Thidiazuron Property

Melting point:

213°C

Density 

1.3493 (rough estimate)

refractive index 

1.6390 (estimate)

storage temp. 

Sealed in dry,2-8°C

solubility 

Soluble in DMSO

pka

12.06±0.70(Predicted)

form 

Solid

color 

Light yellow to yellow

Merck 

13,9384

BRN 

1078092

InChIKey

HFCYZXMHUIHAQI-UHFFFAOYSA-N

CAS DataBase Reference

51707-55-2(CAS DataBase Reference)

EPA Substance Registry System

Thidiazuron (51707-55-2)

Safety

Hazard Codes 

Xi,N

Risk Statements 

36/37/38-51/53

Safety Statements 

22-26-36-61

RIDADR 

UN 3077 9 / PGIII

WGK Germany 

3

RTECS 

YU1395000

HS Code 

2934999090

Hazardous Substances Data

51707-55-2(Hazardous Substances Data)

Toxicity

LC50 (96-hour) for bluegill sun?sh, channel cat?sh and rainbow trout >1,000 mg/L (Hartley and Kidd, 1987); acute oral LD50 for rats >5,000 mg/kg (Hartley and Kidd, 1987), 5,350 mg/kg (RTECS, 1985).

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Thidiazuron Chemical Properties,Usage,Production

Chemical Properties

The pure product is a white odorless and tasteless crystalline solid. m.p.210～212.5°C (decomposition at 217°C), vapor pressure 4×10-9Pa) (25°C). Solubility at 25°C: dimethyl sulfoxide>500g/L, dimethylformamide>500g/L, cyclohexanone 21.5g/L, acetone 8g/L, methanol 4.5g/L, ethyl acetate 0.8 g/L, hexane 6mg/L, insoluble in aliphatic and aromatic hydrocarbons, solubility in water 31mg/L. The partition coefficient is 59 (pH=7.3). Stable below 200°C; stable to water at room temperature, half-life > 24d; half-life in soil < 60d.

Uses

Thidiazuron is a non-purine containing urea derivative with cytokinin activity. Thidiazuron is used as a cotton defoliant and a plant growth regulator in tissue culture.

Uses

Plant growth regulator used to defoliate cotton to facilitate harvesting.

Definition

ChEBI: Thidiazuron is a member of ureas.

General Description

Thidiazuron is a systemic herbicide, widely employed as an effective plant growth regulator and pre-harvest defoliant for crops such as cotton.

Agricultural Uses

Thidiazuron is substituted urea that is used to defoliate cotton plants. Thidiazuron, which has cytokinin activity, is one of the many harvesting aids needed in agriculture.

Agricultural Uses

Herbicide, Defoliant, Plant growth regulator: Used primarily as a cotton defoliant in order to increase the harvest yield. Not applied to food crops. Not approved for use in EU countries. Registered for use in the U.S. U.S. Maximum Allowable Residue Levels for Thidiazuron and its aniline-containing metabolites in or on the following food commodities: [40 CFR 180.403(a)]: cattle, fat 0.4 ppm; cattle, meat 0.4 ppm; cattle, meat byproducts 0.4 ppm; cotton, gin byproducts 24.0 ppm; cotton, undelinted seed 0.3 ppm; goat, fat 0.4 ppm; goat meat 0.4 ppm; goat, meat byproducts 0.4 ppm; hog, fat 0.4 ppm; hog, meat 0.4 ppm; hog, meat byproducts 0.4 ppm; horse, fat 0.4 ppm; horse, meat 0.4 ppm; horse, meat byproducts 0.4 ppm; milk 0.05 ppm; sheep, fat 0.4 ppm; sheep, meat 0.4 ppm; sheep, meat byproducts 0.4 ppm.

Trade name

DAZE®; DEFOLIT®; DROPP®; GINSTAR EC® (thidiazuron + diuron); LEAFLESS® Tthidiazuron; SN 49537®

Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx and NOx.

Environmental Fate

Soil. The reported half-life in soil is approximately 26–144 days (Hartley and Kidd, 1987).
Photolytic. Rapidly converted to the photoisomer, 1-phenyl-3-(1,2,5-thiadiazol-3- yl)urea (Worthing and Hance, 1991). When thidiazuron adsorbed by soil was exposed to UV light (λ <290 nm), 1-phenyl-3-(1,2,5-thiadiazol-3-yl)urea formed as the majo