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1-Methyl-3-nitrophthalate

Product Name
1-Methyl-3-nitrophthalate
CAS No.
21606-04-2
Chemical Name
1-Methyl-3-nitrophthalate
Synonyms
)-6-nitrobenzoic Acid;Apremilast Impurity 85;1-Methyl-3-nitrophthalate;Sitagliptin Impurity 1-d4;METHYL2-CARBOXY-3-NITROBENZOATE;3-nitro-2-Carboxyl methyl benzoate;Methyl 3-nitro-2-carboxyl benzoate;2-methoxycarbonyl-6-nitrobenzoicaci;3-Nitro-phthalic acid 1-Methyl ester;2-Methoxyxcarbonyl-6-nitrobenzoic acid
CBNumber
CB3671043
Molecular Formula
C9H7NO6
Formula Weight
225.15
MOL File
21606-04-2.mol
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1-Methyl-3-nitrophthalate Property

Melting point:
160.0 to 164.0 °C
Boiling point:
409.2±35.0 °C(Predicted)
Density 
1.484±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
soluble in Acetone, Dichloromethane, Ethyl Acetate, Methanol
form 
Solid:particulate/powder
pka
1.87±0.30(Predicted)
color 
White to Almost white
CAS DataBase Reference
21606-04-2(CAS DataBase Reference)
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Safety

HS Code 
2917.39.7000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
S313416
Product name
3-NITRO-PHTHALIC ACID 1-METHYL ESTER
Purity
AldrichCPR
Packaging
25MG
Price
$29.8
Updated
2024/03/01
Sigma-Aldrich
Product number
S758086
Product name
1-METHYL 3-NITROPHTHALATE
Purity
AldrichCPR
Packaging
50MG
Price
$28.6
Updated
2023/06/20
TCI Chemical
Product number
M2795
Product name
2-(Methoxycarbonyl)-6-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$80
Updated
2024/03/01
TCI Chemical
Product number
M2795
Product name
2-(Methoxycarbonyl)-6-nitrobenzoic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$239
Updated
2024/03/01
TRC
Product number
M323773
Product name
Methyl3-Nitrophthalate
Packaging
10mg
Price
$100
Updated
2021/12/16
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1-Methyl-3-nitrophthalate Chemical Properties,Usage,Production

Chemical Properties

light yellow crystalline powder

Uses

Methyl 3-Nitrophthalate is an intermediate in the synthesis of (αS)-3-Ethoxy-4-methoxy-α-[(methylsulfonyl)methyl]-N-[(1S)-1-phenylethyl]-benzenemethanamine which is an impurity of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis.

1-Methyl-3-nitrophthalate Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Methyl-3-nitrophthalate Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9513
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19179
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
Advantage
52
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
9387
Advantage
52
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5653
Advantage
65
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
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View Lastest Price from 1-Methyl-3-nitrophthalate manufacturers

Career Henan Chemical Co
Product
1-Methyl-3-nitrophthalate 21606-04-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1kg-1000kg
Release date
2020-01-03

21606-04-2, 1-Methyl-3-nitrophthalateRelated Search:


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  • Methyl 3-nitro-2-carboxyl benzoate
  • 3-Nitro-phthalic acid 1-Methyl ester
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  • Apremilast Impurity 85
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  • 2-methoxycarbonyl-6-nitrobenzoicaci
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  • 21606-04-2