Antihypertensives Uses
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Metroprolol succinate

Antihypertensives Uses
Product Name
Metroprolol succinate
CAS No.
98418-47-4
Chemical Name
Metroprolol succinate
Synonyms
Selozok;Toprol XL;rolol succinate;METOPROLOL SUCCINATE;metroprolol succinate;Maetaprolol succinate;Metoprolol succinate Base;Metoprolol Succinate (200 mg);Metoprolol Succinate (ToprolX);Metoprolol Succinate (1441298)
CBNumber
CB3686041
Molecular Formula
2C15H25NO3.C4H6O4
Formula Weight
652.82
MOL File
98418-47-4.mol
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Metroprolol succinate Property

Melting point:
136-138°C
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
Freely soluble in water, soluble in methanol, slightly soluble in ethanol (96 per cent), very slightly soluble in ethyl acetate.
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
RGHAZVBIOOEVQX-UHFFFAOYSA-N
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Safety

HS Code 
2922190900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H370Causes damage to organs

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2511
Product name
Metoprolol succinate
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
500MG
Price
$334
Updated
2024/03/01
Sigma-Aldrich
Product number
1441298
Product name
Metoprolol succinate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$857
Updated
2024/03/01
Cayman Chemical
Product number
15429
Product name
Metoprolol (succinate)
Packaging
25mg
Price
$117
Updated
2024/03/01
Cayman Chemical
Product number
15429
Product name
Metoprolol (succinate)
Packaging
250mg
Price
$807
Updated
2024/03/01
Cayman Chemical
Product number
15429
Product name
Metoprolol (succinate)
Packaging
50mg
Price
$222
Updated
2024/03/01
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Metroprolol succinate Chemical Properties,Usage,Production

Antihypertensives

At present, it is a selective β1 receptor blocker which is widely used for high blood pressure, coronary heart disease, chronic heart failure and cardiac arrhythmia treatment,Metroprolol succinate is a conventional tablet of metoprolol , its elimination half-life is shorter than others, about 3 to 4 hours, so the plasma drug concentration fluctuation is great, and2 to 4 times daily medication is necessary. To overcome these disadvantages, AstraZeneca's recently introduced metoprolol succinate sustained-release tablet is a new depot metoprolol , once-daily medication can guarantee 24 hours of constant metoprolol plasma concentration and β1-receptor blocking effect .On clinical pharmacology and therapeutics ,it has many advantages. Clinically it is used for the treatment of hypertension, angina pectoris, chronic heart failure with left ventricular systolic dysfunction and stable symptoms.
Oral, once a day, take preferably in the morning, it can be broken apart and taken, but you can not chew or crush,at least half a cup of liquid should be taken for delivery . At the same time food intake does not affect their bioavailability. Dosage should be individualized to avoid bradycardia. The following is an effective medication guide: high blood pressure: 47.5~95mg, once daily. Taking 95mg of metoprolol succinate sustained-release tablets may be ineffective in patients ,combine them with other anti-hypertensive drugs, preferably diuretics and dihydropyridine calcium antagonists, or increase the dose. Angina: 95~190mg, once daily.Combine them with nitrates or increase the dose if it is needed.
The above information is edited by the chemicalbook of Tian Ye.

Uses

High blood pressure medication.

Chemical Properties

White or almost white, crystalline powder.

Uses

Metoprolol Succinate is used in the treatment of patients suffering from chronic heart failure, as well as to treat blood pressure from mild hypertension. β-adrenoceptor antagonist or β-blocker.

Uses

Anti - hypertensives

Definition

ChEBI: Metoprolol succinate is an alcohol and a member of phenols.

brand name

Toprol (AstraZeneca).

Metroprolol succinate Preparation Products And Raw materials

Raw materials

Preparation Products

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Metroprolol succinate Suppliers

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Pharmaffiliates Analytics and Synthetics P. Ltd
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Ranbaxy Laboratories Limited
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UNICHEM LABORATORIES LTD
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View Lastest Price from Metroprolol succinate manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Metroprolol succinate 98418-47-4
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
1kg/month
Release date
2021-09-18
Hebei Mojin Biotechnology Co., Ltd
Product
Metroprolol succinate 98418-47-4
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2024-10-30
Hebei Yanxi Chemical Co., Ltd.
Product
Metroprolol succinate 98418-47-4
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-09-13

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