CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID

Product Name: CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
CAS No.: 1461-94-5
Chemical Name: CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID
Synonyms: RARECHEM AQ C4 0001;cis-1,2-Cyclobutanedicarboxylic acid;CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID;(1R,2S)-Cyclobutane-1,2-dicarboxylicaci;(1R,2S)-1,2-Cyclobutanedicarboxylic acid;(1R,2S)-Cyclobutane-1,2-dicarboxylic acid;[1R,2S,(-)]-1,2-Cyclobutanedicarboxylic acid;cis-Cyclobutane-1,2-dicarboxylic acid;(1R,2S)-rel-cyclobutane-1,2-dicarboxylic acid;1,2-Cyclobutanedicarboxylic acid, (1R,2S)-rel-
CBNumber: CB3683893
Molecular Formula: C6H8O4
Formula Weight: 144.13
MOL File: 1461-94-5.mol

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CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Property

Melting point:: 133-139 °C
Boiling point:: 377.7±35.0 °C(Predicted)
Density: 1.509±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
form: solid
pka: pK1:3.90 ;pK2:5.89 (25°C)
Appearance: White to off-white Solid
BRN: 2047669
InChI: InChI=1/C6H8O4/c7-5(8)3-1-2-4(3)6(9)10/h3-4H,1-2H2,(H,7,8)(H,9,10)/t3-,4+
InChIKey: SUSAGCZZQKACKE-ZXZARUISSA-N
SMILES: [C@@H]1(C(O)=O)CC[C@@H]1C(O)=O |&1:0,6,r|

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Safety

Hazard Codes: C,Xi
Risk Statements: 34-36/37/38
Safety Statements: 26-36/37/39-45-36
RIDADR: UN 3261 8/PG 3
WGK Germany: 3
HS Code: 2917200090
Storage Class: 8A - Combustible corrosive hazardous materials
Hazard Classifications: Skin Corr. 1B

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 28682
Product name: cis-Cyclobutane-1,2-dicarboxylic acid
Purity: ≥97.0% (T)
Packaging: 1g
Price: $258
Updated: 2025/07/31

Sigma-Aldrich

Product number: 28682
Product name: cis-Cyclobutane-1,2-dicarboxylic acid
Purity: ≥97.0% (T)
Packaging: 5g
Price: $815
Updated: 2025/07/31

Matrix Scientific

Product number: 082876
Product name: (1R,2S)-Cyclobutane-1,2-dicarboxylic acid
Purity: 97%
Packaging: 5g
Price: $987
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC76208
Product name: 1,2-Cyclobutanedicarboxylic Acid
Packaging: 5G
Price: $1400
Updated: 2021/12/16

Matrix Scientific

Product number: 082876
Product name: (1R,2S)-Cyclobutane-1,2-dicarboxylic acid
Purity: 97%
Packaging: 10g
Price: $1500
Updated: 2021/12/16

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CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

The interaction of the carboxyl groups in the fragmentation of the molecular ions of cis-cyclobutane-1,2-dicarboxylic acid helps to distinguish it from trans-cyclobutane-1,2-dicarboxylic acid.

General Description

The interaction of the carboxyl groups in the fragmentation of the molecular ions of cis-cyclobutane-1,2-dicarboxylic acid helps to distinguish it from trans-cyclobutane-1,2-dicarboxylic acid.

Purification Methods

Purify the acid by crystallisation from H2O or ligroin, or by hydrolysis of the anhydride [b 120-150o/40mm, m 77-77.5o (from *C6H6, 74-75o from H2O or ligroin)] with H2O. The diphenacyl ester has m 113o (from EtOH) and the p-bromodiphenacyl ester has m 153o (from EtOH/Me2CO). [Vogel Justus Liebigs Ann Chem 615 13 1958, Reed J Chem Soc 685 1951, Fison et al. J Am Chem Soc 56 1774 1934, pK: Bode Chem Ber 67 332 1934, Beilstein 9 IV 2788.]

CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID Suppliers

China 87 Germany 4 India 1 Switzerland 1 United Kingdom 6 United States 8 Global 107

Amoy Winchem Biotechnology Co. Ltd.

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Email: amoiyh@126.com
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Energy Chemical

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Shanghai Hanhong Scientific Co.,Ltd.

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Email: info@hanhongsci.com
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Nanjing Kaitian Chemical Co., Ltd.

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Hunan Hui Bai Shi Biotechnology Co., Ltd.

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Bide Pharmatech Ltd.

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ShangHai D&B Biological Science and Technology Co.Ltd

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Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 023-13650506873 19923294409
Email: xingcanyaoye@sina.com
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ProdList: 1604
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View Lastest Price from CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID 1461-94-5
Price: US $2.20-8.80/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-06-17

Longyan Tianhua Biological Technology Co., Ltd

Product: CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID 1461-94-5
Price: US $9.00/Kg/Bag
Min. Order: 25Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-11-13

Career Henan Chemical Co

Product: CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID 1461-94-5
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20kg
Release date: 2018-12-14

1461-94-5, CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACIDRelated Search:

1,2,3,4-Cyclobutanetetracarboxylic Dianhydride cis-Cyclobutane-1,3-dicarboxylic acid 1,2,3,4-CYCLOBUTANETETRACARBOXYLIC ACID Cyclobutanemethanol Adipic acid (R)-(+)-Methylsuccinic acid CIS-1,2-CYCLOBUTANEDICARBOXYLIC ACID DIMETHYL ESTER CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID 2,3-DIMETHYLSUCCINIC ACID MESO-2,3-DIMETHYLSUCCINIC ACID Cyclobutanecarboxaldehyde 2-METHYL CYCLOBUTANECARBOXYLIC ACID 2-Methylsuccinic acid Cyclobutanecarboxylic acid

RARECHEM AQ C4 0001

CIS-CYCLOBUTANE-1,2-DICARBOXYLIC ACID

(1R,2S)-Cyclobutane-1,2-dicarboxylic acid

(1R,2S)-1,2-Cyclobutanedicarboxylic acid

[1R,2S,(-)]-1,2-Cyclobutanedicarboxylic acid

cis-1,2-Cyclobutanedicarboxylic acid

(1R,2S)-rel-cyclobutane-1,2-dicarboxylic acid

cis-Cyclobutane-1,2-dicarboxylic acid

1,2-Cyclobutanedicarboxylic acid, (1R,2S)-rel-

(1R,2S)-Cyclobutane-1,2-dicarboxylicaci

cis-Cyclobutane-1,2-dicarboxylic acid

1461-94-5

Carbonyl Compounds

Carboxylic Acids

Building Blocks

Organic Building Blocks

C6

Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts

Carboxylic Acids

Ring Systems

Carbonyl Compounds

C6