MS1943

Product Name: MS1943
CAS No.: 2225938-17-8
Chemical Name: MS1943
Synonyms: MS1943;MS1943, 10 mM in DMSO;1,6-Dimethyl-2-aminomethyl-3-benzyloxypyridin-4(1H)-one;MS 1943,degrader,Histone Methyltransferase,breast,Apoptosis,inhibit,triple-negative,proliferation,methyltransferase,MS1943,cancer,Inhibitor,cytotoxic,MS-1943,TNBC;6-(6-(4-(2-(2-(Adamantan-1-yl)acetamido)ethyl)piperazin-1-yl)pyridin-3-yl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide;1H-Indazole-4-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-[2-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]ethyl]-1-piperazinyl]-3-pyridinyl]-
CBNumber: CB37243678
Molecular Formula: C42H54N8O3
Formula Weight: 718.93
MOL File: 2225938-17-8.mol

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MS1943 Property

Density: 1.36±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in DMSO:100.0(Max Conc. mg/mL);139.1(Max Conc. mM)
form: A solid
pka: 12.56±0.46(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0112146
Product name: MS1943
Purity: 98.18%
Packaging: 5mg
Price: $770
Updated: 2021/12/16

ChemScene

Product number: CS-0112146
Product name: MS1943
Purity: 98.18%
Packaging: 10mg
Price: $1300
Updated: 2021/12/16

ChemScene

Product number: CS-0112146
Product name: MS1943
Purity: 98.18%
Packaging: 50mg
Price: $3900
Updated: 2021/12/16

ChemScene

Product number: CS-0112146
Product name: MS1943
Purity: 98.18%
Packaging: 100mg
Price: $5300
Updated: 2021/12/16

DC Chemicals

Product number: DC26169
Product name: MS1943
Packaging: 250mg
Price: $1300
Updated: 2021/12/16

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MS1943 Chemical Properties,Usage,Production

Uses

MS1943 is used in the preparation of heterocyclic compounds as EZH2 ligands and their compositions and methods for treating EZH2-mediated cancer. MS1943 itself significantly reduces EZH2 protein levels in numerous triple-negative breast cancer

Biological Activity

MS1943 is a potent and selective degrader of EZH2 (enhancer of zeste homolog 2) th at effectively reduces EZH2 levels in cells. MS1943 potently inhibits growth of multiple TNBC cells and in mice xenograft model.

MS1943 Preparation Products And Raw materials

Raw materials

Preparation Products

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MS1943 Suppliers

China 39 United States 3 Global 42

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7787
Advantage: 56

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Jilin Province Woda Biotechnology Co., Ltd.

Tel: 13504435624
Email: 1927928688@qq.com
Country: China
ProdList: 1466
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 4297
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Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd

Tel: 15317229551
Fax: QQ:3607245178
Email: 15151849396@163.com
Country: China
ProdList: 996
Advantage: 58

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
ProdList: 4331
Advantage: 58

2225938-17-8, MS1943Related Search:

1H-Isoindole-1,3(2H)-dione, 4-[[2-[4-[6-[(6-acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1-piperazinyl]-2-oxoethyl]amino]-2-(2,6-dioxo-3-piperidinyl)- MS4078 MS4077

MS1943

1,6-Dimethyl-2-aminomethyl-3-benzyloxypyridin-4(1H)-one

1H-Indazole-4-carboxamide, N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-[4-[2-[(2-tricyclo[3.3.1.13,7]dec-1-ylacetyl)amino]ethyl]-1-piperazinyl]-3-pyridinyl]-

6-(6-(4-(2-(2-(Adamantan-1-yl)acetamido)ethyl)piperazin-1-yl)pyridin-3-yl)-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-isopropyl-1H-indazole-4-carboxamide

MS 1943,degrader,Histone Methyltransferase,breast,Apoptosis,inhibit,triple-negative,proliferation,methyltransferase,MS1943,cancer,Inhibitor,cytotoxic,MS-1943,TNBC

MS1943, 10 mM in DMSO

2225938-17-8

C42H54N8O3