6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID
- Product Name
- 6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID
- CAS No.
- 5463-29-6
- Chemical Name
- 6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID
- Synonyms
- 6-bromo-2-oxo-1H-quinoline-4-carboxylic acid;6-bromo-2-keto-1H-quinoline-4-carboxylic acid;6-Bromo-2-oxo-1,2-dihydroquinoline-5-carboxylic acid;4-Quinolinecarboxylic acid, 6-bromo-1,2-dihydro-2-oxo-
- CBNumber
- CB3507010
- Molecular Formula
- C10H6BrNO3
- Formula Weight
- 268.06
- MOL File
- 5463-29-6.mol
6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Property
- Boiling point:
- 446.7±45.0 °C(Predicted)
- Density
- 1.804±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 2.54±0.20(Predicted)
- Appearance
- Off-white to light yellow Solid
Safety
- HazardClass
- IRRITANT
- HS Code
- 2933491090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- R423203
- Product name
- 6-BROMO-2-HYDROXY-QUINOLINE-4-CARBOXYLIC ACID
- Purity
- Aldrich<sup>CPR</sup>
- Packaging
- 1 unit
- Price
- $113
- Updated
- 2025/07/31
- Product number
- R423203
- Product name
- 6-BROMO-2-HYDROXY-QUINOLINE-4-CARBOXYLIC ACID
- Purity
- AldrichCPR
- Packaging
- 50MG
- Price
- $110
- Updated
- 2024/03/01
- Product number
- 010461
- Product name
- 6-Bromo-2-hydroxyquinoline-4-carboxylic acid
- Packaging
- 1g
- Price
- $378
- Updated
- 2021/12/16
- Product number
- 115070
- Product name
- 6-Bromo-2-oxo-1,2-dihydroquinoline-4-carboxylic acid
- Purity
- >97%
- Packaging
- 500mg
- Price
- $451
- Updated
- 2021/12/16
- Product number
- OR310688
- Product name
- 6-Bromo-2-oxo-1,2-dihydroquinoline-4-carboxylicacid
- Packaging
- 1g
- Price
- $520
- Updated
- 2021/12/16
6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
541-50-4
87-48-9
5463-29-6
6-Bromo-2-hydroxy-4-carboxylic acid quinoline was synthesized using the method described in Scheme 6. The procedure was as follows: 5-bromoindoline-2,3-dione (0.250 g) was dissolved in tetrahydrofuran (THF, 3 ml) in a round-bottomed flask, followed by the addition of malonic acid (2 equiv). The unit was connected to a reflux condenser and heated to reflux by conventional heating and the reaction was continued overnight. After 12 hours of reaction, a solid precipitate was observed to be generated. Subsequently, the suspension was concentrated under reduced pressure to remove the solvent, and the suspension was refluxed for 4 hours after addition of an appropriate amount of water. Finally, the solid product was collected by filtration to afford 6-bromo-2-hydroxyquinoline-4-carboxylic acid (0.150 g) in solid form.
References
[1] Patent: US2014/221387, 2014, A1. Location in patent: Paragraph 0383; 0384; 0385
6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
6-BROMO-2-HYDROXYQUINOLINE-4-CARBOXYLIC ACID Suppliers
- Tel
- --
- Fax
- --
- sales@apolloscientific.co.uk
- Country
- United Kingdom
- ProdList
- 6084
- Advantage
- 88