3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER

Product Name: 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
CAS No.: 119205-38-8
Chemical Name: 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
Synonyms: Methyl 3-aMino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate;methyl 3-amino-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylate;Ethyl 3-amino-3a,4,5,6,7,7a-hexahydrobenzo[b]thiophene-2-carboxylate;3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER;Benzo[b]thiophene-2-carboxylic acid, 3-amino-4,5,6,7-tetrahydro-, methyl ester;3-Amino-4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid methyl ester ,97%
CBNumber: CB3670288
Molecular Formula: C10H13NO2S
Formula Weight: 211.28
MOL File: 119205-38-8.mol

More

Less

3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Property

Melting point:: 70-73 °C
Boiling point:: 414.3±45.0 °C(Predicted)
Density: 1.273±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 2.24±0.20(Predicted)
Appearance: White to off-white Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 3282AA
Product name: Methyl3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate
Packaging: 100mg
Price: $185
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0007076
Product name: 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
Purity: 98.00%
Packaging: 250MG
Price: $376.95
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: AAA0007076
Product name: 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER
Purity: 98.00%
Packaging: 5G
Price: $1848
Updated: 2021/12/16

Ambeed

Product number: A237026
Product name: Methyl3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate
Purity: 97%
Packaging: 100mg
Price: $107
Updated: 2021/12/16

Ambeed

Product number: A237026
Product name: Methyl3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate
Purity: 97%
Packaging: 250mg
Price: $160
Updated: 2021/12/16

More

Less

3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

1263199-68-3

119205-38-8

Ethyl methyl-S-(2-cyanocyclohex-1-enyl)sulfonate (9) (0.17 g, 0.78 mmol) was used as the starting material and it was mixed with freshly distilled anhydrous THF (3 mL). Potassium tert-butoxide (0.09 g, 0.78 mmol) was subsequently added and the reaction mixture was heated to reflux for 30 min. The reaction progress was monitored by thin layer chromatography (TLC) (eluent: petroleum ether/ethyl acetate, 5:1). After completion of the reaction, the mixture was concentrated under reduced pressure, dissolved by addition of dichloromethane (25 mL) and washed with distilled water (2 x 20 mL), and the organic phase was dried over anhydrous magnesium sulfate. After evaporation of the solvent, the resulting oil was dried under high vacuum (10^-1 mbar). After refrigeration overnight, the light yellow solid product methyl 3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate (135 mg, 80% yield) was obtained. The product was characterized as follows: melting point 70-73 °C; 1H NMR (CDCl3) δ: 1.82 (m, 4H, H5, H6), 2.30 (m, 2H, H7), 2.67 (m, 2H, H4), 3.79 (s, 3H, COOCH3), 5.36 (br s, 2H, NH2); 13C NMR (CDCl3) δ. 21.9, 22.6 (2CH2, C5, C6), 23.1 (CH2, C4), 25.8 (CH2, C7), 51.1 (COOCH3), 97.3 (CAr), 126.2 (CAr), 143.5 (CAr), 152.6 (CAr), 165.4 (COOCH3); IR (KBr) ν: 768 , 1072, 1095, 1130, 1198, 1263, 1300, 1342, 1448, 1493, 1568, 1604, 1668, 1734 (ester), 2858, 2933, 3361 (NH2), 3464 (NH2) cm^-1 ; MS (EI, 70 eV) m/z (%): 32 ( 80), 40 (10), 45 (10), 65 (10), 77 (15), 91 (15), 118 (15), 151 (65), 179 (90), 211 (M+, 100), 212 (M+H+, 10); HRMS-FAB: m/z [M+H]+ calcd for C10H13NO2S. 211.0667; found: 211.0745.

References

[1] Tetrahedron Letters, 2011, vol. 52, # 3, p. 401 - 403

3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Methyl thioglycolate Acetic anhydride N,N-Dimethylformamide Phosphorus oxitrichloride Trichloroethylene Cyclohexanone

Preparation Products

More

Less

3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER Suppliers

China 26 India 1 United Kingdom 2 United States 4 Global 33

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

ShangHai Angti Biotechnology Co., Ltd.

Tel: 13764913901
Fax: -
Email: info@angtibio.com
Country: China
ProdList: 4985
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 15083
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Zhuzhou focus pharmaceutical technology co., LTD

Tel: +86-13776644403
Email: robert@focuspharma.cc
Country: China
ProdList: 2459
Advantage: 58

Hunan Jibang Biological Technology Co., LTD

Tel: +8613776644403
Email: sales02@kingboomtech.com
Country: China
ProdList: 1804
Advantage: 58

Ningbo Zeyu Chemical Technology Co., Ltd

Tel: 15066123231
Email: 2278736577@qq.com
Country: China
ProdList: 492
Advantage: 58

Shandong chuangyingchemical Co., Ltd.

Tel: 18853181302
Email: sale@chuangyingchem.com
Country: CHINA
ProdList: 5906
Advantage: 58

Jiangsu Hongmin Pharmaceutical Co., Ltd.

Tel: 18221292452
Email: fannieliu@glschina.com
Country: China
ProdList: 6798
Advantage: 58

Shanghai Kaiwei Chemical Technology Co., Ltd.

Tel: 021-58461859 15821823057
Email: service@aiviche.com
Country: China
ProdList: 49312
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9947
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44894
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39665
Advantage: 58

Jiaxing Deyi Chemical Co., Ltd

Tel: 0573-85866609 13588473046
Email: 824930988@qq.com
Country: China
ProdList: 7865
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Shanghai Hansi Chemical Industry Co., Ltd.

Tel: 17717618050
Email: zllg@gh-reagent.com
Country: China
ProdList: 10420
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Guangzhou WeiBo Chemical Co., Ltd.

Tel: --
Fax: --
Email: weibochem@163.com
Country: China
ProdList: 6187
Advantage: 67

119205-38-8, 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTERRelated Search:

4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID ETHYL ESTER AURORA 21044 AURORA 20730 3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER AURORA 21207 AURORA 20425 METHYL 3-AMINO-6-TERT-BUTYL-4,5,6,7-TETRAHYDRO-1-BENZOTHIOPHENE-2-CARBOXYLATE

3-AMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID METHYL ESTER

methyl 3-amino-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylate

Methyl 3-aMino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate

Ethyl 3-amino-3a,4,5,6,7,7a-hexahydrobenzo[b]thiophene-2-carboxylate

3-Amino-4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid methyl ester ,97%

Benzo[b]thiophene-2-carboxylic acid, 3-amino-4,5,6,7-tetrahydro-, methyl ester

119205-38-8