2,2,6,6-Tetramethyl-4-piperidone hydrochloride

Product Name: 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
CAS No.: 33973-59-0
Chemical Name: 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
Synonyms: TMP=O;TEMPIDONE;TIMTEC-BB SBB003626;TRIACETONAMINE HYDROCHLORIDE;TRIACETONEAMINE HYDROCHLORIDE;2,2,6,6-Tetramethyl-4-piperidoneHCl;2,2,6,6-tetramethyl-4-piperidin-1-iumone;2,2,6,6-TETRAMETHYLPIPERIDONE-4 HYDROCHLORIDE;2,2,6,6-TETRAMETHYL-4-PIPERIDONE HYDROCHLORIDE;2,2,6,6-tetramethyl-4-piperidinonhydrochloride
CBNumber: CB3718942
Molecular Formula: C9H18ClNO
Formula Weight: 191.7
MOL File: 33973-59-0.mol

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2,2,6,6-Tetramethyl-4-piperidone hydrochloride Property

Melting point:: 198 °C (dec.)(lit.)
storage temp.: Sealed in dry,Room Temperature
form: powder
color: White to off-white
BRN: 4154554
InChI: 1S/C9H17NO.ClH/c1-8(2)5-7(11)6-9(3,4)10-8;/h10H,5-6H2,1-4H3;1H
InChIKey: ZXNWYMNKYXUZGM-UHFFFAOYSA-N
SMILES: Cl[H].CC1(C)CC(=O)CC(C)(C)N1
LogP: 1.323 (est)
CAS DataBase Reference: 33973-59-0(CAS DataBase Reference)
EPA Substance Registry System: 4-Piperidinone, 2,2,6,6-tetramethyl-, hydrochloride (33973-59-0)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-24/25
WGK Germany: 3
F: 8
Hazard Note: Irritant
TSCA: TSCA listed
HS Code: 2933399990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 115762
Product name: 2,2,6,6-Tetramethyl-4-piperidone hydrochloride
Purity: 98%
Packaging: 25g
Price: $64.5
Updated: 2023/06/20

AK Scientific

Product number: P293
Product name: 2,2,6,6-Tetramethyl-4-piperidoneHCl
Packaging: 25g
Price: $140
Updated: 2021/12/16

Chem-Impex

Product number: 43524
Product name: 2,2,6,6-Tetramethyl-4-piperidonehydrochloride,≥95%(Assaybytitration)
Purity: ≥95%(Assaybytitration)
Packaging: 25G
Price: $75.11
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H17-5-11
Product name: 2,2,6,6-Tetramethylpiperidin-4-one hydrochloride
Purity: 97%
Packaging: 25g
Price: $112
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H17-5-11
Product name: 2,2,6,6-Tetramethylpiperidin-4-one hydrochloride
Purity: 97%
Packaging: 100g
Price: $224
Updated: 2021/12/16

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2,2,6,6-Tetramethyl-4-piperidone hydrochloride Chemical Properties,Usage,Production

Chemical Properties

white to slightly beige crystalline powder

Uses

2,2,6,6-Tetramethyl-4-piperidone hydrochloride has been used as a reagent injected in the micromixer using a Rheodyne injection valve for introducing discrete sample pulses into the miniaturised-SYNthesis and Total Analysis System (πSYNTAS).

in vivo

Triacetonamine (Purchased from MCE; 200 mg, 300 mg, 400 mg/Kg/day; gavage; 2 days) hydrochloride shows typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality^[2].

Animal Model:	Rats (half male and female, 6-8 weeks old, 200±10 g)^[2]
Dosage:	200 mg, 300 mg, 400 mg/Kg
Administration:	Gavage; daily; 2 days
Result:	Showed typical hepatoenteropathology of ALF with 300 mg/Kg/day and 400 mg/Kg/day, while the group of 400 mg/Kg/day had higher mortality.

Purification Methods

Purify the salt by recrystallisation from EtOH/Et2O, MeCN or Me2CO/MeOH. The free base has m 37-39o (after sublimation), b 102-105o/18mm, and the hydrate has m 56-58o (wet Et2O); the hydrobromide has m 203o (from EtOH/Et2O), and the picrate has m 196o (from aqueous EtOH). [Sandris & Ourisson Bull Soc Chim Fr 345 1958, Beilstein 21 H 246, 21 I 273, 21 II 222, 21 III/IV 3278, 21/6 V 538.]

2,2,6,6-Tetramethyl-4-piperidone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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2,2,6,6-Tetramethyl-4-piperidone hydrochloride Suppliers

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33973-59-0, 2,2,6,6-Tetramethyl-4-piperidone hydrochlorideRelated Search:

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2,2,6,6-Tetramethyl-4-piperidinone·hydrochloride

2,2,6,6-Tetramethyl-4-piperidone hydrochloride,97%

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2,2,6,6-TETRAMETHYLPIPERIDONE-4 HYDROCHLORIDE

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TIMTEC-BB SBB003626

TMP=O

TEMPIDONE

2,2,6,6-tetramethyl-4-piperidinonhydrochloride

2,2,6,6-tetramethylpiperidin-4-one hydrochloride

TRIACETONEAMINE HYDROCHLORIDE

TRIACETONAMINE HYDROCHLORIDE

2,2,6,6-tetramethyl-4-piperidin-1-iumone

2,2,6,6-Tetramethyl-4-piperidoneHCl

2,2,6,6-Tetramethylpiperidin-4-one hydrochloride 97%

2,2,6,6-TETRAMETHYL-4-PIPERIDONE HYDROCHLORIDE 97%

Recombinant Human Thymopoietin/TMPO Protein, His Tag

33973-59-0

928-42-4

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