POLYPHYLLIN D

Product Name: POLYPHYLLIN D
CAS No.: 50773-41-6
Chemical Name: POLYPHYLLIN D
Synonyms: Paris I;Saponin Pa;Polyphyllin;Polyphyllin C;Polyphyllin I;POLYPHYLLIN D;Polyphyllin A;Polyphillin D;Polyphyllin Ⅰ;GLYCO-DIOSGENIN
CBNumber: CB3511798
Molecular Formula: C44H70O16
Formula Weight: 855.02
MOL File: 50773-41-6.mol

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POLYPHYLLIN D Property

Melting point:: >245°C (dec.)
Density: 1.40
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated), Pyridine (Slightly)
pka: 12?+-.0.70(Predicted)
form: Solid
color: White

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Safety

HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29179
Product name: Polyphyllin I
Packaging: 5mg
Price: $121
Updated: 2024/03/01

Cayman Chemical

Product number: 29179
Product name: Polyphyllin I
Packaging: 50mg
Price: $722
Updated: 2024/03/01

Cayman Chemical

Product number: 29179
Product name: Polyphyllin I
Packaging: 10mg
Price: $183
Updated: 2024/03/01

Cayman Chemical

Product number: 29179
Product name: Polyphyllin I
Packaging: 25mg
Price: $423
Updated: 2024/03/01

TRC

Product number: P689455
Product name: PolyphyllinI
Packaging: 10mg
Price: $150
Updated: 2021/12/16

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POLYPHYLLIN D Chemical Properties,Usage,Production

Description

Polyphyllin I is a steroid saponin that has been found in P. polyphylla and has anticancer activity. It decreases proliferation of, and induces apoptosis in, MCF-7 and MDA-MB-231 cells (IC₅₀s = 5 and 2.5 μM, respectively). It disrupts the mitochondrial membrane potential, activates caspase-3, and increases protein levels of the caspase-3 substrate poly(ADP-ribose) polymerase (PARP) in HepG2 and drug-resistant R-HepG2 cells. Polyphyllin I (2.05 and 2.73 mg/kg for 10 days) reduces tumor growth in an MCF-7 mouse xenograft model.

Uses

Polyphylin II is a natural saponin extracted from the plant, Paris polyphylla, and displays antiproliferative activity in vivo. Used in the treatment of lung and cervical cancers.

POLYPHYLLIN D Preparation Products And Raw materials

Raw materials

Preparation Products

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POLYPHYLLIN D Suppliers

China 162 Germany 2 United Kingdom 1 United States 16 Global 181

Carbosynth

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6005
Advantage: 58

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View Lastest Price from POLYPHYLLIN D manufacturers

Sinoway Industrial co., ltd.

Product: Chondroitin Saponin 50773-41-6
Price: US $0.00-0.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 0.98
Supply Ability: 20 tons
Release date: 2024-06-27

Shaanxi Haibo Biotechnology Co., Ltd

Product: POLYPHYLLIN D 50773-41-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-08-22

Shanghai Standard Technology Co., Ltd.

Product: Polyphyllin I 50773-41-6
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-28

50773-41-6, POLYPHYLLIN DRelated Search:

(25R)-3β-(2-O-α-L-Rhamnopyranosyl-β-D-glucopyranosyloxy)spirosta-5-ene Nystatin Mesaconitine PolyphyllinH Spiro[8H-naphth[2',1':4,5]indeno[2,1-b]furan-8,2'-[2H]pyran] alpha-D-glucopyranoside deriv. ANTI-GALECTIN-7 POLYPHYLLIN E (RG) (3beta,25R)-14-Hydroxyspirost-5-en-3-yl O-6-deoxy-alpha-L-mannopyranosyl-(1-2)-O-[beta-D-xylopyranosyl-(1-4)]-beta-D-glucopyranoside poricoic acid A 3-methyl ester Resibufogenin formosanin C Pennogenin3-O-α-L-rhamnopyranosyl-(1→2)-[α-L-rhamnopyranosyl-(1→4)]-β-D-glucopyranoside Chonglou Saponin VII 22,25-Epoxy-2,3,14,20-tetrahydroxycholest-7-en-6-one beta-Sitosterol Bufotaline ALLEOSIDE A Bufa-20,22-dienolide, 3,5,14-trihydroxy-19-oxo-, (3beta,5beta)-

POLYPHYLLIN D

Polyphyllin

Polyphyllin I

Polyphyllin C

Paris saponin Pa

Polyphillin D

Polyphyllin A

Paridis saponin I

Paris I

Saponin Pa

Chonglou Saponin I(Polyphyllin A)

Polyphyllin Ⅰ

I,Chonglousaponin

Polyphyllin I(Chonglou Saponin I)

Polyphyllin D / Diosgenyl 4-O-α-L-arabinofuranosyl-2-O-α-L-rhamnopyranosyl-β -D-glucopyranoside

Polyphyllin I, 98%, from Paris polyphylla Smith var.chinensis

GLYCO-DIOSGENIN

β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→2)]-

POLYPHYLLIN D USP/EP/BP

Chondroitin Saponin

(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-(((2S,3R,4R,5S)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4-hydroxy-6-(hydroxymethyl)-2-(((4S,5'R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-5',6a,8a,9-tetramethyl-1,3,3',4,4',5,5',6,6a,6b,6',7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol

50773-41-6

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract