5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE
- Product Name
- 5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE
- CAS No.
- 7781-26-2
- Chemical Name
- 5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE
- Synonyms
- 5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE;2-Amino-5-bromo-4,6-dichloropyrimidine;2-Pyrimidinamine, 5-bromo-4,6-dichloro-;5-Bromo-4,6-dichloro-pyrimidin-2-ylamine;2-Amino-5-bromo-4,6-dichloropyrimidine97%;2-Amino-5-bromo-4,6-dichloropyrimidine 97%;5-Bromo-4,6-dichloropyrimidin-2-amine, 2-Amino-5-bromo-4,6-dichloro-1,3-diazine
- CBNumber
- CB3743294
- Molecular Formula
- C4H2BrCl2N3
- Formula Weight
- 242.89
- MOL File
- 7781-26-2.mol
5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE Property
- Boiling point:
- 419.4±55.0 °C(Predicted)
- Density
- 2.054±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- -1.47±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B700123
- Product name
- 5-Bromo-4,6-dichloropyrimidin-2-amine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3H30-D-X0
- Product name
- 2-Amino-5-bromo-4,6-dichloropyrimidine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $88
- Updated
- 2021/12/16
- Product number
- 3H30-D-X0
- Product name
- 2-Amino-5-bromo-4,6-dichloropyrimidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $168
- Updated
- 2021/12/16
- Product number
- 083950
- Product name
- 5-Bromo-4,6-dichloropyrimidin-2-amine
- Purity
- 97%
- Packaging
- 1g
- Price
- $341
- Updated
- 2021/12/16
- Product number
- HCH0030240
- Product name
- 2-AMINO-5-BROMO-4,6-DICHLOROPYRIMIDINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $1085.4
- Updated
- 2021/12/16
5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE Chemical Properties,Usage,Production
Synthesis
56-05-3
7781-26-2
The general procedure for the synthesis of 5-bromo-4,6-dichloropyrimidin-2-amine from 2-amino-4,6-dichloropyrimidine was as follows: over a period of 20 min, bromine (0.85 mL, 0.0166 mol) was slowly added dropwise to a stirring 1:1 mixture of 2-amino-4,6-dichloropyrimidine (CAS # 56-05-3, 1.70 g, 0.01037 mol) and sodium carbonate ( 1.00 g, 0.01244 mol) in a 1:1 methanol/water (30 mL) mixture and the reaction was carried out at room temperature. Ten minutes after completion of the dropwise addition, additional sodium carbonate (0.78 g, 0.0093 mol) was added to the reaction mixture. The reaction mixture was continued to be stirred at room temperature for 42 hours. Upon completion of the reaction, the reaction mixture was diluted with aqueous sodium bicarbonate to precipitate 5-bromo-4,6-dichloropyrimidin-2-amine precipitate which was collected by filtration and washed with distilled water. Vacuum drying gave 2.11 g of white solid in 83.7% yield. The product was characterized by 1H NMR (300 MHz, d6-DMSO): δ 7.67 (s, 1H), 7.70 (s, 1H). Mass spectrum (DC1-NH3) showed: m/z = 241 (M + H)+, m/z = 258 (M + NH4)+.
References
[1] Patent: US2004/204386, 2004, A1
[2] Patent: US2010/331294, 2010, A1. Location in patent: Page/Page column 18
[3] Yakugaku Zasshi, 1942, vol. 62, p. 315,333; dtsch. Ref. S. 95, 106
[4] Chem.Abstr., 1951, p. 5150
5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE manufacturers
- Product
- 5-BROMO-4,6-DICHLOROPYRIMIDIN-2-AMINE 7781-26-2
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2024-08-05