Glycylglycine
- Product Name
- Glycylglycine
- CAS No.
- 556-50-3
- Chemical Name
- Glycylglycine
- Synonyms
- GLY-GLY;H-GLY-GLY-OH;DIGLYCINE;GLY-GLY-OH;N-GLYCYLGLYCINE;2-(2-aMinoacetaMido)acetic acid;2-[(2-Aminoacetyl)amino]acetic acid;Gly2;y-GL;Gly-Gl
- CBNumber
- CB3704259
- Molecular Formula
- C4H8N2O3
- Formula Weight
- 132.12
- MOL File
- 556-50-3.mol
Glycylglycine Property
- Melting point:
- 220-240 °C (dec.)
- Boiling point:
- 267.18°C (rough estimate)
- Density
- 1.5851 (rough estimate)
- vapor pressure
- 0.058Pa at 20-50℃
- refractive index
- 1.4880 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- H2O: 1 M at 20 °C, clear, colorless
- pka
- 3.139(at 25℃)
- form
- Solid
- color
- White
- PH
- 4.5-6.0 (20℃, 1M in H2O)
- PH Range
- 7.5 - 8.9
- Water Solubility
- SOLUBLE IN HOT WATER
- λmax
- λ: 260 nm Amax: 0.075
λ: 280 nm Amax: 0.072 - Merck
- 14,4503
- BRN
- 1765223
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChIKey
- YMAWOPBAYDPSLA-UHFFFAOYSA-N
- LogP
- -0.92 at 25℃ and pH6
- CAS DataBase Reference
- 556-50-3(CAS DataBase Reference)
- NIST Chemistry Reference
- N-Glycylglycine(556-50-3)
- EPA Substance Registry System
- Glycylglycine (556-50-3)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 50199
- Product name
- Gly-Gly
- Purity
- BioUltra, ≥99.5% (NT)
- Packaging
- 10g
- Price
- $80.1
- Updated
- 2024/03/01
- Product number
- 50199
- Product name
- Gly-Gly
- Purity
- BioUltra, ≥99.5% (NT)
- Packaging
- 50g
- Price
- $303
- Updated
- 2024/03/01
- Product number
- G0124
- Product name
- Glycylglycine
- Purity
- >99.0%(T)
- Packaging
- 25g
- Price
- $41
- Updated
- 2024/03/01
- Product number
- G0124
- Product name
- Glycylglycine
- Purity
- >99.0%(T)
- Packaging
- 100g
- Price
- $124
- Updated
- 2024/03/01
- Product number
- A10523
- Product name
- Glycylglycine, 99%
- Packaging
- 25g
- Price
- $53.1
- Updated
- 2024/03/01
Glycylglycine Chemical Properties,Usage,Production
Chemical Properties
White crystals
Uses
Glycylglycine is as a buffering reagent and also used in biochemical research. It is the simplest of all dipeptides and is used as a starting template for preparation of more complex peptides. It is also employed as a practical buffer with a buffering range of 7.5 - 8.9 (at 25°C). Valuable agent for experiments investigating peptide transport and absorption.
Definition
ChEBI: A dipeptide formed from glycine residues.
Synthesis Reference(s)
Journal of the American Chemical Society, 75, p. 5323, 1953 DOI: 10.1021/ja01117a053
Biochem/physiol Actions
Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid. Diglycine is known to catalyze the formation of homo- and hetero dipeptides more efficiently than glycine.
Purification Methods
Crystallise glycylglycine from aqueous 50% EtOH or water at 50-60o by addition of EtOH. Dry it at 110o. It sublimes at 190-200o/0.3mm with 30% recovery [Gross & Gradsky J Am Chem Soc 77 1678 1955, King J Am Chem Soc 79 6153 1957]. [Beilstein 4 IV 2459.]
Glycylglycine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Glycylglycine manufacturers
- Product
- Glycylglycine 556-50-3
- Price
- US $999.00-800.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-22
- Product
- Gly-Gly-OH 556-50-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-01-17
- Product
- Glycylglycine 556-50-3
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 99%min
- Supply Ability
- 1000kg/month
- Release date
- 2021-07-06