ChemicalBook > CAS DataBase List > OXIDIZED NIFEDIPINE
OXIDIZED NIFEDIPINE
- Product Name
- OXIDIZED NIFEDIPINE
- CAS No.
- 67035-22-7
- Chemical Name
- OXIDIZED NIFEDIPINE
- Synonyms
- B 4759;BAY-b-4759;Nifedipine-1;Dehydro Nifedipine;NIFEDIPINE EP IMP A;Nifidipine Impurity A;Nitrophenyl nifedipine;Nifedipine impurity A CRS;Nifedipine impurity A (EP);Divalproex Sodium Impurity 1
- CBNumber
- CB3505238
- Molecular Formula
- C17H16N2O6
- Formula Weight
- 344.32
- MOL File
- 67035-22-7.mol
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OXIDIZED NIFEDIPINE Property
- Melting point:
- 100-105 °C
- Boiling point:
- 443.7±45.0 °C(Predicted)
- Density
- 1.284±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- powder
- pka
- 1.55±0.29(Predicted)
- color
- yellow
- EPA Substance Registry System
- 3,5-Pyridinedicarboxylic acid, 2,6-dimethyl-4-(2-nitrophenyl)-,3,5-dimethyl ester (67035-22-7)
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- UC167
- Product name
- Oxidized Nifedipine
- Purity
- powder, ~95% (HPLC)
- Packaging
- 5mg
- Price
- $469
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 1463600
- Product name
- Nifedipine Nitrophenylpyridine Analog
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 25mg
- Price
- $1530
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23229
- Product name
- Dehydro Nifedipine
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23229
- Product name
- Dehydro Nifedipine
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $193
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- UC167
- Product name
- Oxidized Nifedipine
- Purity
- powder, ~95% (HPLC)
- Packaging
- 10mg
- Price
- $861
- Updated
- 2024/03/01
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OXIDIZED NIFEDIPINE Chemical Properties,Usage,Production
Description
Dehydro nifedipine is an active metabolite of nifedipine , a calcium channel blocker present in formulations used to treat hypertension and angina. Dehydro nifedipine is formed when nifedipine is metabolized by the cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM.
Chemical Properties
Pale Yellow Solid
Uses
Oxidized nifedipine has been used for apoptotic signaling studies in dopaminergic neurons.
Uses
The main Nifedipine metabolite in human plasma
Definition
ChEBI: Dehydronifedipine is a phenylpyridine.
Biochem/physiol Actions
CYP3A4 nifedipine metabolite. Nifedipine (parent compound) is an antianginal and antihypertensive agent.
OXIDIZED NIFEDIPINE Preparation Products And Raw materials
Raw materials
Preparation Products
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OXIDIZED NIFEDIPINE Suppliers
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- 010-82848833 400-666-7788
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- China
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- United States
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- orderCN@merckgroup.com
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View Lastest Price from OXIDIZED NIFEDIPINE manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- Oxidized Nifedipine 67035-22-7
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2019-12-27
67035-22-7, OXIDIZED NIFEDIPINERelated Search:
Nifedipine
METHYL 2-(O-NITROBENZYLIDENE)-ACETOACETATE
Methyl 3-aminocrotonate
2,6-Ntp
Dehydro Nifedipine N-Oxide
diethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Nifedipine Impurity J
Hydroxydehydro Nifedipine Carboxylate
methyl 2,4-bis{2-nitrophenyl}-6-methyl-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
Nifedipine Impurity 9
2,6-DIMETHYL-4-(3-NITRO-PHENYL)-PYRIDINE-3,5-DICARBOXYLIC ACID DIMETHYL ESTER
Nifendipine Impurity G
nifedipine iMpurity C
Hydroxy Dehydro Nifedipine Lactone
3-aminocrotonamide
Nifedipine impurity 10
Nifedipine EP IMpurity-B
Nifedipine EP IMpurity-C