L-4-BENZOYLPHENYLALANINE

Product Name: L-4-BENZOYLPHENYLALANINE
CAS No.: 104504-45-2
Chemical Name: L-4-BENZOYLPHENYLALANINE
Synonyms: (S)-2-aMino-3-(4-benzoylphenyl)propanoic acid;H-BPA-OH;4-BENZOYL-L-PHENYLALANINE;P-BENZOYL-L-PHENYLALANINE;(2S)-2-aMino-3-(4-benzoylphenyl)propanoic acid;Al660-1;L-Bpa-OH;H-4-Bz-Phe-Oh;H-P-BZ-PHE-OH;H-PHE(P-BZ)-OH
CBNumber: CB3686238
Molecular Formula: C16H15NO3
Formula Weight: 269.3
MOL File: 104504-45-2.mol

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L-4-BENZOYLPHENYLALANINE Property

Boiling point:: 467.6±40.0 °C(Predicted)
Density: 1.249±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
solubility: DMF: insol; DMSO: insol; Ethanol: insol; PBS (pH 7.2): insol
form: A solid
pka: 2.16±0.10(Predicted)
color: White to light yellow
InChI: InChI=1S/C16H15NO3/c17-14(16(19)20)10-11-6-8-13(9-7-11)15(18)12-4-2-1-3-5-12/h1-9,14H,10,17H2,(H,19,20)/t14-/m0/s1
InChIKey: TVIDEEHSOPHZBR-AWEZNQCLSA-N
SMILES: C(O)(=O)[C@H](CC1=CC=C(C(=O)C2=CC=CC=C2)C=C1)N

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Safety

Safety Statements: 24/25
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific

Product number: O027
Product name: L-p-Benzoylphenylalanine
Packaging: 250mg
Price: $92
Updated: 2021/12/16

Activate Scientific

Product number: AS43582
Product name: (S)-2-Amino-3-(4-benzoylphenyl)propanoic acid
Purity: 95% ee
Packaging: 1g
Price: $98
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48340
Product name: 4-Benzoyl-L-phenylalanine
Packaging: 2g
Price: $120
Updated: 2021/12/16

AK Scientific

Product number: O027
Product name: L-p-Benzoylphenylalanine
Packaging: 1g
Price: $128
Updated: 2021/12/16

Apolloscientific

Product number: BIBA1027
Product name: H-p-Bz-Phe-OH
Packaging: 1g
Price: $129
Updated: 2021/12/16

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L-4-BENZOYLPHENYLALANINE Chemical Properties,Usage,Production

Chemical Properties

Off-white solid

Uses

4-Benzoyl-L-phenylalanine is a photoreactive amino acid which can easily be incorporated into a peptide by solid-phase synthesis and finds application as phtolabel. It is an important raw material as well as an intermediate in organic synthesis.

Synthesis

63-91-2

98-88-4

104504-45-2

The general procedure for the synthesis of (S)-2-amino-3-(4-benzoylphenyl)propionic acid from L-phenylalanine and benzoyl chloride was as follows: in a reaction tube fitted with a screw cap and polytetrafluoroethylene (PTFE)-faced rubber lining, L-phenylalanine (16.5 mg, 0.1 mmol) was added followed by trifluoromethanesulfonic acid (0.5 mL). After the solution was homogenized, benzoyl chloride (8 eq.) was added slowly at 0 °C. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the mixture was poured into a mixture of cold water and ethyl acetate. The organic layer was separated, washed with saturated sodium chloride solution, dried over anhydrous magnesium sulfate and filtered. The filtrate was concentrated and the residue was purified by silica gel column chromatography (eluent ratio ethyl acetate:methanol:water=8:1:0.5) to give a colorless amorphous product (7.5 mg, 28% yield, 98% enantiomeric excess value). The structure of the product was confirmed by 1H-NMR (CD3OD): δ 7.76 (d, 2H, J=8.6 Hz, Ar), 7.75 (d, 2H, J=8.6 Hz, Ar), 7.64 (t, 1H, J=7.4 Hz, Ar), 7.52 (t, 2H, J=7.4 Hz, Ar), 7.47 (d, 2H, J=8.0 Hz, Ar ), 3.83(m, 1H, Hα), 3.35(m, 1H, Hβ), 3.09(m, 1H, Hβ).

storage

Store at +4°C

References

[1] Molecules, 2013, vol. 18, # 7, p. 8393 - 8401
[2] Heterocycles, 2013, vol. 87, # 10, p. 2119 - 2126

L-4-BENZOYLPHENYLALANINE Preparation Products And Raw materials

Raw materials

Preparation Products

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L-4-BENZOYLPHENYLALANINE Suppliers

China 113 Germany 1 India 1 Japan 1 United Kingdom 3 United States 19 Global 138

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
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Alfa Aesar

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Shanghai Hanhong Scientific Co.,Ltd.

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Chemsky (shanghai) International Co.,Ltd

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ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
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View Lastest Price from L-4-BENZOYLPHENYLALANINE manufacturers

Career Henan Chemical Co

Product: L-4-BENZOYLPHENYLALANINE 104504-45-2
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-22

104504-45-2, L-4-BENZOYLPHENYLALANINERelated Search:

4-Methylphenyl-L-alanine L-PHE(4-COCH3) H-PHE-ALA-OH PHE-GLY-GLY H-4-NITRO-PHE-OET HCL L-4-Iodophenylalanine 4-Methoxy-L-phenylalanine L-4-Chlorophenylalanine L-4-Fluorophenylalanine L-4-TERT-BUTYL-PHE H-Phe-D-Phe-OMe.HCl L-4-Nitrophenylalanine methyl ester hydrochloride 4-AMINOTETRAHYDROPYRAN-4-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE L-4-Cyanophenylalanine 4-Amino-L-phenylalanine hydrochloride METHYL 4-BROMO-L-PHENYLALANINATE HYDROCHLORIDE H-Phe(4-Cl)-OMe.HCl 4-Amino-L-phenylalanine

(S)-2-aMino-3-(4-benzoylphenyl)propanoic acid

p-benzoyl-L-phenylanaline

(2S)-2-aMino-3-(4-benzoylphenyl)propanoic acid

H-4-Bz-Phe-Oh

H-Bpa-OH H-Phe(4-Bz)-OH

L-4-BENZOYLPHENYLALANINE 1G

H-Bpa-OH H-Phe(4-Bz)

4-Benzoyl-L-phenylalanine≥ 99% (HPLC, Chiral purity)

H-L-Phe(4-Bz)-OH

L-Bpa-OH

4-BENZOYL-L-PHENYLALANINE

P-BENZOYL-L-PHENYLALANINE

P-BZ-PHENYLALANINE

L-P-BENZOYLPHENYLALANINE

H-PHE(P-BZ)-OH

H-PHE(4-BZ)-OH

H-PHE(4-BZO)-OH

H-P-BZ-PHE-OH

L-4-BENZOYLPHENYLALANINE

H-BPA-OH

4-Benzoylphenylalanine

Al660-1

4-Benzoyl-L-phenylalanine，98%

L-Phenylalanine, 4-benzoyl-

(S)-2-Amino-3-(4-benzoylphenyl)propanoicaci

(S) 2-Amino-3- (4-benzoylphenyl) propionic acid

(R)-3-amino-3-(3-(p-tolyloxy)phenyl)propanoic acid

104504-45-2

Phenylalanine analogs and other aromatic alpha amino acids

Amino Acid Derivatives

Amino Acids

proteins

Chiral Compound

a-amino