Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

Product Name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
CAS No.: 887267-53-0
Chemical Name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Synonyms: Ethyl 3-(2,5-difluorophenyl);ETHYL 2,5-DIFLUOROBENZOYLACETATE;Ethyl 2,5-difluoro-β-oxobenzenepropanoate;ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%;Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester;3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester;2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester
CBNumber: CB3689431
Molecular Formula: C11H10F2O3
Formula Weight: 228.19
MOL File: 887267-53-0.mol

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Property

Boiling point:: 275.7±25.0 °C(Predicted)
Density: 1.251±0.06 g/cm3(Predicted)
pka: 10.28±0.50(Predicted)

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Safety

HS Code: 2916399090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC

Product number: E916705
Product name: Ethyl3-(2,5-Difluorophenyl)-3-oxopropanoate
Packaging: 500mg
Price: $285
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2629-3-30
Product name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Purity: 97%
Packaging: 250mg
Price: $291
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2629-3-30
Product name: Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Purity: 97%
Packaging: 1g
Price: $795
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0007231
Product name: ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE
Purity: 95.00%
Packaging: 5G
Price: $909.56
Updated: 2021/12/16

AK Scientific

Product number: 4567AC
Product name: Ethyl3-(2,5-difluorophenyl)-3-oxopropanoate
Packaging: 5g
Price: $1063
Updated: 2021/12/16

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Chemical Properties,Usage,Production

Uses

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate is commonly utilized in organic synthesis as C-nucleophiles. One specific example is its reaction with the N-terminal electrophile CF3CHN2, resulting in the formation of CF3-heterocycles, namely ethyl 6-fluoro-4-oxo-1-(2,2,2-trifluoroethyl)-1,4-dihydrocinnoline-3-carboxylate[1].

References

[1] Arkhipov A, et al. Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal N?Atom. Organic Letters, 2016; 18: 3406–3409.

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Suppliers

China 43 India 1 Ukraine 1 United Kingdom 2 United States 9 Global 56

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887267-53-0, Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoateRelated Search:

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ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE

ETHYL 2,5-DIFLUOROBENZOYLACETATE

3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester

Ethyl 3-(2,5-difluorophenyl)

2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%

Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester

Ethyl 2,5-difluoro-β-oxobenzenepropanoate

887267-53-0