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4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER

Product Name
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
CAS No.
65874-27-3
Chemical Name
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
Synonyms
tert-butyl 4-forMylbenzoate;4-(tert-Butoxycarbonyl)benzaldehyde;4-Formylbenzoic Acid tert-Butyl Ester;4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER;Benzoic acid, 4-formyl-, 1,1-dimethylethyl ester;4-ForMyl-benzoic acid Mono tert-butyl ester(70%)
CBNumber
CB3684128
Molecular Formula
C12H14O3
Formula Weight
206.24
MOL File
65874-27-3.mol
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4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Property

Melting point:
52.0 to 56.0 °C
Boiling point:
310.7±25.0 °C(Predicted)
Density 
1.093±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
color 
White to Orange to Green
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5414
Product name
tert-Butyl 4-Formylbenzoate
Purity
>98.0%(GC)
Packaging
1g
Price
$199
Updated
2025/07/31
TCI Chemical
Product number
B5414
Product name
tert-Butyl 4-Formylbenzoate
Purity
>98.0%(GC)
Packaging
5g
Price
$492
Updated
2025/07/31
TRC
Product number
B745425
Product name
tert-Butyl 4-Formylbenzoate
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
102870
Product name
4-Formyl-benzoic acid mono tert-butyl ester
Purity
>95%
Packaging
500mg
Price
$544
Updated
2021/12/16
ChemScene
Product number
CS-W007267
Product name
tert-Butyl 4-Formylbenzoate
Purity
>98.0%
Packaging
10g
Price
$299
Updated
2021/12/16
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4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Chemical Properties,Usage,Production

Synthesis

24424-99-5

619-66-9

65874-27-3

Example 1 Synthesis of tert-butyl 4-formylbenzoate: To a 250 mL round bottom flask were sequentially added tert-butyl para-formylbenzoate (5.0 g, 33 mmol), di-tert-butyl dicarbonate (14.54 g, 66.6 mmol), 4-dimethylaminopyridine (0.814 g, 6.66 mmol) and tetrahydrofuran (100 mL). The reaction mixture was stirred at room temperature for 16 hours. After completion of the reaction, the solvent was removed by distillation under reduced pressure to give the crude product. Ethyl acetate (150 mL) was added to the residue and washed with saturated sodium bicarbonate solution (25 mL) and water (25 mL). After partitioning, the aqueous phase was back-extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, washed with saturated saline (50 mL), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure. Finally, it was purified by fast column chromatography (eluent: petroleum ether to 10% ethyl acetate-petroleum ether gradient elution) to give tert-butyl 4-formylbenzoate (1.90 g, 28% yield) as a white solid. The product was characterized by 1H NMR (CDCl3, 400 MHz): δ 10.10 (s, 1H), 8.14 (d, J = 8.3 Hz, 2H), 7.93 (d, J = 8.5 Hz, 2H), 1.61 (s, 9H).

References

[1] Journal of the American Chemical Society,
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 7488 - 7489
[3] Patent: US2003/176495, 2003, A1
[4] Patent: US2011/212969, 2011, A1. Location in patent: Page/Page column 109

4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER Suppliers

Americas 1 China 67 Europe 1 India 4 Japan 1 United Kingdom 2 United States 9 Global 85
Accela ChemBio Inc.
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View Lastest Price from 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER manufacturers

Career Henan Chemical Co
Product
4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER 65874-27-3
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-14

65874-27-3, 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTERRelated Search:

tert-Butyl 4-ethynylbenzylcarbamate TERT-BUTYL 4-METHYL-3-OXOPENTANOATE TERT-BUTYL-4-CHLORO-3-OXOBUTANOATE TERT-BUTYL 4-ETHYNYLBENZOATE BETA-OXO-4-(TRIFLUOROMETHYL)-BENZENEPROPANOIC ACID 1,1-DIMETHYLETHYL ESTER TERT-BUTYL 4-METHOXY-3-OXOBUTANOATE T-BUTYL 4-FLUOROBENZOATE (4-IODO-BENZYL)-CARBAMIC ACID TERT-BUTYL ESTER TERT-BUTYL 4-IODOBUTYLCARBAMATE tert-Butyl 4-iodobenzoate 2,2-Dimethoxy-2-phenylacetophenone 4-Methyl-benzoic acid tert-butyl ester 4-(TERT-BUTOXYCARBONYL)BENZOIC ACID 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER 4-HYDROXY-4'-(TRIMETHYLACETOXY)BENZOPHENONE

  • 4-FORMYL-BENZOIC ACID MONO TERT-BUTYL ESTER
  • tert-butyl 4-forMylbenzoate
  • 4-ForMyl-benzoic acid Mono tert-butyl ester(70%)
  • Benzoic acid, 4-formyl-, 1,1-dimethylethyl ester
  • 4-(tert-Butoxycarbonyl)benzaldehyde
  • 4-Formylbenzoic Acid tert-Butyl Ester
  • 65874-27-3