ChemicalBook > CAS DataBase List > Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate

Product Name
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
CAS No.
887267-53-0
Chemical Name
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Synonyms
Ethyl 3-(2,5-difluorophenyl);ETHYL 2,5-DIFLUOROBENZOYLACETATE;Ethyl 2,5-difluoro-β-oxobenzenepropanoate;ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE;Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate 95+%;Benzenepropanoic acid, 2,5-difluoro-β-oxo-, ethyl ester;3-(2,5-Difluoro-phenyl)-3-oxo-propionic acid ethyl ester;2-fluoro-3-(3-fluorophenyl)-3-oxopropanoic acid ethyl ester
CBNumber
CB3689431
Molecular Formula
C11H10F2O3
Formula Weight
228.19
MOL File
887267-53-0.mol
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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Property

Boiling point:
275.7±25.0 °C(Predicted)
Density 
1.251±0.06 g/cm3(Predicted)
pka
10.28±0.50(Predicted)
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Safety

HS Code 
2916399090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TRC
Product number
E916705
Product name
Ethyl3-(2,5-Difluorophenyl)-3-oxopropanoate
Packaging
500mg
Price
$285
Updated
2021/12/16
SynQuest Laboratories
Product number
2629-3-30
Product name
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Purity
97%
Packaging
250mg
Price
$291
Updated
2021/12/16
SynQuest Laboratories
Product number
2629-3-30
Product name
Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate
Purity
97%
Packaging
1g
Price
$795
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0007231
Product name
ETHYL 3-(2,5-DIFLUOROPHENYL)-3-OXOPROPANOATE
Purity
95.00%
Packaging
5G
Price
$909.56
Updated
2021/12/16
AK Scientific
Product number
4567AC
Product name
Ethyl3-(2,5-difluorophenyl)-3-oxopropanoate
Packaging
5g
Price
$1063
Updated
2021/12/16
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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Chemical Properties,Usage,Production

Uses

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate is commonly utilized in organic synthesis as C-nucleophiles. One specific example is its reaction with the N-terminal electrophile CF3CHN2, resulting in the formation of CF3-heterocycles, namely ethyl 6-fluoro-4-oxo-1-(2,2,2-trifluoroethyl)-1,4-dihydrocinnoline-3-carboxylate[1].

References

[1] Arkhipov A, et al. Unexpected Reactivity of Trifluoromethyl Diazomethane (CF3CHN2): Electrophilicity of the Terminal N?Atom. Organic Letters, 2016; 18: 3406–3409.

Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoate Suppliers

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887267-53-0, Ethyl 3-(2,5-difluorophenyl)-3-oxopropanoateRelated Search:

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