ChemicalBook > CAS DataBase List > 2 6-DICHLORO-4-NITROPYRIDINE 97

2 6-DICHLORO-4-NITROPYRIDINE 97

Product Name
2 6-DICHLORO-4-NITROPYRIDINE 97
CAS No.
25194-01-8
Chemical Name
2 6-DICHLORO-4-NITROPYRIDINE 97
Synonyms
2,6-Dichloro-4-nitropyridine;benzylsulfonylmethylbenzene;Pyridine,2,6-dichloro-4-nitro-;2 6-DICHLORO-4-NITROPYRIDINE 97;2,6-Dichloro-4-nitropyridine 97%;phenylmethylsulfonylmethylbenzene;25194-01-8;2 6-DICHLORO-4-NITROPYRIDINE 97 ISO 9001：2015 REACH
CBNumber
CB3505399
Molecular Formula
C5H2Cl2N2O2
Formula Weight
192.99
MOL File
25194-01-8.mol
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2 6-DICHLORO-4-NITROPYRIDINE 97 Property

Melting point:
94-98 °C
Boiling point:
282.9±35.0 °C(Predicted)
Density 
1.629±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Gold to faint brown/tan, tiny crystalline flakes
pka
-5.10±0.10(Predicted)
Appearance
Off-white to light yellow Solid
InChI
InChI=1S/C5H2Cl2N2O2/c6-4-1-3(9(10)11)2-5(7)8-4/h1-2H
InChIKey
BZYQSSVTQJTUDD-UHFFFAOYSA-N
SMILES
C1(Cl)=NC(Cl)=CC([N+]([O-])=O)=C1
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-37/38-41-43-36/37/38
Safety Statements 
26-39-36/37/39
WGK Germany 
3
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
647411
Product name
2,6-Dichloro-4-nitropyridine
Purity
97%
Packaging
5g
Price
$115
Updated
2023/06/20
Sigma-Aldrich
Product number
647411
Product name
2,6-Dichloro-4-nitropyridine
Purity
97%
Packaging
1g
Price
$41.7
Updated
2023/01/07
Usbiological
Product number
D3531-45
Product name
2,6-Dichloro-4-nitropyridine
Packaging
500mg
Price
$425
Updated
2021/12/16
TRC
Product number
D435625
Product name
2,6-Dichloro-4-nitropyridine
Packaging
10g
Price
$1100
Updated
2021/12/16
AK Scientific
Product number
W4843
Product name
2,6-Dichloro-4-nitropyridine
Packaging
1g
Price
$14
Updated
2021/12/16
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2 6-DICHLORO-4-NITROPYRIDINE 97 Chemical Properties,Usage,Production

Uses

2,6-Dichloro-4-nitropyridine (cas# 25194-01-8) is a compound useful in organic synthesis.

Synthesis Reference(s)

Synthetic Communications, 18, p. 659, 1988 DOI: 10.1080/00397918808077351

Synthesis

2587-00-0

25194-01-8

The general procedure for the synthesis of 2,6-dichloro-4-nitropyridine from 2,6-dichloropyridine-N-oxide was as follows: 2,6-dichloropyridine-N-oxide (12.8 g, 78 mmol) was added to a mixed solution consisting of 95% concentrated nitric acid (21 mL) and 98% concentrated sulfuric acid (50 mL). The reaction was stirred at 148 °C for 1 h. The temperature was subsequently raised to 156 °C until no more nitrogen dioxide gas was released. After completion of the reaction, the reaction solution was cooled to room temperature and slowly poured into 150 g of ice water. The pH of the mixture was adjusted to 6 with ammonia, at which point a solid product precipitated. The solid was collected by filtration and the resulting crude product was recrystallized with petroleum ether to give 10 g of yellow solid product in 66.4% yield.

References

[1] Patent: US2012/289497, 2012, A1. Location in patent: Page/Page column 51-52
[2] Patent: EP2524917, 2012, A1. Location in patent: Page/Page column 58-59
[3] Organic Letters, 2004, vol. 6, # 5, p. 659 - 662
[4] Nucleosides, Nucleotides and Nucleic Acids, 2003, vol. 22, # 12, p. 2133 - 2144

2 6-DICHLORO-4-NITROPYRIDINE 97 Preparation Products And Raw materials

Raw materials

Preparation Products

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2 6-DICHLORO-4-NITROPYRIDINE 97 Suppliers

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View Lastest Price from 2 6-DICHLORO-4-NITROPYRIDINE 97 manufacturers

R&D Scientific Inc.
Product
2,6-Dichloro-4-nitropyridine 25194-01-8
Price
US $1600.00/Kg
Min. Order
0.100Kg
Purity
98
Supply Ability
5000 Kg
Release date
2025-01-22
Dideu Industries Group Limited
Product
2 6-DICHLORO-4-NITROPYRIDINE 25194-01-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-08
Career Henan Chemical Co
Product
2 6-DICHLORO-4-NITROPYRIDINE 97 25194-01-8
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
Customized
Release date
2019-07-02

25194-01-8, 2 6-DICHLORO-4-NITROPYRIDINE 97Related Search:

2,4-Dichloro-3-nitropyridine 2,3-DICHLORO-5-NITROPYRIDINE 2,6-Dichloro-3-nitropyridine 3,5-DICHLORO-4-NITROPYRIDINE 2,5-Dichloro-3-nitropyridine 2,4-DICHLORO-5-NITROPYRIDINE 2,6-DICHLORO-4-NITROPYRIDINE-N-OXIDE (3alpha)-3-chloro-Cholest-4-ene 2,6-DICHLORO-3-NITRO-4-AMINOPYRIDINE

  • 2 6-DICHLORO-4-NITROPYRIDINE 97
  • 2,6-Dichloro-4-nitropyridine
  • benzylsulfonylmethylbenzene
  • phenylmethylsulfonylmethylbenzene
  • 2,6-Dichloro-4-nitropyridine 97%
  • Pyridine,2,6-dichloro-4-nitro-
  • 2 6-DICHLORO-4-NITROPYRIDINE 97 ISO 9001：2015 REACH
  • <font color="#ff0000">25194-01-8</font>
  • 25194-01-8
  • 95194-01-8
  • C5 to C6
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Heterocycle-Pyridine series
  • Building Blocks
  • C5
  • Aromatics
  • Miscellaneous Reagents
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines