHARYBDOTOXIN ETHYLTRITYLETHER ClotriMazole IMpurity A 1-Chloro-2-(dichlorophenylMethyl)benzene Ivabradine hydrochloride Amiodarone hydrochloride Lenalidomide Belinostat (PXD101) Chlorpromazine hydrochloride Nicorandil 5-HYDROXYDECANOIC ACID SODIUM SALT CLOFILIUM TOSYLATE Gabapentin-lactam PAXILLINE N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE 1-Tritylpyrazole TRAM-34

CS-1574

TRAM34;TRAM 34

1-[(2-chlorophenyl)-diphenylmethyl]pyrazole

Clotrimazole TRAM-34 Impurity

Triarylmethane-34

Clotrimazole Impurity 8

TRAM34;TRAM 34;TRIARYLMETHANE-34

1-[(2-Chlorophenyl)diphenylmethyl]-

1H-Pyrazole, 1-[(2-chlorophenyl)diphenylmethyl]-

TRAM-34 USP/EP/BP

4-chloro-2,3-dihydro-1H-indene-6-carboxylicacid

Carbonochloridicacid,9-methylphenylester

RAM-34

TRAM34,Inhibitor,Potassium Channel,KcsA,inhibit,TRAM-34

Des Imidazole 1-pyrazole

289905-88-0

Heterocyclic Compounds

Heterocycles

Inhibitors