ChemicalBook > CAS DataBase List > MS1943

MS1943

Product Name
MS1943
CAS No.
2225938-17-8
Chemical Name
MS1943
Synonyms
MS1943;MS1943, 10 mM in DMSO;1,6-Dimethyl-2-aminomethyl-3-benzyloxypyridin-4(1H)-one;MS 1943,degrader,Histone Methyltransferase,breast,Apoptosis,inhibit,triple-negative,proliferation,methyltransferase,MS1943,cancer,Inhibitor,cytotoxic,MS-1943,TNBC;6-(6-(4-(2-(2-(Adamantan-1-yl)acetamido)ethyl)piperazin-1-yl)pyridin-3-yl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide;1H-Indazole-4-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-[2-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]ethyl]-1-piperazinyl]-3-pyridinyl]-
CBNumber
CB37243678
Molecular Formula
C42H54N8O3
Formula Weight
718.93
MOL File
2225938-17-8.mol
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MS1943 Property

Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in DMSO:100.0(Max Conc. mg/mL);139.1(Max Conc. mM)
form 
A solid
pka
12.56±0.46(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0112146
Product name
MS1943
Purity
98.18%
Packaging
5mg
Price
$770
Updated
2021/12/16
ChemScene
Product number
CS-0112146
Product name
MS1943
Purity
98.18%
Packaging
10mg
Price
$1300
Updated
2021/12/16
ChemScene
Product number
CS-0112146
Product name
MS1943
Purity
98.18%
Packaging
50mg
Price
$3900
Updated
2021/12/16
ChemScene
Product number
CS-0112146
Product name
MS1943
Purity
98.18%
Packaging
100mg
Price
$5300
Updated
2021/12/16
DC Chemicals
Product number
DC26169
Product name
MS1943
Packaging
250mg
Price
$1300
Updated
2021/12/16
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MS1943 Chemical Properties,Usage,Production

Uses

MS1943 is used in the preparation of heterocyclic compounds as EZH2 ligands and their compositions and methods for treating EZH2-mediated cancer. MS1943 itself significantly reduces EZH2 protein levels in numerous triple-negative breast cancer

MS1943 Preparation Products And Raw materials

Raw materials

Preparation Products

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MS1943 Suppliers

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2225938-17-8, MS1943Related Search:

1H-Isoindole-1,3(2H)-dione, 4-[[2-[4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]-2-oxoethyl]amino]-2-(2,6-dioxo-3-piperidinyl)- MS4078 MS4077

  • MS1943
  • 1,6-Dimethyl-2-aminomethyl-3-benzyloxypyridin-4(1H)-one
  • 1H-Indazole-4-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-[2-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]ethyl]-1-piperazinyl]-3-pyridinyl]-
  • 6-(6-(4-(2-(2-(Adamantan-1-yl)acetamido)ethyl)piperazin-1-yl)pyridin-3-yl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide
  • MS 1943,degrader,Histone Methyltransferase,breast,Apoptosis,inhibit,triple-negative,proliferation,methyltransferase,MS1943,cancer,Inhibitor,cytotoxic,MS-1943,TNBC
  • MS1943, 10 mM in DMSO
  • 2225938-17-8
  • C42H54N8O3