2-CHLORO-6-NITROANISOLE

Product Name: 2-CHLORO-6-NITROANISOLE
CAS No.: 80866-77-9
Chemical Name: 2-CHLORO-6-NITROANISOLE
Synonyms: ST012276;Einecs 279-580-4;Anisole, 2-chloro-6-nitro-;3-Chloro-2-methoxynitrobenzene;l-chloro-2-methoxy-3-nitrobenzene;3-Chloro-2-methoxy-1-nitrobenzene;3-Chloro-2-methoxynitrobenzene98%;3-Chloro-2-methoxynitrobenzene 98%;Benzene, 1-chloro-2-methoxy-3-nitro-
CBNumber: CB3511596
Molecular Formula: C7H6ClNO3
Formula Weight: 187.58
MOL File: 80866-77-9.mol

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2-CHLORO-6-NITROANISOLE Property

storage temp.: Sealed in dry,Room Temperature
form: solid
color: beige

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39
HS Code: 2921490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S461369
Product name: 2-CHLORO-6-NITROANISOLE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $30.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: S461369
Product name: 2-CHLORO-6-NITROANISOLE
Purity: Aldrich
Packaging: 250mg
Price: $29.8
Updated: 2024/03/01

TRC

Product number: C596888
Product name: 2-Chloro-6-nitroanisole
Packaging: 25mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C596888
Product name: 2-Chloro-6-nitroanisole
Packaging: 50mg
Price: $60
Updated: 2021/12/16

TRC

Product number: C596888
Product name: 2-Chloro-6-nitroanisole
Packaging: 250mg
Price: $75
Updated: 2021/12/16

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2-CHLORO-6-NITROANISOLE Chemical Properties,Usage,Production

Synthesis

3209-22-1

124-41-4

80866-77-9

General procedure: 2,3-dichloronitrobenzene 488g (2.51mol), methanol 1928g, diisopropylamine 25g (0.25mol) were added to a four-necked flask, heated to 60°C, 28% sodium methanol solution 396.4g (0.5mol) was added slowly dropwise, and the etherification reaction was carried out at a maintained temperature for 5h. Samples were taken to monitor the reaction process. After the reaction was completed, the solvent was removed by distillation under reduced pressure, 200g of water was added, the slurry was formed by stirring, the solids were washed, the solids were collected by filtration, the filter cake was washed with water, and dried in vacuum to obtain 141.46g of 2-chloro-6-nitroanisole, with an etherification reaction yield of 85% and a purity of 95%. 39.9g 2-chloro-6-nitroanisole was added into 500mL autoclave, 0.4g 1% platinum-carbon catalyst and 120g methanol were added, the temperature was raised to 40℃, the pressure was adjusted to 0.4MPa, the reaction was carried out for 18h, and samples were taken to monitor the process. At the end of the reaction, the catalyst was removed by filtration, methanol was removed by distillation under reduced pressure, and 32g of 3-chloroanisidine was precipitated, with 96% yield, >93% purity, and 81.6% total yield.

References

[1] Patent: CN103787846, 2016, B. Location in patent: Paragraph 0042; 0043
[2] Recueil des Travaux Chimiques des Pays-Bas, 1916, vol. 35, p. 17,25

2-CHLORO-6-NITROANISOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-6-NITROANISOLE Suppliers

China 66 India 1 Switzerland 1 United Kingdom 5 United States 9 Global 82

Shandong RuiYue Biotechnology Co., Ltd.

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Energy Chemical

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Tianjin Anhao Biological Technology Co., Ltd.

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80866-77-9, 2-CHLORO-6-NITROANISOLERelated Search:

5-CHLORO-2-NITROANISOLE 2,6-DICHLORO-4-NITROANISOLE 4-Chloro-3-nitroanisole 1-Bromo-2-chloro-4-methoxy-5-nitrobenzene 2-Chloro-4-nitoranisole 2-CHLORO-5-NITROANISOLE 4-Chloro-2-nitroanisole 2-CHLORO-6-NITROANISOLE 4-(2-CHLORO-6-NITROPHENOXY)BENZENE-1-SULFONYL CHLORIDE 2,4-DICHLORO-6-NITROANISOLE 4-[(2,4-DICHLORO-6-NITROPHENOXY)METHYL]-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-5-YL 2,4-DICHLOROPHENYL ETHER 3,6-Dichloro-2,4-dinitrophenyl methacrylate METHYL 3-(2-CHLORO-6-NITROPHENOXY)-2-THIOPHENECARBOXYLATE Crotonic acid, 3,6-dichloro-2,4-dinitrophenyl ester 3,4,6-Trichloro-2-nitrophenyl-3,4-dichlorocarbanilate AKOS B030719 AKOS B030847 AKOS B030848

3-Chloro-2-methoxynitrobenzene 98%

3-Chloro-2-methoxynitrobenzene98%

3-Chloro-2-methoxynitrobenzene

3-Chloro-2-methoxy-1-nitrobenzene

Einecs 279-580-4

Anisole, 2-chloro-6-nitro-

Benzene, 1-chloro-2-methoxy-3-nitro-

ST012276

l-chloro-2-methoxy-3-nitrobenzene

80866-77-9

blocks

NitroCompounds

Miscellaneous