LUCIFERASE
Description Source Background- Product Name
- LUCIFERASE
- CAS No.
- 61970-00-1
- Chemical Name
- LUCIFERASE
- Synonyms
- RFLuc;Ultra-Glo;LUCIFERASE;EC 1.14.14.3;EC 1.13.12.7;Luciferase from;Einecs 263-359-4;Beetle luciferase;LUCIFERASE FIREFLY;FIREFLY LUCIFERASE
- CBNumber
- CB3663963
- Formula Weight
- 0
- MOL File
- Mol file
LUCIFERASE Property
- Flash point:
- 111℃
- storage temp.
- -20°C
- form
- powder
- color
- white
- Specific Activity
- 15-30×106light units/mg protein
Safety
- Hazard Codes
- Xi,Xn,T
- Risk Statements
- 36/37/38-22-52/53-45
- Safety Statements
- 26-36/37-24/25-23-22-61-45-53
- WGK Germany
- 3
- F
- 3-10-21
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P314Get medical advice/attention if you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- L9420
- Product name
- Luciferase from Photinus pyralis (firefly)
- Purity
- recombinant, expressed in E. coli, buffered aqueous solution, ≥10×1010 units/mg protein
- Packaging
- 1mg
- Price
- $136
- Updated
- 2025/07/31
- Product number
- L9420
- Product name
- Luciferase from Photinus pyralis (firefly)
- Purity
- recombinant, expressed in E. coli, buffered aqueous solution, ≥10×1010 units/mg protein
- Packaging
- 5x1mg
- Price
- $547
- Updated
- 2025/07/31
- Product number
- 20398
- Product name
- Luciferase (firefly recombinant)
- Purity
- ≥95% estimated by SDS-PAGE
- Packaging
- 1mL
- Price
- $130
- Updated
- 2024/03/01
- Product number
- SRE0045
- Product name
- Luciferase from
- Purity
- recombinant, expressed in E. coli, lyophilized powder, ≥1×1011 units/mg protein
- Packaging
- 1mg
- Price
- $132
- Updated
- 2025/07/31
- Product number
- SRE0045
- Product name
- Luciferase from
- Purity
- recombinant, expressed in E. coli, lyophilized powder, ≥1×1011 units/mg protein
- Packaging
- 2mg
- Price
- $248
- Updated
- 2025/07/31
LUCIFERASE Chemical Properties,Usage,Production
Description
Luciferase (firefly recombinant) is a light-generating enzyme that catalyzes an oxidative reaction, using luciferin, ATP, and molecular oxygen to produce oxyluciferin, which yields visible light. The bioluminescence of this ATP-dependent luciferase is commonly used in reporter systems that are amenable to high-throughput screening.
Uses
Firefly luciferase is used extensively in molecular and cell biology, in particular for the efficient detection and quantitation of ATP and as a reporter for genetic function.
Uses
Luciferase from Photinus pyralis (firefly) has been used as a component of lysis solution to measure luminescence signals, as part of the study to determine chemical signals which can activate the karrikin insensitive 2 (KAI2) pathway.
General Description
Firefly luciferase catalyzes the reaction of luciferin with ATP and leads to the production of yellow-green light. The enzyme has a molecular weight of 62kDa and is expressed in peroxisomes. Luciferase is considered as a model to study protein–anesthetic interactions. Firefly luciferase is highly useful in cell biology and molecular biology, as a reporter of gene function and for the quantification of ATP.
Biochem/physiol Actions
Firefly luciferase is a 62 kDa protein that catalyzes the production of light. The enzyme requires ATP, molecular oxygen, and the heterocyclic compound, firefly luciferin, to generate light in a two-step process. The light producing reaction is initiated by luciferin activation (adenylation of its carboxylate group) and proceeds in the presence of molecular oxygen to yield a photon of yellow-green light.
Description
Luciferase produced in E.Coli is a single, non-glycosylated polypeptide chain containing 571 amino acids (1-550 a.a.) and having a molecular mass of 62.9kDa.
Luciferase is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Source
Escherichia Coli
Background
Luciferase is a general term for the class of oxidative enzymes used in bioluminescence and is distinct from a photoprotein. Luciferase catalyzes a bioluminescent reaction which involves the substrate luciferin as well as Mg2+ and ATP, produces green light with a wavelength of 562 nm. Luciferase from firefly is broadly used as a reporter for studying gene regulation and function, and for pharmaceutical screening.
References
[1] BALDWIN T O. Firefly luciferase: the structure is known, but the mystery remains.[J]. Structure, 1996, 4 3: 223-228. DOI: 10.1016/s0969-2126(96)00026-3
[2] TINGTING XU. The Expanding Toolbox of In Vivo Bioluminescent Imaging.[J]. Frontiers in Oncology, 2016: 150. DOI: 10.3389/fonc.2016.00150
[3] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
LUCIFERASE Preparation Products And Raw materials
Raw materials
Preparation Products
LUCIFERASE Suppliers
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View Lastest Price from LUCIFERASE manufacturers
- Product
- N-Benzoylglycyl-3-methylphenylalanine 61970-00-1
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- as request
- Release date
- 2018-12-25