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2-Cyclopenten-1-one

Product Name
2-Cyclopenten-1-one
CAS No.
930-30-3
Chemical Name
2-Cyclopenten-1-one
Synonyms
2-CYCLOPENTEN-1-ONE;Cyclopentenone;CYCLOPENT-2-ENONE;2-CYCLOPENTENE-1-ONE;CPEO;2-CycL;NSC 73117;openten-1-one;2-CYCLOPENTENONE;Cyclopenten-3-one
CBNumber
CB3744099
Molecular Formula
C5H6O
Formula Weight
82.1
MOL File
930-30-3.mol
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2-Cyclopenten-1-one Property

Boiling point:
64-65 °C19 mm Hg(lit.)
Density 
0.98 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.481(lit.)
Flash point:
108 °F
storage temp. 
2-8°C
solubility 
soluble in Chloroform, Methanol
form 
Liquid
color 
Clear yellow
Specific Gravity
0.980
Water Solubility 
almost insoluble
BRN 
1446054
InChI
InChI=1S/C5H6O/c6-5-3-1-2-4-5/h1,3H,2,4H2
InChIKey
BZKFMUIJRXWWQK-UHFFFAOYSA-N
SMILES
C1(=O)CCC=C1
LogP
-0.114 (est)
CAS DataBase Reference
930-30-3(CAS DataBase Reference)
NIST Chemistry Reference
2-Cyclopenten-1-one(930-30-3)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
10-37-36/37/38-22
Safety Statements 
16-36-36/37/39
RIDADR 
UN 1224 3/PG 3
WGK Germany 
3
8
Hazard Note 
Irritant
HazardClass 
3
PackingGroup 
III
HS Code 
29142990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C112909
Product name
2-Cyclopenten-1-one
Purity
98%
Packaging
5g
Price
$82.1
Updated
2024/03/01
Sigma-Aldrich
Product number
C112909
Product name
2-Cyclopenten-1-one
Purity
98%
Packaging
25g
Price
$195
Updated
2024/03/01
TCI Chemical
Product number
C0794
Product name
2-Cyclopenten-1-one
Purity
>96.0%(GC)
Packaging
5mL
Price
$57
Updated
2024/03/01
TCI Chemical
Product number
C0794
Product name
2-Cyclopenten-1-one
Purity
>96.0%(GC)
Packaging
25mL
Price
$198
Updated
2024/03/01
Alfa Aesar
Product number
B23408
Product name
2-Cyclopenten-1-one, 98%
Packaging
5g
Price
$74.5
Updated
2024/03/01
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2-Cyclopenten-1-one Chemical Properties,Usage,Production

Description

2-Cyclopentenone contains two functional groups, a ketone and an alkene. It is a colourless liquid. 2-cyclopenten-1-one selectively induces the expression of the 70-kDa HSP (HSP70) in human cells through cycloheximide-sensitive activation of heat shock transcription factor 1 (HSF1). It is a natural product found in Perilla frutescens[1].

Chemical Properties

clear yellow liquid

Uses

2-Cyclopenten-1-one is a versatile electrophile employed in various addition reactions including conjugate addition of organocopper nucleophiles, Michael reaction with silyl enol ethers and siloxanes. It is also used in Diels-Alder cycloadditions and phosphoniosilylations.

Definition

ChEBI: 2-cyclopenten-1-one is an enone that is cyclopentanone having a C=C double bond at position 2. It has a role as a Hsp70 inducer. It is an enone and an alicyclic ketone.

Preparation

2-Cyclopentenones can be synthesized in a number of ways. One of the routes involves elimination of α-bromo-cyclopentanone using lithium carbonate and Claisen condensation-decarboxylation-isomerization cascades of unsaturated diesters as shown below.

The acid-catalyzed dehydration of cyclopentanediols affords cyclopentenone.
As a functional group, the synthesis of 2-cyclopentenones is accomplished in a variety of other ways, including the Nazarov cyclization reaction from divinyl ketones, Saegusa–Ito oxidation from cyclopentanones, ring-closing metathesis from the corresponding dienes, oxidation of the corresponding cyclic allylic alcohols, and the Pauson–Khand reaction from alkenes, alkynes, and carbon monoxide.
en.wikipedia.org

References

[1] A Rossi, M G Santoro, G Elia. “2-Cyclopenten-1-one, a new inducer of heat shock protein 70 with antiviral activity.” The Journal of Biological Chemistry 271 50 (1996): 32192–6.

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2-Cyclopenten-1-one Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
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28387
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80
Chemicrea Co., Ltd.
Tel
--
Fax
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Country
Japan
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58
Melrob-Chemiplus Limited
Tel
--
Fax
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Email
info@melrob-chemiplus.com
Country
Japan
ProdList
208
Advantage
58
TCI Japan
Tel
--
Fax
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Email
@TCIchemicals.com
Country
Japan
ProdList
2741
Advantage
58
Nippon Zeon Co., Ltd
Tel
--
Fax
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Email
S.Jinji@zeon.co.jp
Country
Japan
ProdList
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75
Chemicrea Inc.
Tel
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Japan
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Wako Pure Chemical Industries, Ltd.
Tel
--
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Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
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80
Kanto Chemical Co., Inc.
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Email
reag-info@gms.kanto.co.jp
Country
Japan
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6756
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74
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View Lastest Price from 2-Cyclopenten-1-one manufacturers

Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
Product
2-Cyclopentenone 930-30-3
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
98%
Supply Ability
100kg
Release date
2023-03-08
Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
Product
2-Cyclopentenone 930-30-3
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
98%
Supply Ability
100kg
Release date
2023-03-08
Honest Joy Holdings Limited
Product
2-Cyclopentenone 930-30-3
Price
US $0.00/KG
Min. Order
1KG
Purity
97.9%
Supply Ability
100 tons
Release date
2022-02-21

930-30-3, 2-Cyclopenten-1-oneRelated Search:


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